Protein Alignment scra and ani-1

DIOPT Version :9

• Sequence 1: NP_724582.1
• Gene: scra / 35696
• FlyBaseID: FBgn0261385
• Length: 1239
• Species: Drosophila melanogaster
• Sequence 2: NP_499624.2
• Gene: ani-1 / 176672
• WormBaseID: WBGene00013038
• Length: 1159
• Species: Caenorhabditis elegans
• Alignment Length: 1315
• Identity: 274/1315 - (20%)
• Similarity: 469/1315 - (35%)
• Gaps: 365/1315 - (27%)

  Fly   113 QVEIQEQEVTDDEEQAEGGALNPLLEAEPVNQPLARLRDTSRSRLQRMGALYSNTDDLSSPIHRT 177
            ::.:::.|::.:.|.|:        |..||...:..::....|..:..|:.....|..|:|:|
 Worm    11 RIRVRQAEMSGEGEVAK--------ENGPVTSKITSVKQEVASPTKVFGSSSKCNDGPSTPVH-- 65

  Fly   178 EGQFHVTTGEEEDCGNRSSRQPKQRLGKLAALAD-TINQWEDDTSHHEVHRLLEAPPPKPHLSSR 241
               ||             .::||:....:...|: ::|.::|.|
 Worm    66 ---FH-------------PQEPKETTPNMKENAENSLNSFKDAT--------------------- 93

  Fly   242 RAEKGPAPLPPKKDEVDEASRTKQLKWDPKVLSSLEAQGFQRRESSTIKHTYDYAKQEEAAPASK 306
                           |:|:|..|..::      |:.||.....|       |||..|     .:|
 Worm    94 ---------------VNESSSKKTSRF------SMLAQEIDEYE-------YDYQSQ-----YNK 125

  Fly   307 VEDAVLTAKPP-------------VP-----QKSTTVSQVAKNFASSAPAPKPA----------- 342
            .::|.:..:.|             .|     .||..|:      .||..||:.|
 Worm   126 PKEAYMKGRSPRMSIGETRPAVLCTPAGAQAMKSPNVA------VSSKSAPEIALGMSDFEARRI 184

  Fly   343 --PAPAVSV-----KSGLVSGRAALFENKGT---GGQSQGLR-------------NQK------- 377
              ..|.|:|     :|.:.||.:....|..:   ||.::.:.             ||.
 Worm   185 KFAQPIVNVNYLPNESSIFSGGSGSSVNDQSTVLGGSAEMMNVTTSSLSCGELSMNQHITHENTI 249

  Fly   378 ------DPCELSLKERMKLFE--------------------TGNNKAMLPMAPIGSAPSITQIRA 416
                  |..|..|:||.::..                    |.::.:...:..|..|...|....
 Worm   250 INAQSCDNREAILRERQQVSNEEYGPHTFMRKKVPKEASSATSSSSSTTTLTTISGASGSTTSGI 314

  Fly   417 EEVKQHLAAMHPVTAAAATTVVAATKPKQENKLRDKVAALVANAQSSAETRIKDIDRQRQEDMQI 481
            ....|. :|....|....|:....||....|     :.|||:   ||.:...|||.|.....:..
 Worm   315 SNAPQD-SASTKTTTNTFTSSYLLTKTSNNN-----INALVS---SSPKPFSKDIGRSMFSPVHF 370

  Fly   482 ISNRFNKQKEL------------------------FDNQPSDSSVAAQARPPAPAPSRVVRPMPP 522
            .....:..|.|                        |:.:...||.|....||||..:      |.
 Worm   371 TPKSTSSPKTLSESIFSPSKSAAVEGSIATTRRLQFEEKLKKSSSANVTAPPAPTSA------PV 429

  Fly   523 PPPPPIAALSPGLASSKRRSP-------------------GDAPTTDEDSKRARKSHSDRLYPAL 568
            |.|..:|.|:|.:|.....:|                   ..||...:...|. :|::..:..|.
 Worm   430 PTPRHVAPLAPTVAQQSHLTPNHRHAAQQKKHLFPVVGIVATAPIPVQTQWRG-QSNTPVVQGAR 493

  Fly   569 SDLDSSGDNCCAA-------------ETASATDDSHQQDEEE-----TESCMDES------DDQS 609
            :|..::|:.....             |.:|||......|..|     |...|.||      ..:|
 Worm   494 ADEKTAGNEPPVGAGVGKLKNLKSRWEFSSATGTPIHPDATEDSLIATAIKMKESAIPKQLGHRS 558

  Fly   610 QTEDSSAGMCNGSLGREIMSAVQRNEVEMQQQQTGKKTVRYADQDMYYDDSSLNSSQVSAGIDDY 674
            :.:..||            |::..............|:.||..::   :|....:.:.:.|.|
 Worm   559 ERKGPSA------------SSLYSQGARSNTASPASKSTRYEQEE---EDDVFEAPEFNDGGD-- 606

  Fly   675 LDEALVEDYGSTQDDQSDSGD-EQNASRLSLGSKGTTAS-------NSFSFRKNPASICTPIEEH 731
                ::.:.|..|:::.|:.. ..||.....||...|.|       ......:.||.:   |||.
 Worm   607 ----VISEDGILQEEEEDTSKFIDNAFGFMEGSGAGTPSPYREPPLQRLEKNRPPAEV---IEEE 664

  Fly   732 HEMEMDLQTPLLSGAQPVKSELSVNQDNDNLVT--------------LVHTVSFYRR-QQSANSS 781
            .|.|.:        ::|.:.|   .:::|:..|              |.::|||||: |:..|..
 Worm   665 TENEDE--------SEPYEPE---EEEDDDATTQFPVPERSRKSSSQLAYSVSFYRKIQRDRNEE 718

  Fly   782 NSTPVRKICREQQVMRSALAGDCHAKHRLEYDSPQQSDYVAAATDIADQTDEDDEEMQNAREVND 846
            :||              .|||...:  ::...:|..|..:.:...:...|   ......||.|..
 Worm   719 SST--------------VLAGPVIS--QISPSAPPMSSSLTSQQKLRQLT---TGPANGARIVES 764

  Fly   847 ASQAQDKIKKLLSEVCKQQQVIGQASQALNLCAATVEFSGSTESVEGERYLLLATHRRQACLDEV 911
            |..|.|:||:.:.   .::|::.|:.:|:.|......|.||.|..|.:..:|....:.:|.|.|.
 Worm   765 AKDAHDRIKRAIQ---VEEQLVAQSKRAMILARDKPSFRGSREEFEAQWAMLRHVEKHRALLTEY 826

  Fly   912 QRLRVENSIRPVGAPKEKGLLTVKDITIPLRQEYV-RKMASNNINGH--HLVCLLKYNEHVLATK 973
            .||: .:..|.:..|  :|.:||..:::.:.::|| ..:||:..:..  :...:|:|.|.|..:|
 Worm   827 DRLK-RDGPRIIDGP--RGTITVSQLSVNMARDYVSANIASSKKSDEVFYFAAILRYGEQVDVSK 888

  Fly   974 TVPTMPGLLS---VKFPDVLQLNNVYADFRITLEIYGMLAQRDQLPHELKYHI-NLNKKGGIKTP 1034
            .|.:..||..   ::||..|.|..:..|||.|:||||..:.|:...||.||.: |...|...:..
 Worm   889 MVTSDGGLNRRGVLEFPVPLMLTGIPPDFRATVEIYGQRSMRESTSHEDKYKLKNSTFKAKTRNT 953

  Fly  1035 KKKGG------ENRLVMPPVQSPAGPHVVRTPQLVQYGFAIFSLREIQRTTWTLTQVLGVSPLEG 1093
            ...||      ::..|.|...|.:.........|:  |...|.:....:..:.::..  |.||||
 Worm   954 FLGGGSTSSANQSLFVDPAASSSSTSSTTSNFNLL--GTFSFDINCPGKHLYNMSHT--VYPLEG 1014

  Fly  1094 VVHMKVNCEL--SVSVEYKGFLTMFEDI-SGFGAWHRRWCYLNGSVINYWKYPDDEKRKTPMGSI 1155
            :..|||..:.  ...:.|.|||:|::.. .|.|:|.|.||.|....:.:||.|:||..|.....:
 Worm  1015 ITQMKVRKQAIDGADITYHGFLSMYQRTGEGLGSWTRYWCALENGEMKFWKQPEDEGTKGYTALM 1079

  Fly  1156 DLNSCTSQKVTTAPRDICARLNTMLLECERPALETDQESLIIVPNGRTTTVRHLLSADTKEEREE 1220
            ||::|...:..:...|||...|:..::...|.::|..      |.| ...:|.:|:|||.::.:.
 Worm  1080 DLSTCCRSEGASVVEDICPFPNSFHIDVWAPKMDTSD------PRG-IERLRVMLAADTAQDLQT 1137

  Fly  1221 WCAYLNKALTLLRAW 1235
            |.:.:|.....|..|
 Worm  1138 WLSLINSTSKQLCTW 1152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scra	NP_724582.1	Anillin_N	153..227	CDD:292637	14/74 (19%)
		Anillin	929..1076	CDD:285397	42/159 (26%)
		PH_anillin	1106..1233	CDD:269964	36/127 (28%)
		PH	1107..1229	CDD:278594	36/122 (30%)
ani-1	NP_499624.2	DUF4654	420..517	CDD:292184	19/103 (18%)
		Anillin	840..995	CDD:285397	43/158 (27%)
		PH_anillin	1029..1150	CDD:269964	36/127 (28%)
		PH	1030..1147	CDD:278594	36/123 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I6257
eggNOG	1	0.900	-	-		E1_KOG3640
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110462at33208
OrthoFinder	1	1.000	-	-		FOG0003560
OrthoInspector	1	1.000	-	-		oto19536
orthoMCL	1	0.900	-	-		OOG6_106902
Panther	1	1.100	-	-	O	PTHR21538
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4027
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.820