Protein Alignment Rpt1 and GK2

DIOPT Version :9

• Sequence 1: NP_477473.1
• Gene: Rpt1 / 35701
• FlyBaseID: FBgn0028687
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_149991.2
• Gene: GK2 / 2712
• HGNCID: 4291
• Length: 553
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 97/490 - (19%)
• Similarity: 155/490 - (31%)
• Gaps: 163/490 - (33%)

  Fly    16 EKEDKEI------------KSLDEGDIEL--LKTYGQSQYHKSI----KSIEEDIQKAV------ 56
            |::.|||            :.|||.:|::  :|..|.|...::.    |...|.:..||
Human    54 EQDPKEILQSVYECIARTCEKLDELNIDISNIKAVGVSNQRETTVIWDKLTGEPLYNAVVWLDLR 118

  Fly    57 ---------KQVNELTGIKESDTGLAPPALWDLAADKQILQNEQPLQVA---------------- 96
                     |::...:...:|.|||.....:.....:.:|.|.:.:|.|
Human   119 TQTTVEDLSKKIPGNSNFVKSKTGLPLSTYFSAVKLRWMLDNVRNVQKAVEEGRALFGTIDSWLI 183

  Fly    97 -----------RCTKIINADSDDPKYIINVK---------QFAKFVVDLADSVAPTD-----IEE 136
                       .||.:.||..   ..:.|:.         .|.:..:||..:|..:.     |:.
Human   184 WSLTGGVNGGVHCTDVTNASR---TMLFNIHSLEWDKELCDFFEIPMDLLPNVFSSSEIYGLIKT 245

  Fly   137 GMRVGVDRNKYQIHIPLPPKIDPTVT-----MMQVEDKPDVTYSDVGGCKEQIEKLREVV--ETP 194
            |...||         |:...:.....     |...|.:...||..  ||.......|:.|  |..
Human   246 GALEGV---------PISGCLGDQCAALVGQMCFQEGQAKNTYGT--GCFLLCNTGRKCVFSEHG 299

  Fly   195 LLHPEKFVNLGIEPPKGVLLFGPPGTGKTLCARAV-----------------------ANRTDAC 236
            ||....: .||.|.|....|     .|....|.||                       ...:..|
Human   300 LLTTVAY-KLGREKPAYYAL-----EGSVAIAGAVIRWLRDNLGIIETSGDIERLAKEVGTSYGC 358

  Fly   237 FIRVIGSELVQKYVGEGARMVRELFEMARSKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLE 301
            :.....|.|...|....||.:  |..:.:....|.|.|..::|:   .|.         .|.:||
Human   359 YFVPAFSGLYAPYWEPSARGI--LCGLTQFTNKCHIAFAALEAV---CFQ---------TREILE 409

  Fly   302 LIN----------QLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKVEFGLPDQDGRSH--- 353
            .:|          |:||  ...|.||||.. :.|.|...:::| .:......|.....|.:.
Human   410 AMNRDCGIPLRHLQVDG--GMTNNKVLMQL-QADILHIPVIKP-FMPETTALGAAMAAGAAEGVS 470

  Fly   354 IFKIHARSMSVERDIRFDLLARLCP--NSTGAEIR 386
            ::.:..:::||.|..||:      |  .:|.:|||
Human   471 VWSLEPQALSVLRMERFE------PQIQATESEIR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt1	NP_477473.1	RPT1	27..430	CDD:224143	91/467 (19%)
GK2	NP_149991.2	FGGY_GK1-3_metazoa	11..513	CDD:212664	97/490 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900