Protein Alignment Rpt1 and AFG3

DIOPT Version :10

• Sequence 1: NP_477473.1
• Gene: Rpt1 / 35701
• FlyBaseID: FBgn0028687
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_010933.1
• Gene: AFG3 / 856737
• SGDID: S000000819
• Length: 761
• Species: Saccharomyces cerevisiae
• Alignment Length: 375
• Identity: 121/375 - (32%)
• Similarity: 181/375 - (48%)
• Gaps: 74/375 - (19%)

  Fly   112 IINVKQFAKFVVDLADSVAPTDIEEGMRVGVDRNKYQIHIPLPPKID-----------------P 159
            ::|.||...|.:...|.     .||.|    |:.:..::||...:|.                 |
Yeast   178 LVNTKQVVSFTIGSVDI-----FEEQM----DQIQDLLNIPPRDRIPIKYIERSSPFTFLFPFLP 233

  Fly   160 TVTMM--------QVEDKP-------------------------------DVTYSDVGGCKEQIE 185
            |:.::        ::...|                               .:::.:|.||.|..:
Yeast   234 TIILLGGLYFITRKINSSPPNANGGGGGGLGGMFNVGKSRAKLFNKETDIKISFKNVAGCDEAKQ 298

  Fly   186 KLREVVETPLLHPEKFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYV 250
            ::.|.|.. |.:|.|:..||.:.|:|.:|.|||||||||.|:|.|...:..|:.|.|||.|:.:|
Yeast   299 EIMEFVHF-LKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSGSEFVEMFV 362

  Fly   251 GEGARMVRELFEMARSKKACLIFFDEIDAIGGARFDDGA--GGDNEVQRTMLELINQLDGFDPRG 313
            |.||..||:||..|||....:||.|||||||..|...||  |.::|.:.|:.:|:.::|||....
Yeast   363 GVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALGGANDEREATLNQLLVEMDGFTTSD 427

  Fly   314 NIKVLMATNRPDTLDPALMRPGRLDRKVEFGLPDQDGRSHIFKIHARSMSVERDIRFDL------ 372
            .:.||..|||||.||.|||||||.||.::...||.:||..|:.:|.:.::::..:..|:
Yeast   428 QVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRLNLDPLLTDDMNNLSGK 492

  Fly   373 LARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVKKVIKSYAK 422
            ||.|.|..|||:|.:.|.||.:.|.|......|...|.:|:::||....|
Yeast   493 LATLTPGFTGADIANACNEAALIAARHNDPYITIHHFEQAIERVIAGLEK 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt1	NP_477473.1	PRK03992	88..430	CDD:179699	121/375 (32%)
AFG3	NP_010933.1	FtsH_ext	124..215	CDD:377663	11/45 (24%)
		FtsH_fam	223..730	CDD:273520	109/321 (34%)