Protein Alignment scra and AgaP_AGAP010715

DIOPT Version :9

• Sequence 1: NP_724582.1
• Gene: scra / 35696
• FlyBaseID: FBgn0261385
• Length: 1239
• Species: Drosophila melanogaster
• Sequence 2: XP_311427.4
• Gene: AgaP_AGAP010715 / 1272514
• VectorBaseID: AGAP010715
• Length: 1350
• Species: Anopheles gambiae
• Alignment Length: 1441
• Identity: 603/1441 - (41%)
• Similarity: 800/1441 - (55%)
• Gaps: 303/1441 - (21%)

  Fly     4 FTQHMLEKAEQRSRALGISNASKFPLVECSVPSSSATSASGGDAGVLAPRSRSPGGQSAASGGGK 68
            |.|::||:||:|:.||||:|.|||||.|.:..:....||:|.     :|:.:| ||.:.||...|
Mosquito     4 FFQNILERAEKRAAALGITNTSKFPLSEFNYEADQQGSAAGA-----SPKKKS-GGAAGASPKKK 62

  Fly    69 VVTLGKATLEASPAKPLRHYTAVN-----------------KENLDMGIEINITTDKPIGVQVEI 116
            .|     |.:.|..||....|.|:                 ::|.|:.:||||||.  ..:||::
Mosquito    63 SV-----TKKHSAPKPPPPTTTVSTRTATDGERTTTVDIGGQDNCDLALEINITTS--ANLQVDL 120

  Fly   117 QEQEVTDD---EEQAEGGALNPLLEAEPVNQPLAR--LRDTSRSRLQRMGALYSNTDDLSSPIHR 176
            ..:|:.:|   ::|.|...:. .||.|..|...|:  :||.||::|||:|.|||.|.|||||:||
Mosquito   121 GVKELENDGSVKKQWEHNIVR-ALEGEKENSAEAKSVIRDQSRNQLQRLGTLYSETQDLSSPVHR 184

  Fly   177 TEGQFHVTTGEEEDCGNRSSRQPKQRLGKLAALADTINQWEDDTSHHEV--HR--LLEAPPPKPH 237
            |||:||      ||. .:||.:||.:|.|||.|||:||.|||||||.::  ||  ::.....|..
Mosquito   185 TEGRFH------EDV-KQSSNKPKPKLAKLAMLADSINNWEDDTSHPDITHHRETIVPGRERKSP 242

  Fly   238 LSS--------RRA-------------------EKGPAPLPPK------------------KDEV 257
            :||        :||                   :|.|||.|||                  ....
Mosquito   243 ISSSSTRQQSPKRAGEARTGASGSSAPGTGATPKKYPAPNPPKSILTATQKTGSNGGGEPSSGAA 307

  Fly   258 DEASRTKQLKWDPKVLSSLEAQGFQRRESSTIKHTYDYAKQEEAAPASKVEDAVLTA---KPPVP 319
            .:..:||.||||.||:.:||:||||||||:|.|..||| |:::....:....|.:||   .....
Mosquito   308 GKPVQTKSLKWDQKVMDTLESQGFQRRESTTSKLVYDY-KEDKNGQKTDTYRAPVTASAVSSTSR 371

  Fly   320 QKSTTVSQVAKNFASSAP--------------APKPAPAPAVSVKSGLVSGRAALFENKGTGGQS 370
            :::||.:..|.....|||              |||||        .||||||||:|| |.:|.:.
Mosquito   372 ERNTTQADQADAVKKSAPVSSSSSQPKKVAVGAPKPA--------GGLVSGRAAMFE-KSSGRRQ 427

  Fly   371 QGLR-NQKDPCELSLKERMKLFETGNNKAMLPMAPIGSAPSITQI--RAEEVKQHLAAMHPVTAA 432
            ..|: .||||.|:||||||.:||.....|::|.|..|.:|||.||  :.|..|...:...|::.|
Mosquito   428 SILKPGQKDPAEMSLKERMAIFEKNKGAALVPKAAFGISPSIRQITGQKEGGKSGSSGSGPMSCA 492

  Fly   433 A--------ATTVVAATK-------------------PKQENK-----LRDKVAALVANAQSSAE 465
            |        .|...|::|                   ||.|.|     :|:.|.||:::..:.::
Mosquito   493 AIQGSGFGSITQQAASSKGVAPASPQSKPKVDHDKAAPKVETKATGSAIRNTVEALMSDTSTISQ 557

  Fly   466 TRI-KDIDRQRQEDMQIISNRFNKQKELFDNQPSDSSVAAQARPPAPAPSRVVRPMPPPPPPPIA 529
            :.| ::|.|.||::|:::.|||.|        |:|.|.........|.||      .||.||...
Mosquito   558 SEISEEIRRMRQQEMEMLLNRFTK--------PADMSSDTIEYETQPIPS------APPMPPEGY 608

  Fly   530 ALSPGLASSKRRSPG-----------DAPTTDEDSKRAR---KSHSDRLYPALSDLDS----SGD 576
            ....|...||..:.|           |.....:|.||.|   .:...|:||||||:::    |||
Mosquito   609 LTGSGRKQSKHSAEGNNVHDGTNDSADVMAALDDVKRIRVGPAAKDGRMYPALSDIETTATESGD 673

  Fly   577 NCCAAE-----TASATDDSHQQ----------------DEEETESCMDESDDQSQ------TEDS 614
            .....:     |.|.::.|.:.                ||||.   .||.:|..:      .:|.
Mosquito   674 EGAVGDDYTTATVSGSEGSERAYRTCYGEAEDGERELGDEEED---YDEEEDNERRHFMYSDDDE 735

  Fly   615 SAGMCNGSLGREIMSAVQRNEVEMQQQQTGKKTVRYADQDMYYD--DSSLNSSQVSAG------- 670
            .|.:.|.||||||:.||:.|:         ::|.|...|...::  ..||:.|..|.|
Mosquito   736 EANIANVSLGREILQAVKLND---------RRTSRGRRQSQEWNGVSFSLDRSGASDGTDPLEDS 791

  Fly   671 --IDDYLDEALVEDYGSTQDDQSDSGDEQNASRLSLGSKGTTASNSFSFRKNPA-SICTPIEEHH 732
              ||..|:||||:          :..:|:::.......|.:.:|||||::|:.. ..|..|.|..
Mosquito   792 DLIDACLEEALVD----------EEEEEEDSEAFDTPRKSSVSSNSFSYQKHSGRDRCATINEEE 846

  Fly   733 EME--------------MDLQTPLLSGAQPVKSELSV--NQDNDNLVTLVHTVSFYRRQQSANSS 781
            ..:              ...|...:..:.||:|||.|  ::|:|::||||||||||||||..||
Mosquito   847 SAKDPKSGANKRKSGTPRKSQVGTVDYSSPVRSELQVKPSKDDDDMVTLVHTVSFYRRQQQQNS- 910

  Fly   782 NSTPVRKICREQQVMRSALAGDCHAKHRLEYDSPQQSDYVAAATDIADQTDEDDEEMQNAREVND 846
             .|| ||:.|.....:.|...          .||:      |.|..:..|:|.:
Mosquito   911 -MTP-RKVPRTPVSTKMAATN----------SSPR------AGTSTSTGTEEGE----------- 946

  Fly   847 ASQAQDKIKKLLSEVCKQQQVIGQASQALNLCAATVEFSGSTESVEGERYLLLATHRRQACLDEV 911
             ...|:|:||||.||||||.:|.||||||||||||:||||||||.||||:||:|||||||.||||
Mosquito   947 -FLVQEKVKKLLDEVCKQQTIIAQASQALNLCAATIEFSGSTESAEGERHLLVATHRRQAILDEV 1010

  Fly   912 QRLRVENSIRPVGAPKEKGLLTVKDITIPLRQEYVRKMASNNINGHHLVCLLKYNEHVLATKTVP 976
            ||||||..:||.|||.|||.||||:||:||:|||:||:|::.|:||:|||||||||.||||:|.|
Mosquito  1011 QRLRVEGCLRPPGAPTEKGRLTVKEITLPLKQEYMRKLATDQISGHNLVCLLKYNETVLATQTAP 1075

  Fly   977 TMPGLLSVKFPDVLQLNNVYADFRITLEIYGMLAQRDQLPHELKYHINLNKK----GGIK---TP 1034
            |:||||||:|||||||:||:|||:||:|||||.|.|:.||||:||||.|.||    |..|   ||
Mosquito  1076 TLPGLLSVRFPDVLQLSNVFADFKITMEIYGMPASREVLPHEIKYHIALGKKKTGSGSSKLLHTP 1140

  Fly  1035 KKKGGENRLVMPPVQSPAGPHVVRTPQLVQYGFAIFSLREIQRTTWTLTQVLG-VSPLEGVVHMK 1098
            |.....:||:||||||||||..||:|.|.||||.||||:|||||:|||..:.| .|||:|.|:|:
Mosquito  1141 KGLKSNSRLIMPPVQSPAGPQAVRSPSLTQYGFIIFSLKEIQRTSWTLNPISGCASPLDGTVNMR 1205

  Fly  1099 VNCELSVSVEYKGFLTMFEDISGFGAWHRRWCYLNGSVINYWKYPDDEKRKTPMGSIDLNSCTSQ 1163
            |||||:|:|:|.|||||:||:||.||||||||.|....|||||||||||||.|:|||||..|::|
Mosquito  1206 VNCELAVTVDYHGFLTMYEDVSGLGAWHRRWCRLQRHTINYWKYPDDEKRKAPIGSIDLQGCSTQ 1270

  Fly  1164 KVTTAPRDICARLNTMLLECERPALETDQESLIIVPNGRTTTVRHLLSADTKEEREEWCAYLNKA 1228
            :|..||||||:||||:|||..|||.:.|.|||.||.:|:||..|:|||||:||||:||||:|||.
Mosquito  1271 RVGVAPRDICSRLNTLLLEFPRPARDDDVESLKIVRHGKTTIERYLLSADSKEERDEWCAHLNKT 1335

  Fly  1229 LTLLRAWGTTH 1239
            |.||:|||.:|
Mosquito  1336 LALLKAWGASH 1346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scra	NP_724582.1	Anillin_N	153..227	CDD:292637	44/75 (59%)
		Anillin	929..1076	CDD:285397	103/153 (67%)
		PH_anillin	1106..1233	CDD:269964	86/126 (68%)
		PH	1107..1229	CDD:278594	84/121 (69%)
AgaP_AGAP010715	XP_311427.4	Anillin_N	161..226	CDD:292637	44/71 (62%)
		Anillin	1028..1182	CDD:285397	103/153 (67%)
		PH_anillin	1213..1340	CDD:269964	86/126 (68%)
		PH	1214..1337	CDD:278594	84/122 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	324	1.000	Domainoid score	I3238
eggNOG	1	0.900	-	-		E1_KOG3640
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H122811
Inparanoid	1	1.050	890	1.000	Inparanoid score	I1167
OMA	1	1.010	-	-		QHG27366
OrthoDB	1	1.010	-	-		D110462at33208
OrthoFinder	1	1.000	-	-		FOG0003560
OrthoInspector	1	1.000	-	-		oto105654
Panther	1	1.100	-	-	LDO	PTHR21538
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4027
TreeFam	1	0.960	-	-
	13	12.940