Protein Alignment CG43340 and Leo1

DIOPT Version :9

• Sequence 1: NP_001246184.1
• Gene: CG43340 / 35698
• FlyBaseID: FBgn0263077
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: NP_001005548.1
• Gene: Leo1 / 300837
• RGDID: 1549772
• Length: 678
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 121/600 - (20%)
• Similarity: 197/600 - (32%)
• Gaps: 158/600 - (26%)

  Fly  1640 GVSEPEEATP----ATNNLTSGENPPEEVSELVDVEPRNPHE-------EIHTDSFEKDSQKSSD 1693
            |....||..|    :.|:....:|..|...|..|.|...|.:       |.|.|..:.|..:..|
  Rat    63 GDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDD 127

  Fly  1694 AVALHEDNTKSEEKVDPPQV--AEEVAPDIITLDPPSLVELSPDTQAMAIGNIAPFDIILEPESI 1756
                 ::..:|:|.....:.  :|:...|....|.....:.|.|.:.:...:
  Rat   128 -----DEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSD------------- 174

  Fly  1757 VIEQPVPVVKPETIVVESDPEAIDHTALLEPSVSAEVQDKVESAQQQVSENKS--VEEDSLKVSI 1819
                      .|.....||.|.:.::|           |:.|..|....|:::  .::|..::|.
  Rat   175 ----------DEEREQGSDDEKLQNSA-----------DEEEKMQNTDDEDRAQLSDDDRQQLSE 218

  Fly  1820 GERGEIISMDPITPADAVSEQNFRVED-PITSTESTAVEVIASESINTVVEPVSVAQSPTIEDST 1883
            .|:|......|....:...:||...|| |..|.|.                     :....:|..
  Rat   219 EEKGNSDDERPAASDNDEEKQNSDDEDRPQVSDEE---------------------KMQNSDDER 262

  Fly  1884 PEEVTQCSAVNSTDTEVASAAPIQVDQKIQPVHVELVSQIEASDLQES----------PKDTAQV 1938
            | :|:.....:|.|.|       :.|||.:        ....||.::.          |.| ::|
  Rat   263 P-QVSDEDRRHSDDEE-------EQDQKSE--------SARGSDSEDEVLRMKRKNAIPSD-SEV 310

  Fly  1939 ESDSVDQAILTQVSETDSIVVE---PSSPVKQSEDSQGEPPGSAQNVLDVGPVEMDQSAPEEVPE 2000
            :||       |:|.:.::..::   .:..:....|.:.:||...|.| |...:..||...|.:||
  Rat   311 DSD-------TEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPV-DENGLPQDQQEEEPIPE 367

  Fly  2001 TDPVAVEPSVP------------VEEEVIEVIQPAP-------KEISDSVERTLDSLGNTDLVAE 2046
            |   .:|..:|            |:......::|.|       .|..|  |..||..|.|.|..:
  Rat   368 T---RIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFED--EEMLDEEGRTRLKLK 427

  Fly  2047 AESV---DTPAENAGPEIGTSELEKELLVVSTTIDEQPSAVLEPLVLICQAESTNLDHE---LPE 2105
            .|:.   ....:..|.||    .|....:|..: |...|..|...|..........||.   :.:
  Rat   428 VENTIRWRMRRDEEGNEI----KESNARIVKWS-DGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQ 487

  Fly  2106 NLVPQGQSVPASLPTNLTIQTQPTDLETQPSMELILQTETVDAEMVKPVDMGDSTVDKSQETGEM 2170
            ....|||:|   ..|.||.:...||..|...|.|.|.......:.::.:.|...  |...:..||
  Rat   488 GTGLQGQAV---FKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGR--DPECQRTEM 547

  Fly  2171 VLKLESSKWEPLEAT 2185
            :.|.|    |.|.|:
  Rat   548 IKKEE----ERLRAS 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43340	NP_001246184.1	FYVE_BSN_PCLO	63..119	CDD:277290
Leo1	NP_001005548.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..373		75/397 (19%)
		PHA02664	<33..183	CDD:177447	24/147 (16%)
		PHA02664	<134..259	CDD:177447	27/179 (15%)
		Leo1	386..544	CDD:281933	38/169 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	559..596		121/599 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	613..678

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900