Protein Alignment CG43340 and LEO1

DIOPT Version :9

• Sequence 1: NP_001246184.1
• Gene: CG43340 / 35698
• FlyBaseID: FBgn0263077
• Length: 3213
• Species: Drosophila melanogaster
• Sequence 2: NP_001310832.1
• Gene: LEO1 / 123169
• HGNCID: 30401
• Length: 688
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 107/482 - (22%)
• Similarity: 169/482 - (35%)
• Gaps: 102/482 - (21%)

  Fly  1773 ESDPEAID-HTALLEPS---------------VSAEVQDKVESAQQQVS-ENKSVEEDSLKVSIG 1820
            ::||..:| |:....|:               ..||..:|..|..::.. |:||.:.|..|:...
Human    98 DNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNS 162

  Fly  1821 ---ERGEIISMDPITPADAVSE-QNFRVEDPITSTESTAVEVIASESINTVVE-PVSVAQSPTIE 1880
               ||.:....|.:..:|...: ||...|:....::....::...|..|:..| ||:.......:
Human   163 DDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQ 227

  Fly  1881 DSTPEEVTQCS---AVNSTDTEVASAAPIQVDQKIQPVHVELVSQIEASDLQESPKDTAQVESDS 1942
            :|..||..|.|   .:.::|.|...|:    |::    |.....:.|.....||.:.     |||
Human   228 NSDDEEQPQLSDEEKMQNSDDERPQAS----DEE----HRHSDDEEEQDHKSESARG-----SDS 279

  Fly  1943 VDQAI-------LTQVSETDSIVVEP------------SSPVKQSEDSQGEPPGSAQNVLDVGPV 1988
            .|:.:       :...||.||....|            :..:....|.:.:||...|.| |...:
Human   280 EDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPV-DENGL 343

  Fly  1989 EMDQSAPEEVPETDPVAVEPSVP------------VEEEVIEVIQPAP-------KEISDSVERT 2034
            ..||...|.:|||   .:|..:|            |:......::|.|       .|..|  |..
Human   344 PQDQQEEEPIPET---RIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFED--EEM 403

  Fly  2035 LDSLGNTDLVAEAESV---DTPAENAGPEIGTSELEKELLVVSTTIDEQPSAVLEPLVLICQAES 2096
            ||..|.|.|..:.|:.   ....:..|.||    .|....:|..: |...|..|...|.......
Human   404 LDEEGRTRLKLKVENTIRWRIRRDEEGNEI----KESNARIVKWS-DGSMSLHLGNEVFDVYKAP 463

  Fly  2097 TNLDHE---LPENLVPQGQSVPASLPTNLTIQTQPTDLETQPSMELILQTETVDAEMVKPVDMGD 2158
            ...||.   :.:....|||:|   ..|.||.:...||..|...|.|.|.......:.::.:.|..
Human   464 LQGDHNHLFIRQGTGLQGQAV---FKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAG 525

  Fly  2159 STVDKSQETGEMVLKLESSKWEPLEAT 2185
            .  |...:..||:.|.|    |.|.|:
Human   526 R--DPECQRTEMIKKEE----ERLRAS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43340	NP_001246184.1	FYVE_BSN_PCLO	63..119	CDD:277290
LEO1	NP_001310832.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..357		60/275 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..583		107/482 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900