DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43340 and IBSP

DIOPT Version :9

Sequence 1:	NP_001246184.1	Gene:	CG43340 / 35698	FlyBaseID:	FBgn0263077	Length:	3213	Species:	Drosophila melanogaster
Sequence 2:	NP_004958.2	Gene:	IBSP / 3381	HGNCID:	5341	Length:	317	Species:	Homo sapiens

Alignment Length:	188	Identity:	47/188 - (25%)
Similarity:	65/188 - (34%)	Gaps:	46/188 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1377 IEVVPLGSAELLSPSEPTEVVSPSAIALPEKPEPMENATEIEIEEMVSPTSVEIVPTTTEDLHQA 1441
            :....||..|..:|.  |.....:||.||:|...:.|....|.|               .|..:.
Human   107 LSATTLGYGEDATPG--TGYTGLAAIQLPKKAGDITNKATKEKE---------------SDEEEE 154

  Fly  1442 ESVVETARPVSAVEEVKPIEDSTAAIDKSPQISPIEGEHSQHSEKET----------PESVEVGL 1496
            |.           ||....|:|.|.:|::.|  .|.|..:..:|.|.          .|..|..:
Human   155 EE-----------EEGNENEESEAEVDENEQ--GINGTSTNSTEAENGNGSSGGDNGEEGEEESV 206

  Fly  1497 DSPNVADVITTSVEVIPTSTTAVTTSDGASTEMPEPPKIYCETAPPAAEEIEQNETVE 1554
            ...|..|...|..:...||.|  |||.....|...||::|..|:||    ..:..|||
Human   207 TGANAEDTTETGRQGKGTSKT--TTSPNGGFEPTTPPQVYRTTSPP----FGKTTTVE 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43340	NP_001246184.1	FYVE_BSN_PCLO	63..119	CDD:277290
IBSP	NP_004958.2	BSP_II	17..314	CDD:283165	47/188 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	58..254		44/182 (24%)
		cell-attachment tripeptide	286..288
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900