Protein Alignment HisT and slc49a3

DIOPT Version :10

• Sequence 1: NP_610301.1
• Gene: HisT / 35697
• FlyBaseID: FBgn0033196
• Length: 482
• Species: Drosophila melanogaster
• Sequence 2: NP_001018423.1
• Gene: slc49a3 / 103908782
• ZFINID: ZDB-GENE-050522-300
• Length: 474
• Species: Danio rerio
• Alignment Length: 498
• Identity: 136/498 - (27%)
• Similarity: 221/498 - (44%)
• Gaps: 70/498 - (14%)

  Fly    11 GENSET--FIATSKSTDMITPKEKEGKGLKVAGGHNPPAEGYKVYARRWAVLILFVFYSSSNAMQ 73
            ||::||  .|.:|.:.|...|..:             .|..:.||.|||.:|.:....:.||||.
Zfish     3 GESAETEPLIQSSSAADRPDPAAE-------------AAARFTVYRRRWFILSVLCLLNCSNAMA 54

  Fly    74 WIQYTIINNIITRYYGISDKWVDWTSMIYMILYIPLIFPGSWFLDKVGLRITALVGIVGTCVGAW 138
            |:.:..:.....:...:|...|:|.|:::::..:...|...|.||.:||| .:|:|      .:|
Zfish    55 WLTFAPVAGQSAQLLCVSLPLVNWLSLVFVLAAVVCSFSSMWVLDTLGLR-CSLIG------SSW 112

  Fly   139 IK----------VFSVDP--SLFYVSFIGQSIVALAQVCILSLPARLAAVWFGPDQVSSATSVGV 191
            :.          |.||.|  ::|.|...||::.||||..::..|.:|||:||...|.::|..:..
Zfish   113 LNACGCVLRVCGVLSVTPQWAVFAVVMCGQTLCALAQPLVIFAPTKLAALWFPDHQRATANMLAS 177

  Fly   192 FGNQLGVAVGFVLPPMLVPNSPDLETVGSDLQMMFYLVAGLTSILLVLMVIFFQDKPPTPPSAAQ 256
            ..|.:|:.:..:|.|::|..|.||     .|.::.|.:....:.||..:.| .|..||||.||:
Zfish   178 MANTVGLLLANLLSPLIVSYSGDL-----FLLLLIYSIPAAVACLLATLGI-HQAVPPTPASAS- 235

  Fly   257 EAAQLLESSEAEQVSFMQSLKNLMTNRNFIFLLLSYGINVGVFYAISTLLNPV--VLKYYPGHEV 319
                   ||.:....|:|.::.|:.||.:..|||.:|..:|:|...||||..:  |..|..|.
Zfish   236 -------SSSSASEPFLQGIRQLLRNRAYWILLLCFGSGIGIFTCFSTLLEQILCVKGYSNGF-- 291

  Fly   320 DAGRIGLSIVLAGMLGSVVSGIVLDKTHKFKETTLAVYALSMVGMWIFTFT--LDTGHIAVVYLT 382
             ||..|...::.|:.|:.:..:.:|::.||.|.......|:.|....|...  |....:.:| |.
Zfish   292 -AGVCGAVSIVCGVAGAFLLSLYVDRSKKFMEVMKICMCLTSVSCSAFAVVSQLPAQSVLLV-LV 354

  Fly   383 ASLLGFFMTGYLPVGFEFGAELTFPEPEGTSSGLLNASAQTFGICFTLFYSELFT--------TF 439
            ....|.|.....|||.|...|.|.|..|.||:||:..|.|.....:.|....|.|        ..
Zfish   355 CCCFGLFGYSVYPVGMELSVETTHPLGEATSAGLIFTSGQIQAALYLLLLQALATPTHSPTSVCA 419

  Fly   440 GDIAANITMAVMLIVGT------IITAITQSDLRRQNAQVPAS 476
            .|.:.|.|:.|:::.|.      :......::.||..|:..::
Zfish   420 ADTSLNWTVPVLVMAGVCAISSCVFVVFFHTEYRRLRAEADSA 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisT	NP_610301.1	MFS_FLVCR_like	55..461	CDD:340956	122/435 (28%)
slc49a3	NP_001018423.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		6/16 (38%)
		MFS_MFSD7	36..448	CDD:340957	122/436 (28%)