Protein Alignment CG30491 and DHRS9

DIOPT Version :10

• Sequence 1: NP_610306.1
• Gene: CG30491 / 35704
• FlyBaseID: FBgn0050491
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_001276692.1
• Gene: DHRS9 / 10170
• HGNCID: 16888
• Length: 379
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 62/243 - (25%)
• Similarity: 102/243 - (41%)
• Gaps: 35/243 - (14%)

  Fly    14 WLSFTGTTTGLAFFVKDLM--------QGGQFTKETNETGKVFIVTGANTGIGKETVREIAKRGG 70
            :||.||..  :.|:|..|:        :.|:. |..:.|.|...:||.::|.|....|...|:|.
Human    53 YLSHTGGK--MLFWVLGLLILCGFLWTRKGKL-KIEDITDKYIFITGCDSGFGNLAARTFDKKGF 114

  Fly    71 TVYMACRNLKKCEEAREEIVLETKNKYVYCRQCDLASQESIRHFVAAFKRE--QEHLHVLINNAG 133
            .|..||..    |.....:..||..: :.....|:...|:::......|.:  ::.|..||||||
Human   115 HVIAACLT----ESGSTALKAETSER-LRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAG 174

  Fly   134 V--MRCPRS-LTSDGIELQLGVNHMGHFLLTNLLLDLLKKSSPSRIVNVSSLAHTRGEINTGDLN 195
            |  :..|.. ||.:.....:.||..|...:|..:|.|:||:. .|::||||:......:
Human   175 VPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQ-GRVINVSSVGGRLAIV------ 232

  Fly   196 SDKSYDEGKAYSQSKLANVLFTRELAKRLEGTNVTANALHPGVVDTEI 243
                   |..|:.||.|...|...|.:.::...|..:.:.||:..|.:
Human   233 -------GGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNL 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30491	NP_610306.1	Rossmann-fold NAD(P)(+)-binding proteins	45..319	CDD:473865	52/204 (25%)
DHRS9	NP_001276692.1	type2_17beta_HSD-like_SDR_c	90..366	CDD:187665	52/203 (26%)