DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43340 and Muc18B

DIOPT Version :9

Sequence 1:	NP_001246184.1	Gene:	CG43340 / 35698	FlyBaseID:	FBgn0263077	Length:	3213	Species:	Drosophila melanogaster
Sequence 2:	NP_001285431.1	Gene:	Muc18B / 32913	FlyBaseID:	FBgn0031000	Length:	308	Species:	Drosophila melanogaster

Alignment Length:	310	Identity:	67/310 - (21%)
Similarity:	98/310 - (31%)	Gaps:	91/310 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1269 IDSLAAVESIDVKNQINSSNHMEQQNISIEPQPTVPMDTIQPIEIVQEVPCNTVDLIATTEAVNA 1333
            :.|:||.|:.|..|..|               ||:|...:.  |...|.|  ..:...|||.|..
  Fly    72 VQSIAAFEARDDSNIEN---------------PTIPPSNLD--ESTTEKP--ATEAPGTTEKVTT 117

  Fly  1334 DHSEPGEAGLISEVLQFHSSGGDLPETDSRAIEPLPLAPPAEVIEVVPLGSAELLSPSEP--TEV 1396
              :.||....::.         :.|.|..:.....|  ...|.|.....|:.|.::...|  ||.
  Fly   118 --AAPGTTEKVTT---------EAPGTTEKITTEAP--GTTEKITTEAPGTTEKITTEAPGTTEK 169

  Fly  1397 VSPSAIALPEKPEPMENATEIEIEEMVSPTSVEIVPTTTEDLHQAESVVETARPVSAVEEVKPIE 1461
            ::..|....|||     ||:              .|.|||         :.|.......|.....
  Fly   170 ITTEAPGTTEKP-----ATD--------------APGTTE---------KPATDAPGTTEKSETT 206

  Fly  1462 DSTAAIDKSPQISPIEGEHSQHSEKETPESVEVGLDSPN-----------VADVITTSVEVIPTS 1515
            |:....|||...:||..|         |.:.|...|.||           :.|.:..:..:.||.
  Fly   207 DAPGTTDKSDTDAPITDE---------PSTAETSTDEPNTETTESGEETTIEDNVCATTGLFPTG 262

  Fly  1516 --TTAVTTSDGASTEMPEPPKIYCETAPPAAEEIEQNETVETLSVSADTT 1563
              |..:..|.....|:    |.|.:..|   .|::.:......|.|.|.|
  Fly   263 SCTHFIVCSYAEGDEL----KAYTKKCP---GEMQFDPFNSVCSASYDCT 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43340	NP_001246184.1	FYVE_BSN_PCLO	63..119	CDD:277290
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884	67/310 (22%)
Muc18B	NP_001285431.1	MCLC	<77..177	CDD:283562	28/131 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900