Protein Alignment scra and Anln

DIOPT Version :10

• Sequence 1: NP_724582.1
• Gene: scra / 35696
• FlyBaseID: FBgn0261385
• Length: 1239
• Species: Drosophila melanogaster
• Sequence 2: XP_038938195.1
• Gene: Anln / 363031
• RGDID: 1561367
• Length: 1134
• Species: Rattus norvegicus
• Alignment Length: 1331
• Identity: 344/1331 - (25%)
• Similarity: 535/1331 - (40%)
• Gaps: 305/1331 - (22%)

  Fly     1 MDPFTQHMLEKAEQRSRALGISNASKFPLVECSVPSSSATSASGGDAGVLAPRSRSPGGQSAASG 65
            |||||:.:||:...|...|....|.:        |:::|.||.....| ..|.|.:...|.....
  Rat     1 MDPFTEKLLERTRARRENLQRKMAER--------PTAAARSAPHAKRG-REPLSEASNQQQPLLA 56

  Fly    66 GGKVVTLGKATLEASPAK-------PLRHYTAVNKENLDMGIEINITTDKPIGVQVEIQEQEVTD 123
            ||:    .|:..:.||:|       .:......|||.:|..   ...:.||...|::........
  Rat    57 GGE----EKSCTKPSPSKKRCSDKIEVEASDLENKEPVDAA---KPCSPKPAPRQMKPPAPAAIS 114

  Fly   124 DEEQAEGGALNPLLEAEPVNQPLARLRDTS--RSRLQRMGALYSN-----TDDLSSPIHRTEGQF 181
            |...|....|:           ..:...||  ::|:|::.....:     |||:|...|     |
  Rat   115 DSVAAPASLLS-----------TGKASTTSSVKTRMQKLAEQRRHWDSEITDDVSESSH-----F 163

  Fly   182 HVTTGEEEDCG------NRSSRQPKQRLGKLAALADTINQWEDDTSHHEV-HRLLEAPPPKPHLS 239
            .....||:...      :.:|..|..|.|:||.||.||..||||.|:... ...::..|....||
  Rat   164 SPMPSEEKPASPSKPPVSNASATPVGRRGRLANLAATICSWEDDVSYSSAKQNSVQEQPGTACLS 228

  Fly   240 SRRAEKGPAPLPPKKDEVDEASRTKQ------LKWDPKVLSSLEAQG--FQRRESSTIKHTYDYA 296
            ...:..||:..........||:...|      :|.||   :|..|.|  .:...||.:|.:   :
  Rat   229 KSSSASGPSASINSSSVQQEATCCSQRDGNASVKKDP---TSNAADGPLLKASVSSPVKAS---S 287

  Fly   297 KQEEAAP----ASKVEDAVLTAKPPVPQKSTTVSQVAKNFASSAPAPKPAPAPAVSVKSGLVSGR 357
            ....:||    ..:|:...|..|...|.|    ::|.|      |..||..:.|:..|.|
  Rat   288 SPVRSAPFITRNCEVQSPELLHKTVSPLK----TEVLK------PCEKPTLSQALQPKEG----- 337

  Fly   358 AALFENKGTGGQSQGLRNQKDPCELSLKERMKLFETGNNKAMLPMAPIGSAPSITQIRAEEVKQH 422
                .||....|||    .||          ||...|..         |..|.:.:. .|..::|
  Rat   338 ----ANKEVCLQSQ----SKD----------KLATPGGR---------GIKPFLERF-GERCQEH 374

  Fly   423 LAAMHPVTAAAATT--VVAATKPKQENKLRDKVAALVANAQSSAETRIKDIDRQRQEDMQIISNR 485
             :...|...|...|  :...||..||...:.       |..||.....:.:.::|::::..:..|
  Rat   375 -SKESPTCRAFHRTPNITPNTKAIQERLFKQ-------NTCSSTTHLAQQLKQEREKELACLRGR 431

  Fly   486 FNKQKELFDNQPSDSSVAAQARPPAPAPSRVVRPMPPPPPPPIAALSPGLASSKRRSPGDAPTTD 550
            |:| ..|:..:..:.|.:.|..     ..:.|.....|             ..|.:.....|:|
  Rat   432 FDK-GSLWSAEKDEKSRSKQLE-----TKQEVHCQNSP-------------LKKHQIVSGTPST- 476

  Fly   551 EDSKRARKSHSDRLYPALSDLDSSGDNCCAAETASATDDSHQQDEEETESCMDESDDQSQT---- 611
                    |.||::                |||.:|...|..:....|||.|.:|.....|
  Rat   477 --------SVSDKV----------------AETPTAVKISGTEPAGSTESEMTKSSPLKITLFLE 517

  Fly   612 EDSSAGMCNGSLGREIMSAVQRNEVEMQQQQTGKKTVRYADQDMYYDDSSLNSSQVSAGIDDYLD 676
            |:.|            :......|||       :||....:.:|..||..:|||:|   |:|...
  Rat   518 EEKS------------LKVASDPEVE-------QKTEAVHEVEMSVDDEDINSSKV---INDIFS 560

  Fly   677 EALVE---DYGSTQDDQ----SDSGDEQ----NASRLSLGSKGTTASNSFSFRKNPASICTPIEE 730
            :.|.|   |...:|::.    ::|.:||    |.|.:||.:.........:.:.   .|.:|
  Rat   561 DVLEEGELDVEKSQEEMDQVGTESSEEQEDVLNISSMSLLAPLAQTVGVVNLQN---VISSP--- 619

  Fly   731 HHEMEMDLQTPLLSGAQP-----VKSELSVNQDNDNLVT----LVHTVSFYRRQQSANSSNSTPV 786
                |::|:...||...|     .::.:...:..|:|.:    |::::..||.|:..
  Rat   620 ----ELELRDSSLSAPSPKPGKFQRTRVPRAESGDSLSSEDRDLLYSIDAYRSQRFK-------- 672

  Fly   787 RKICREQQVMRSALAGDCHAKHRLEYDSPQQSDYVAAATDIADQTDEDDEEMQNAREVNDASQAQ 851
                                    |.:.|.....:....|:..:..|.:.....  :||    .:
  Rat   673 ------------------------ETERPSIKQVIVRKEDVTSKLSEKNGVFSG--QVN----IK 707

  Fly   852 DKIKKLLSEVCKQQQVIGQASQALNLCAATVEFSGSTESVEGERYLLLATHRRQACLDEVQRLRV 916
            .|:::|.:::..||.||.|||||||.|.......||.|..|.||.||:||.:|...:||:.:|:.
  Rat   708 QKMQELNNDINLQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATEKRALLIDELNKLKS 772

  Fly   917 ENSIR--------PVGAPKEKGLLTVKDITIPLRQEYVRKMAS--NNINGHHLVCLLKYNEHVLA 971
            |...|        ..|....||.:|:.:|.:||:.|:|...|.  .:.|.::|:.|....|.::|
  Rat   773 EGPQRRNKTAVASQSGFAPSKGSVTLSEICLPLKAEFVCSTAQKPESSNYYYLIMLKAGAEQMVA 837

  Fly   972 TKTVPTMPGLL--SVKFPDVLQLNNVYADFRITLEIYGMLAQRDQLPHELKYHINLNKKGGIKTP 1034
            |....|...|.  ::.||....||:|..||.|.:|:|.::.::|....|.|...:.:|   ..||
  Rat   838 TPLASTANSLSGDALTFPTTFTLNDVSNDFEINVEVYSLVQKKDSSGPEKKKKASKSK---AITP 899

  Fly  1035 KK-------KGGENRLVMPPVQSPAGPHVVRTPQLVQYGFAIFSLREIQRTTWTLTQV------- 1085
            |:       |...:..||   .||.|...|||......|....||..:..|.:.|.::
  Rat   900 KRLLTSITSKSSLHASVM---ASPGGLSAVRTSNFTLVGSHTLSLSSVGDTKFALDKINFDVREQ 961

  Fly  1086 --LG---------VSPLEGVVHMKVNCELSVSVEYKGFLTMFEDISGFGAWHRRWCYLNGSVINY 1139
              ||         :|||||.:.:|::|:::.:||.|||||:|||:|||||||||||.|:|:.|:|
  Rat   962 ELLGYLFQEKVPFLSPLEGHICLKISCQVTSTVEEKGFLTIFEDVSGFGAWHRRWCVLSGNCISY 1026

  Fly  1140 WKYPDDEKRKTPMGSIDLNSCTSQKVTTAPRDICARLNTMLLECERPALETDQESLIIVPNGRTT 1204
            |.|||||:||.|:|.|:|.:|.|.::..|.|:.|||.||:.|...||..|.|:|:|:........
  Rat  1027 WTYPDDERRKNPIGRINLANCISHQIEPANREFCARRNTLELITVRPQREDDRETLVSQCRDTLC 1091

  Fly  1205 TVRHLLSADTKEEREEWCAYLNKALTLLRAW 1235
            ..::.|||||||||:.|...||:.:..:|.|
  Rat  1092 VTKNWLSADTKEERDLWMQKLNQVIVDIRLW 1122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scra	NP_724582.1	Anillin_N	<195..227	CDD:435074	15/32 (47%)
		MSCRAMM_ClfA	<549..713	CDD:468110	42/178 (24%)
		Anillin	929..1076	CDD:462393	46/157 (29%)
		PH_anillin	1106..1233	CDD:269964	65/126 (52%)
Anln	XP_038938195.1	PHA03307	26..>200	CDD:223039	44/205 (21%)
		Anillin_N	135..221	CDD:435074	25/90 (28%)
		Anillin_N	418..483	CDD:435074	15/108 (14%)
		Anillin	792..945	CDD:462393	46/158 (29%)
		PH_anillin	993..1120	CDD:269964	65/126 (52%)