Protein Alignment CG43340 and DMP1

DIOPT Version :9

• Sequence 1: NP_001246184.1
• Gene: CG43340 / 35698
• FlyBaseID: FBgn0263077
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: XP_011530007.1
• Gene: DMP1 / 1758
• HGNCID: 2932
• Length: 542
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 120/586 - (20%)
• Similarity: 206/586 - (35%)
• Gaps: 164/586 - (27%)

  Fly  1283 QINSSNHMEQQNISIEPQPTVPMDTIQPIEIVQEVPCNTVDLIATTEAVNADHSE--PGEAGLIS 1345
            |.|.|...|:....:...||.|:::.:..|         ...:::.|..|.|.|:  ..|.||.|
Human    52 QNNESEDSEEWKGHLAQAPTPPLESSESSE---------GSKVSSEEQANEDPSDSTQSEEGLGS 107

  Fly  1346 EVLQF-----------HSSGGD-------------LPETDSRAIEPLPLAP-PAEVIEVVPLGSA 1385
            :..|:           ...|||             ..:.||        .| |.:..|.   |::
Human   108 DDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDS--------GPGPKDRQEG---GNS 161

  Fly  1386 ELLSPSEPTEVVSPSAIALPEKPEPMENATEIEIEEMVSPTSVEIVPTTTEDLHQAESVVETARP 1450
            .|.|..:..:.:..|..:.|:..:..::.|. |..|:.:...|:..|...:...::||
Human   162 RLGSDEDSDDTIQASEESAPQGQDSAQDTTS-ESRELDNEDRVDSKPEGGDSTQESES------- 218

  Fly  1451 VSAVEE--VKPIEDSTAAIDKSPQISPIEGEHSQHSE-------KETPESV--EVGLDSPNVADV 1504
                ||  |....|.             |..|...||       .:.|||:  |.|....|.|.:
Human   219 ----EEHWVGGGSDG-------------ESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGM 266

  Fly  1505 ITTSVEVIPTSTTAVTTSDGASTEMPEPP-KIYCETAPPAAE---EIEQNETVETLSVSADTTLP 1565
              .|.|....|..|.|...|.|..:..|. ||:.::.....:   |::.|.|:|  .|.:|:|
Human   267 --KSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTME--EVKSDST-- 325

  Fly  1566 EEIVSQDGNLEASEQTASIDVTFQANLNNMESKGCVEVAVDVRESKED--ETLMEPIAVDVAVPV 1628
            |...|:|..|....:               :|||         :|:||  |.|.:..:.:|..|.
Human   326 ENSNSRDTGLSQPRR---------------DSKG---------DSQEDSKENLSQEESQNVDGPS 366

  Fly  1629 EVVPQCAGVELGVSEPEEATPATNNLTS---GENPPEEVSELVDVEPRNPHEE--IHTDSFEKDS 1688
            ....|    |..:|..|.::.:...:.|   |:||....|.:.|.|..:..||  .||.|..|..
Human   367 SESSQ----EANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 427

  Fly  1689 QKSSDAVALHEDNTKSEEKVDPPQVAEEVAPDIITLDPPSLVELSPDTQAMAIGNIAPFDIILEP 1753
            .:...|      :::|.|.::..:.:.|...|..:.....|...|...::.:
Human   428 SREEQA------DSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQS------------- 473

  Fly  1754 ESIVIEQPVPVVKPETIVVESDPEAIDHTALLEPSVSAEVQDKVESAQQQVSENKSVEEDSLKVS 1818
                         .|:...|.|.::.|.:...|.|.|.|    .:|:.::..:.|::|.:|.|::
Human   474 -------------EESHSEEDDSDSQDSSRSKEDSNSTE----SKSSSEEDGQLKNIEIESRKLT 521

  Fly  1819 I 1819
            :
Human   522 V 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43340	NP_001246184.1	FYVE_BSN_PCLO	63..119	CDD:277290
DMP1	XP_011530007.1	DMP1	30..542	CDD:284637	120/586 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900