DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1358 and Flvcr1

DIOPT Version :9

Sequence 1:	NP_001188873.1	Gene:	CG1358 / 35697	FlyBaseID:	FBgn0033196	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	XP_038947431.1	Gene:	Flvcr1 / 108348225	RGDID:	1596541	Length:	568	Species:	Rattus norvegicus

Alignment Length:	489	Identity:	232/489 - (47%)
Similarity:	316/489 - (64%)	Gaps:	37/489 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GGAGENSETFIATSKSTDMITPKEKEGKGLKVAGGHNPPAEG----YKVYARRWAVLILFVFYSS 68
            |||.|..:|.:|..:.|        :.:.|...||.:.|...    ..:..||:.||::|..||.
  Rat    56 GGAPEGPQTLLAAEEET--------QARLLPAGGGEDVPCPARPPRTALSPRRFVVLLIFSLYSL 112

  Fly    69 SNAMQWIQYTIINNIITRYYGISDKWVDWTSMIYMILYIPLIFPGSWFLDKVGLRITALVGIVGT 133
            .||.|||||:.|:|:...:|.:|...::|.||:||:.|:|||||.:|.||..|||:|||:|....
  Rat   113 VNAFQWIQYSSISNVFEDFYQVSPLHINWLSMVYMVAYVPLIFPATWLLDTRGLRLTALLGSGLN 177

  Fly   134 CVGAWIKVFSVDPSLFYVSFIGQSIVALAQVCILSLPARLAAVWFGPDQVSSATSVGVFGNQLGV 198
            |:|||:|..||...||:|:.:||.:.::|||.||.||:.:|:|||||.:||:|.:..|.|||||.
  Rat   178 CLGAWVKCGSVKQHLFWVTMLGQILCSVAQVFILGLPSPVASVWFGPKEVSTACATAVLGNQLGT 242

  Fly   199 AVGFVLPPMLVP--------------NSPDL--------ETVGSDLQMMFYLVAGLTSILLVLMV 241
            ||||:|||:|||              ||.||        :.:..::.:|||..|.:::.|..|.|
  Rat   243 AVGFLLPPVLVPKTQNNNTGLLADTQNSTDLLDDTQNSTDLLADNISIMFYGTAFVSTFLFFLTV 307

  Fly   242 IFFQDKPPTPPSAAQEAAQLLESSEAEQVSFMQSLKNLMTNRNFIFLLLSYGINVGVFYAISTLL 306
            |.|:::|..|||.||  |.|.:|..|| .|:..|:.||..|..|:.||:||||..|.||::||||
  Rat   308 IAFKERPLLPPSQAQ--AVLRDSPPAE-YSYKTSICNLFRNVPFVLLLISYGIMTGAFYSVSTLL 369

  Fly   307 NPVVLKYYPGHEVDAGRIGLSIVLAGMLGSVVSGIVLDKTHKFKETTLAVYALSMVGMWIFTFTL 371
            |.::|.:|.|.||:||||||::|:|||:||::.|:.||.|..:|:|||.||.||.|||.||||||
  Rat   370 NQIILTHYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFVGMVIFTFTL 434

  Fly   372 DTGHIAVVYLTASLLGFFMTGYLPVGFEFGAELTFPEPEGTSSGLLNASAQTFGICFTLFYSELF 436
            ..|:|.||:.|..:||||||||||:||||..|:|:||.|||||||||.:||.|||.|||...:|.
  Rat   435 KLGYIIVVFFTGGILGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNTAAQIFGILFTLAQGKLT 499

  Fly   437 TTFGDIAANITMAVMLIVGTIITAITQSDLRRQN 470
            |.:...|.||.:...:.||.|:||:.:|||||.|
  Rat   500 TDYNPEAGNIFLCAWMFVGIILTALIKSDLRRHN 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1358	NP_001188873.1	MFS_1	62..422	CDD:284993	193/381 (51%)
CG1358	NP_001188873.1	MFS	63..461	CDD:119392	210/419 (50%)
Flvcr1	XP_038947431.1	Herpes_glycop_D	<17..98	CDD:421518	11/49 (22%)
Flvcr1	XP_038947431.1	MFS	99..526	CDD:421695	215/429 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	414	1.000	Domainoid score	I647
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	466	1.000	Inparanoid score	I1474
OMA	1	1.010	-	-		QHG54923
OrthoDB	1	1.010	-	-		D425075at33208
OrthoFinder	1	1.000	-	-		FOG0002624
OrthoInspector	1	1.000	-	-		otm45035
orthoMCL	1	0.900	-	-		OOG6_100662
Panther	1	1.100	-	-	O	PTHR10924
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1725
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980