DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1358 and C09D4.1

DIOPT Version :9

Sequence 1:	NP_001188873.1	Gene:	CG1358 / 35697	FlyBaseID:	FBgn0033196	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001020991.1	Gene:	C09D4.1 / 172203	WormBaseID:	WBGene00015632	Length:	586	Species:	Caenorhabditis elegans

Alignment Length:	506	Identity:	239/506 - (47%)
Similarity:	323/506 - (63%)	Gaps:	36/506 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LKHSAGGAGENSETFIATSKSTDMITPK------EKEGKGLKVAGG--HNPPAEGY--------- 50
            |..:.|.:..:|.:...||:.::..:.:      :||.|.:::.||  .|..|.|.
Worm    70 LVRARGSSSAHSCSAATTSQQSNRQSKEHRIGGIKKEEKPIEMGGGSSENGGANGCSNGDNHHVL 134

  Fly    51 ----------KVYARRWAVLILFVFYSSSNAMQWIQYTIINNIITRYYGISDKWVDWTSMIYMIL 105
                      ||:.:||.:|::|:|.|.||..|||||:||.|||:.||.:|.:.|||||||||:.
Worm   135 LMEKQEKIEPKVFRKRWVILVIFMFLSGSNGAQWIQYSIIANIISDYYKVSFQAVDWTSMIYMLT 199

  Fly   106 YIPLIFPGSWFLDKVGLRITALVGIVGTCVGAWIKVFSVDPSLFYVSFIGQSIVALAQVCILSLP 170
            ||....|.:|.|||.|||::.|:|.:|.|||||||:.|..|..|:|:|:||:||..:|:..|.:|
Worm   200 YILFFIPAAWLLDKWGLRLSVLLGALGNCVGAWIKLLSTHPDSFWVTFVGQTIVGASQMFTLGIP 264

  Fly   171 ARLAAVWFGPDQVSSATSVGVFGNQLGVAVGFVLPPMLVPNSPDLETVGSDLQMMFYLVAGLTSI 235
            .||||||||||:||.|.::||||||||:||||||||::|.|. .:|.|..||..:|...|.|.:.
Worm   265 PRLAAVWFGPDEVSRACALGVFGNQLGIAVGFVLPPLIVSNG-SVEHVTYDLNTLFLGSAVLNTS 328

  Fly   236 LLVLMVIFFQDKPPTPPSAAQEAAQLLESSEAEQVSFMQSLKNLMTNRNFIFLLLSYGINVGVFY 300
            :|.|::.||..:|..|||.||..|  ||....:. :|..:|:.|||:|:|:.|.::||||.||||
Worm   329 ILALVICFFTARPAVPPSLAQVNA--LEEKTFDN-NFWGTLRKLMTSRDFVILFITYGINTGVFY 390

  Fly   301 AISTLLNPVVLKYYPGHEVDAGRIGLSIVLAGMLGSVVSGIVLDKTHKFKETTLAVYALSMVGMW 365
            ||||||:.:||..||......|.:||.||:|||.||||.|.:|||..|||.||:.:|..|.|||.
Worm   391 AISTLLSQMVLSVYPNETETVGYVGLLIVVAGMAGSVVGGFILDKFKKFKLTTIMIYLFSFVGML 455

  Fly   366 IFTFTLDTGHIAVVYLTASLLGFFMTGYLPVGFEFGAELTFPEPEGTSSGLLNASAQTFGICFTL 430
            .||.|:|...:.:|::.|:|||||||||||:||||.||:|:|..|||:|||||||||.|||..|.
Worm   456 SFTLTIDLDSMVLVFINAALLGFFMTGYLPIGFEFAAEITYPAAEGTTSGLLNASAQIFGIALTW 520

  Fly   431 FYSELFTTFGDIAANITMAVMLIVGTIITAITQSDLRRQNAQ-----VPAS 476
            ....:...||...:||.|:..|:||||:|...:.||:||.|.     :|.|
Worm   521 LMGIVMHGFGTFTSNIIMSSCLVVGTILTCFIREDLKRQKAHSVQCTIPTS 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1358	NP_001188873.1	MFS_1	62..422	CDD:284993	197/359 (55%)
CG1358	NP_001188873.1	MFS	63..461	CDD:119392	214/397 (54%)
C09D4.1	NP_001020991.1	MFS	154..553	CDD:119392	215/402 (53%)
C09D4.1	NP_001020991.1	MFS_1	154..517	CDD:284993	202/366 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159216
Domainoid	1	1.000	390	1.000	Domainoid score	I407
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134359
Inparanoid	1	1.050	446	1.000	Inparanoid score	I913
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54923
OrthoDB	1	1.010	-	-		D425075at33208
OrthoFinder	1	1.000	-	-		FOG0002624
OrthoInspector	1	1.000	-	-		oto18254
orthoMCL	1	0.900	-	-		OOG6_100662
Panther	1	1.100	-	-	LDO	PTHR10924
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2905
SonicParanoid	1	1.000	-	-		X1725
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940