Protein Alignment HisT and FLVCR1

DIOPT Version :10

• Sequence 1: NP_610301.1
• Gene: HisT / 35697
• FlyBaseID: FBgn0033196
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_054772.1
• Gene: FLVCR1 / 28982
• HGNCID: 24682
• Length: 555
• Species: Homo sapiens
• Alignment Length: 470
• Identity: 231/470 - (49%)
• Similarity: 323/470 - (68%)
• Gaps: 8/470 - (1%)

  Fly     6 SAGGAGENSETFIATSKSTD-MITPKEKEGKGLKVAGGHNPPAEGYKVYARRWAVLILFVFYSSS 69
            :|.|.....:|.:|..:.|. .:.|   .|.|.:..|..:.|.....:..||:.||::|..||..
Human    59 AASGVLGGPQTPLAPEEETQARLLP---AGAGAETPGAESSPLPLTALSPRRFVVLLIFSLYSLV 120

  Fly    70 NAMQWIQYTIINNIITRYYGISDKWVDWTSMIYMILYIPLIFPGSWFLDKVGLRITALVGIVGTC 134
            ||.|||||:||:|:...:||::...:||.||:||:.|:|||||.:|.||..|||:|||:|....|
Human   121 NAFQWIQYSIISNVFEGFYGVTLLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLGSGLNC 185

  Fly   135 VGAWIKVFSVDPSLFYVSFIGQSIVALAQVCILSLPARLAAVWFGPDQVSSATSVGVFGNQLGVA 199
            :|||||..||...||:|:.:||.:.::|||.||.||:|:|:|||||.:||:|.:..|.|||||.|
Human   186 LGAWIKCGSVQQHLFWVTMLGQCLCSVAQVFILGLPSRIASVWFGPKEVSTACATAVLGNQLGTA 250

  Fly   200 VGFVLPPMLVPNSP-DLETVGSDLQMMFYLVAGLTSILLVLMVIFFQDKPPTPPSAAQEAAQLLE 263
            |||:|||:||||:. |...:..::..|||..:.:.::|.:|..|.|::||..|||.||.|   |:
Human   251 VGFLLPPVLVPNTQNDTNLLACNISTMFYGTSAVATLLFILTAIAFKEKPRYPPSQAQAA---LQ 312

  Fly   264 SSEAEQVSFMQSLKNLMTNRNFIFLLLSYGINVGVFYAISTLLNPVVLKYYPGHEVDAGRIGLSI 328
            .|..|:.|:.:|::||..|..|:.||::|||..|.||::|||||.::|.||.|.||:||||||::
Human   313 DSPPEEYSYKKSIRNLFKNIPFVLLLITYGIMTGAFYSVSTLLNQMILTYYEGEEVNAGRIGLTL 377

  Fly   329 VLAGMLGSVVSGIVLDKTHKFKETTLAVYALSMVGMWIFTFTLDTGHIAVVYLTASLLGFFMTGY 393
            |:|||:||::.|:.||.|..:|:|||.||.||.:||.|||||||..:|.:|::|..:||||||||
Human   378 VVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFIGMVIFTFTLDLRYIIIVFVTGGVLGFFMTGY 442

  Fly   394 LPVGFEFGAELTFPEPEGTSSGLLNASAQTFGICFTLFYSELFTTFGDIAANITMAVMLIVGTII 458
            ||:||||..|:|:||.|||||||||||||.|||.|||...:|.:.:|..|.||.:.|.:.:|.|:
Human   443 LPLGFEFAVEITYPESEGTSSGLLNASAQIFGILFTLAQGKLTSDYGPKAGNIFLCVWMFIGIIL 507

  Fly   459 TAITQSDLRRQNAQV 473
            ||:.:|||||.|..:
Human   508 TALIKSDLRRHNINI 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisT	NP_610301.1	MFS_FLVCR_like	55..461	CDD:340956	214/406 (53%)
FLVCR1	NP_054772.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52
		MFS_FLVCR1	106..512	CDD:341013	215/408 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	535..555