Protein Alignment CG1358 and SLC49A3

DIOPT Version :9

• Sequence 1: NP_001188873.1
• Gene: CG1358 / 35697
• FlyBaseID: FBgn0033196
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: XP_024310012.1
• Gene: SLC49A3 / 84179
• HGNCID: 26177
• Length: 626
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 132/463 - (28%)
• Similarity: 214/463 - (46%)
• Gaps: 85/463 - (18%)

  Fly    66 YSSSN-----AMQ-WIQYTIINNIITRYYGISDKWVDWTSMIYMILYIPLIFPGSWFLDKVGLRI 124
            |||.:     .|| |:.:..:.::|.....:|.:.::|.|::|:::..|......|.||.||||
Human    99 YSSESRVLHCKMQLWLSFAPVADVIAEDLVLSMEQINWLSLVYLVVSTPFGVAAIWILDSVGLR- 162

  Fly   125 TALVGIVGTCVGAWIK-------------VFSVDPSLFYVSFIGQSIVALAQVCILSLPARLAAV 176
                  ..|.:|||:.             |.:.:|..|.:.  |||:.||||..::..||:|||:
Human   163 ------AATILGAWLNFAGSVLRMVPCMVVGTQNPFAFLMG--GQSLCALAQSLVIFSPAKLAAL 219

  Fly   177 WFGPDQVSSATSVGVFGNQLGVAVGFVLPPMLVPNSPDLETVGSDLQMM---FYLVAGLTSILLV 238
            ||...|.::|..:....|.|||.|..||.|:||..       |.|:.:|   :.:.||:  :.|:
Human   220 WFPEHQRATANMLATMSNPLGVLVANVLSPVLVKK-------GEDIPLMLGVYTIPAGV--VCLL 275

  Fly   239 LMVIFFQDKPPTPPSAAQEAAQLLESSEAEQVSFMQSLK-NLMTNRNFIFLLLSYGINVGVFYAI 302
            ..:..::..|||||||.  ||    ||.:|:  |:..|| .||.|:.::.|.:..|..:|:..:.
Human   276 STICLWESVPPTPPSAG--AA----SSTSEK--FLDGLKLQLMWNKAYVILAVCLGGMIGISASF 332

  Fly   303 STLLNPVVLKYYPGHEVD-AGRIGLSIVLAGMLGSVVSGIVLDKTHKFKETT---LAVYALSMVG 363
            |.||..::..  .||... :|..|...:..|:||::..|..:|:|..|.|.|   |.:::|:.|
Human   333 SALLEQILCA--SGHSSGFSGLCGALFITFGILGALALGPYVDRTKHFTEATKIGLCLFSLACV- 394

  Fly   364 MWIFTFTLDT---GHIAVVYLTASLLGFFMTGYLPVGFEFGAELTFPEPEGTSSGLLNASAQTFG 425
                .|.|.:   |....:..|.||||.|.....||..|...|.:||..||.::|::....|..|
Human   395 ----PFALVSQLQGQTLALAATCSLLGLFGFSVGPVAMELAVECSFPVGEGAATGMIFVLGQAEG 455

  Fly   426 ICFTLFYSEL--------FTTF--GDIAANITMAVMLIVG------TIITAITQSDLRRQNAQVP 474
            |...|..:.|        .:|.  |:...:.|::::|:.|      .|:.....:..||..|
Human   456 ILIMLAMTALTVRRSEPSLSTCQQGEDPLDWTVSLLLMAGLCTFFSCILAVFFHTPYRRLQA--- 517

  Fly   475 ASGQAGNP 482
               ::|.|
Human   518 ---ESGEP 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1358	NP_001188873.1	MFS_1	62..422	CDD:284993	116/385 (30%)
		MFS	63..461	CDD:119392	127/440 (29%)
SLC49A3	XP_024310012.1	MFS	113..508	CDD:119392	122/427 (29%)
		Herpes_UL49_2	<518..>623	CDD:331930	2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54923
OrthoDB	1	1.010	-	-		D425075at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100662
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.730