Protein Alignment CG43340 and Leo1

DIOPT Version :9

• Sequence 1: NP_001246184.1
• Gene: CG43340 / 35698
• FlyBaseID: FBgn0263077
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: NP_001034611.1
• Gene: Leo1 / 235497
• MGIID: 2685031
• Length: 667
• Species: Mus musculus
• Alignment Length: 603
• Identity: 119/603 - (19%)
• Similarity: 188/603 - (31%)
• Gaps: 180/603 - (29%)

  Fly  1642 SEPEEAT--PATNNLTSGENPPEEVSELVDVEPRNPHE-------EIHTDSFEKDSQKSSDAVAL 1697
            ||.|.|:  ..::|.:...:...|.||..|.|...|.:       |.|.|  :.|....||..:.
Mouse    66 SEEEGASHHSGSDNHSERSDNRSEASERSDHEDNEPSDEDQHSGSEAHND--DDDEGHRSDEGSR 128

  Fly  1698 HEDNTKSE------EKVDPPQVAEEVAPDIITLDPPSLVELSPDTQAMAIGNIAPFDIILEPESI 1756
            |.:...||      ||.|....::
Mouse   129 HSEAEGSEKAQSDDEKWDGEDKSD----------------------------------------- 152

  Fly  1757 VIEQPVPVVKPETIVVESDPEAIDHTALLEPSVSAEVQDKVESAQQQVSENKSVEEDSLKVSIGE 1821
                            :||.|.:.         :::.:|:.:.:.:...:|...:|:.::.:..|
Mouse   153 ----------------QSDDEKLQ---------NSDDEDREQGSDEDKLQNSDDDEEKMQNTDDE 192

  Fly  1822 RGEIISMDPITPADAVSEQNFRVEDPITSTESTAVEVIASESINTVVEPVSVAQSPTIEDSTPEE 1886
            ....||.|.........:.|...|.|:.|...       .|..|:..|     ..|.:.|   ||
Mouse   193 DRAQISDDDRQQLSEEEKGNSDDEHPVASDND-------EEKQNSDDE-----DQPQVSD---EE 242

  Fly  1887 VTQCSAVNSTDTEVASAAPIQVDQKIQPVHVELVSQIEASDLQESPKDTAQVESDSVDQAI---- 1947
            ..|.|                 |.:...|..|...:.:..:.|:...::|: .|||.|:.:
Mouse   243 KMQNS-----------------DDERPQVSDEDGRRSDGEEEQDQKSESAR-GSDSEDEVLRLKR 289

  Fly  1948 ---LTQVSETDSIVVEP------------SSPVKQSEDSQGEPPGSAQNVLDVGPVEMDQSAPEE 1997
               :...||.||....|            :..:....|.:.:||...|.| |...:..||...|.
Mouse   290 KNAIPSDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPV-DENGLPQDQQEEEP 353

  Fly  1998 VPETDPVAVEPSVP------------VEEEVIEVIQPAP-------KEISDSVERTLDSLGNTDL 2043
            :|||   .:|..:|            |:......::|.|       .|..|  |..||..|.|.|
Mouse   354 IPET---RIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFED--EEMLDEEGRTRL 413

  Fly  2044 VAEAESV---DTPAENAGPEIGTSELEKELLVVSTTIDEQPSAVLEPLVLICQAESTNLDHE--- 2102
            ..:.|:.   ....:..|.||    .|....:|..: |...|..|...|..........||.
Mouse   414 KLKVENTIRWRIRRDEEGNEI----KESNARIVKWS-DGSMSLHLGNEVFDVYKAPLQGDHNHLF 473

  Fly  2103 LPENLVPQGQSVPASLPTNLTIQTQPTDLETQPSMELILQTETVDAEMVKPVDMGDSTVDKSQET 2167
            :.:....|||:|   ..|.||.:...||..|...|.|.|.......:.::.:.|...  |...:.
Mouse   474 IRQGTGLQGQAV---FKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGR--DPECQR 533

  Fly  2168 GEMVLKLESSKWEPLEAT 2185
            .||:.|.|    |.|.|:
Mouse   534 TEMIKKEE----ERLRAS 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43340	NP_001246184.1	FYVE_BSN_PCLO	63..119	CDD:277290
Leo1	NP_001034611.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..362		73/400 (18%)
		PHA02664	<61..209	CDD:177447	33/210 (16%)
		Leo1	375..533	CDD:281933	38/169 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	548..585		119/603 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	602..667

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900