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Protein Alignment blow and CA3

DIOPT Version :9

Sequence 1:	NP_001163073.2	Gene:	blow / 35694	FlyBaseID:	FBgn0004133	Length:	644	Species:	Drosophila melanogaster
Sequence 2:	NP_005172.1	Gene:	CA3 / 761	HGNCID:	1374	Length:	260	Species:	Homo sapiens

Alignment Length:	280	Identity:	59/280 - (21%)
Similarity:	92/280 - (32%)	Gaps:	94/280 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   397 SVSGELESLGLLNEGDIKVQP--QPSSLHGSISLDFQARVKTVHSELST-----------QLSAA 448
            :..||.:|...|:..||:..|  ||    .|:|.| ....||:.:...|           .:...
Human    22 NAKGENQSPVELHTKDIRHDPSLQP----WSVSYD-GGSAKTILNNGKTCRVVFDDTYDRSMLRG 81

  Fly   449 G--PSPDRLKKAA---KKSYSNGSE---------PEMLSPLTSPVQTPTKDQKKQRKSTTSPQSS 499
            |  |.|.||::..   ..|..:|||         .|:.....:|.....|:..|||
Human    82 GPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQR--------- 137

  Fly   500 PVSKDCDKLARNWFLSRLNKSTG-----LKATNTGSASPTNAKCKQSEKENLLTEAELGEGYDAS 559
                  |.:|......::....|     |.|.:         |.|...||...|:      :|.|
Human   138 ------DGIAVIGIFLKIGHENGEFQIFLDALD---------KIKTKGKEAPFTK------FDPS 181

  Fly   560 ---PGDR----YHGLPGSPPTSPCLKAEAKSKVNMIINQFESSGHLSTMFSVEALAANALASLTS 617
               |..|    |.|...:||...|:       |.:::.:         ..:|.:.....|.||.|
Human   182 CLFPACRDYWTYQGSFTTPPCEECI-------VWLLLKE---------PMTVSSDQMAKLRSLLS 230

  Fly   618 FCESDG----CNNYEPIMPL 633
            ..|::.    .:|:.|..|:
Human   231 SAENEPPVPLVSNWRPPQPI 250

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.