DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vps13 and vps13c

DIOPT Version :9

Sequence 1:	NP_001260781.1	Gene:	Vps13 / 35693	FlyBaseID:	FBgn0033194	Length:	3321	Species:	Drosophila melanogaster
Sequence 2:	XP_021327607.1	Gene:	vps13c / 798746	ZFINID:	ZDB-GENE-070426-4	Length:	3755	Species:	Danio rerio

Alignment Length:	3914	Identity:	1047/3914 - (26%)
Similarity:	1777/3914 - (45%)	Gaps:	880/3914 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVFEAVVADVLNKVLGDYIENLDRNQLKIGIWGGDVVLQNLKIRENALDELDLPVQLIYGYLGKL 65
            ||||::|:|:||:.:|||:||||::|||||||||:|||:|||::||||.|||:|.::..|.:|||
Zfish     1 MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKL 65

  Fly    66 VLKIPWKNLYSQPVIVNIEDLYVLVSPNNNVQYNAEKEAKYEMDLKKAALDALE----------- 119
            .|||||||||::.|:..::.||:||.|...::|:|.||.:|..:.|:..|..:|
Zfish    66 TLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDS 130

  Fly   120 ---------------------------------AARKKELEMDQP---KADAGFAEKLTAQIVNN 148
                                             .::|.|.:.::|   |.|. |||||..|::.|
Zfish   131 QAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDT-FAEKLATQVIKN 194

  Fly   149 LQVQITNVHLRYE-DTTTTGSPFSFGISLHELELYTTDCDWEKCYMAQQASQVFKIANLSCLSAY 212
            |||:||::|:||| |.:....|.:.|::|.||.|.|.|.:|:.|.:.:.|..::|:..|.|..||
Zfish   195 LQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAY 259

  Fly   213 LNCGGQL-YANNKSDLSQQFKTNIACK-ETKPNYNYVLGPISCNAKLKLNMNPELDDPPFEKPKI 275
            .|..|.: |.::...:.::.|..|:.| |....|.|:..||..:|::.:|.|.|::   .:.||.
Zfish   260 WNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVE---LKSPKA 321

  Fly   276 DLTLEMEKLNVGLTNTQFDNLMKLGDAMNRQQLGIPYRKYRPYNIPYKGHARDWWHFAITSILEE 340
            :|.||::.:.:.:|.:|:.:::.|.::::......||||:|| ::|...:||.||.:.|:||||.
Zfish   322 NLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRP-DVPVHRNARQWWKYGISSILEV 385

  Fly   341 EVRKPRESWTWGHIKTHRERCNTYAQKYKEQCLSKKPSAVLTETCRL----------LETELDVF 395
            .||:..:.|.|.:||.||:....|...||.:         ||::.::          ||..||||
Zfish   386 HVRRFNQMWNWTNIKKHRQTLKAYKAAYKVK---------LTQSAKVREDADKQIQELEKGLDVF 441

  Fly   396 NLLLIRQRVNIEIAKQ------REAVPEQKS--GWFSGWGWGGGAKKDDQTTSQKLVEKFEAAMT 452
            |::|.||:|.:|:.:.      ::|..:::|  |:||.:   .|.|:..:....|..|..::.||
Zfish   442 NIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSF---FGKKEGKKEEEDKEPESIDSIMT 503

  Fly   453 SEEKEKMYRAIGYQENAKPTDLPESYEAIRMNFKLIALEVGLYKDERNSSAATKDFHELPSLVLL 517
            .|||.|:|.||||..::....||:.|.|:.:||||::..| .:::|..          :|.::.:
Zfish   504 VEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSV-TFREEPG----------VPEILKV 557

  Fly   518 NFSMATALITQRPAAEAISIIAGMREIKVTGLTRNDYTPLLVESKITDEFNLLEVFFETNPLDKL 582
            .....:..|:|||.|:||.:.|.:....||||.:....|.|:.|....:.:||.|.||.||.|..
Zfish   558 QMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSP 622

  Fly   583 CDQRVKVVARPLQITYDAPTILALINAFQTPGDVTLSKFEDAASTKISNFKERSATGMQYMIDKK 647
            .||.::|.::|::|.|||.|::::...|:|...|.|.....|..:|:...||::|||:.::|:.:
Zfish   623 ADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETR 687

  Fly   648 AVLDVDILLMPNILVVPHKGVYDAGNVSLLVVSMGQVHLSSQPRRESNKLQHLFSAGEDKDEILK 712
            .|||:.|.|.|:.|::|..|.|| |...|::|..|.:.|:|..:....::...||:       |:
Zfish   688 KVLDLRIDLKPSYLLLPKSGFYD-GKSELMIVDFGYLQLNSVDQGGHQQVSASFSS-------LE 744

  Fly   713 TVMENAYDRFTVAVDDVQMLVVRAGEPWQNALAEANSTEMHVLRPVSLKVTAALCVVDNDPRLPN 777
            .:|:.||:|:::.:..||:|..|:||.|::|..|..| ..|:|:|:...:..|.|:||.|.|:|.
Zfish   745 EIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLS-HQHILQPMDFTLQLAKCMVDKDARMPR 808

  Fly   778 IKVDIDLPAILVNVSEDRIFLAIKVATSIPLPEQ-KEPASRLTQTNSR-SSMSISNFINKEVKKI 840
            .||..:||.:.:.:|:.:|...:::..|||||:. ..|.|  :.|..: ..|.:|| ...:|..:
Zfish   809 FKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPS--SPTGKKVLGMPLSN-TRPKVLAL 870

  Fly   841 GPS-------------ASGSSASKDPLLDEIIQYTSLDVNFSLGEINFVLFQSSRK--------- 883
            .|:             .|..|..::.|...:.:.|.:...|   |:..|||:.:|:
Zfish   871 DPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQF---EVKAVLFELTRQAAQEDVVLA 932

  Fly   884 ------------------------------CE------------TSPD------VSIEFLTPD-- 898
                                          ||            ||.|      :.:|::..|
Zfish   933 FSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEEKDVQNQPLHLITSSDKHGSDLLKVEYIKADVN 997

  Fly   899 --------------------------------------GDVLPSQLT------------------ 907
                                                  ...:|.:||
Zfish   998 GPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGK 1062

  Fly   908 ----------------------------------------------------------------- 907

Zfish  1063 TVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVL 1127

  Fly   908 ----------------------------------------------------------------- 907

Zfish  1128 DVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSL 1192

  Fly   908 ----------------ENIQEPIEELPPTPPQQI----------------LSIDIRRLEAHFV-- 938
                            :|.|...|.|.....|..                |::|| ||:|..:
Zfish  1193 LDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDI-RLKAPLIII 1256

  Fly   939 --SKTYESVATVKLG-------------------------DINLRQ---------YDCQDSDMDV 967
              |.|..:...|.||                         ||.|.|         :|....|:::
Zfish  1257 PQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEI 1321

  Fly   968 LD--------------------------------------------------------------- 969
            |:
Zfish  1322 LEPINLELLVKRNLAAAWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEG 1386

  Fly   970 --------------------------------------------------VIYTPKQEN------ 978
                                                              ::...|.:|
Zfish  1387 TKASAKDEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPF 1451

  Fly   979 --------------------SSNYLFTVS--------------CTI-----------------AD 992
                                ::.|:.|:|              |.|                 ||
Zfish  1452 LVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKAD 1516

  Fly   993 KSSPEFSTKYNSTEQLVVANFEVLQIVLHQECLQRIMEVVNNFQRNLDLVLS-STRPRDRMGSIG 1056
            ::.|.|::.|.:|||.:...|..|.::||.|.|...|:.       |...|| |:.|.....|
Zfish  1517 RNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDF-------LSAALSTSSLPSPERES-- 1572

  Fly  1057 GGDGIKRTLNVILEDTEEIMTTDQMKRRKKTRRTHVVETVKVRVIANLDQVG---LVLTGRKRPI 1118
                         :.:|::.||.    .|.|..:...:...:.::.|: |:|   :::..:|..:
Zfish  1573 -------------KKSEDMKTTS----AKSTALSSPSDGDIIDLMVNM-QLGAFNVLVCDQKSNM 1619

  Fly  1119 AEMNVKKFVSSLIIKSSYTEVNIGLKDIQVLDLNPYTIHKNILSIVGKDAFNCQIVIYNKEET-- 1181
            |::.::....||.:|.:.|.:...|:|..|::::..||||..:||||.:.|:..:.:..|...
Zfish  1620 ADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGA 1684

  Fly  1182 --QDYNSDDMKITVDIGCMKIIFLNWFVAGVMNFLNNFTAAQATISQAGAAAAESARQKAMDAYE 1244
              .|.:..|.|:.:::||:::::|:.|...::||.|||..|:..:|.|.|.|||.|.....|..:
Zfish  1685 GYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQ 1749

  Fly  1245 TATRMKLNIRIKAPIIIVPIGSQDRNALLLDLGLLELTNNTVEVAVAEEERLAVIDEIKLQICDV 1309
            .:.|:.::|::|||:||:|..|...||:..||||:.:.|....:.|......||||.:.:|:..:
Zfish  1750 KSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQL 1814

  Fly  1310 KISKIVL-LDGNESTVDEVDAEVGFLSKFNMMNPMSCTLSITRNLSYTWYRDVPELNLSGRLKSI 1373
            |:|:|.: ||.::::           ||  ::.|::..||:.|||:.:||:.:..:.:.|.||.:
Zfish  1815 KLSRISMELDSDQTS-----------SK--LLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPM 1866

  Fly  1374 ELTLFADDYALVMLVLNRNLNEGLEEFPPSEEAPQEAQVRPERRNSRAGR-LSRTVQVSPIRE-K 1436
            ::.|..||.::::.:|..|:.|..:  ..|:.|.::..|....|.:.... |...:..|.::| :
Zfish  1867 KVALSQDDLSVLLRILMENIGEASD--IQSDTALRQENVLVRARTATGSEILEEKLSESKLKETE 1929

  Fly  1437 IHESIKFNFQFDGVVINL---------MEGEGAGLARFGIYFLSVKGTKLDNGTLSTSVVLCNIQ 1492
            :.||::|:|..:.:.:.|         :..|.:.|..|.:..:.:.|..|:||.:..|.:|....
Zfish  1930 LLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCT 1994

  Fly  1493 MDDMRSNSKSQIRQYLSRKDWVQPKLDTDEIIDACYNERNFMVDVTAIIKEDDTFAEVRVRGFDL 1557
            :||.||..:....:.|.|:|    :..::.:||..|::......|.|::::             |
Zfish  1995 LDDRRSGIQRVTSRMLGRRD----EETSEPMIDVTYSQSVDERSVVAVLQK-------------L 2042

  Fly  1558 IVC--IDFLLKLTTFL-----TLPPEENPRESVYIKPAPVSETARDTKHSIRSSAILAAQELVPV 1615
            .:|  ::|||.:..|.     |.||.:..:.:    ..|:...:....|:...:..|::
Zfish  2043 YLCASVEFLLAVADFFVQALPTSPPTQREKTN----QLPLKYVSEPKIHTEPKAVYLSS------ 2097

  Fly  1616 ESSSHEVPNRKMNLILHIDEPDIILVENLEDLNTSCIIFNAQVHLNYRSINDKQIVNGQIDALKM 1680
                  ||.::..|...:.:|:::.|.||...:...::.:.|...:..|....|.:...:.:||:
Zfish  2098 ------VPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKV 2156

  Fly  1681 YMCAFLPERREMTRHYILHPCVISLQGSTPEEEGMHISLKLSDIIINVSPA---TIELLNKAMLS 1742
            ..|.|:....:.....:|.||.:.|:...|....:..|:.:.::|:.:||.   |:..:..||..
Zfish  2157 LACPFIRAEGDKAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAP 2221

  Fly  1743 VSSGTMTKCAIAEESRNYSNLWHQHHFHSRTYWFTKVEQGVD-ALEAEQRSVSTDNEKQ-KTEKC 1805
            .....:::    ::|.:.::||......:..|||.    ||| |.|..:.....|:.|. :|...
Zfish  2222 KPKEELSQ----QKSGDQNSLWSLMSVANANYWFL----GVDTASEVTESFTDVDSSKDGETFGL 2278

  Fly  1806 VIEIPSITLVIESGVGYYTKPLISLDTRITAVFNNWSRSLTAHGSLTLNMNYYNQALAEWEPIIE 1870
            .:::..:||  |||:|:.|.||:..::..:....|||..|:....:||.:||:|:..|.|||::|
Zfish  2279 TVKVVQVTL--ESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLE 2341

  Fly  1871 LNEVIGRNGVREYTPWELKFEMGMEKVQSELEDDAEQQAM------HMNIHSAETLEITLSKTCL 1929
            ..:    ||.|.   |.||.:|....|:.:.....:...|      .:.|.|.:|:.||:||.||
Zfish  2342 RVD----NGKRR---WNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCL 2399

  Fly  1930 GLLSELAEAFSQA----IDQNGLTKPDIVAPYVLENDTGFDV----NLNLR-KGIFTLHEVHRGG 1985
            .:.:.||:|||::    .|.:...|    :|:.:.|..|..:    :.||| .|..||.:||.
Zfish  2400 NVFNNLAKAFSESTASTFDHSLKEK----SPFTIRNALGVALIVQHSANLRVPGSSTLGKVHE-- 2458

  Fly  1986 TPVGANSTLLMVAQSEEVDPSVIKTCTISTGGRAYLQTKDLSTLSEEDSEDYTLYVTIGDINKEI 2050
                     |.|.:|.:::.|            ::.::...|.|..::|..:.|.:.....::..
Zfish  2459 ---------LAVDKSLDLEYS------------SFERSSRQSALQRQESCLFNLSIVPSGYSEIS 2502

  Fly  2051 ALPVSKSDTRFFNLMRSTSHEPWGIISEVKQEYGTTKVNIHGVVSVHNHFTTGLNIYRRNPAPTA 2115
            .:|:.|...|.:|:.:....|...::.::....|...:.:...:.:.|||:....|.:.    ::
Zfish  2503 NIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKY----SS 2563

  Fly  2116 QCFEDIFVGRVRPGEVFHVPLHAIYAESKDLFFSMRG-----YRRSVQGISWASNPSDLNYSHQL 2175
            :....:.||...|.:..||||.|..::   ||....|     ||.|...|:|...   ::.|.::
Zfish  2564 ELGGMVNVGVAEPEKECHVPLEAYRSQ---LFLLPVGPLEKLYRASTTCIAWKEK---VHVSSEV 2622

  Fly  2176 H----CDPT-NTFEPLIMNARRSKSEVYFENTNKYTLLSAFYTIHLRPPLYLRNSLPINIQVSVA 2235
            |    |..| :.|.||::|......::.....:........|.|||.||:.::|.||.:|:..:.
Zfish  2623 HAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLE 2687

  Fly  2236 GCSVRKEDGLDAQSSQRFVDRGYRKEDFLDYGEKPVNSGDVLHLPTVRLASKGKESKSFLVVRLV 2300
            |.:                       |..:..|.  ::.|||:         ...|...:.:.|:
Zfish  2688 GSA-----------------------DIYELQEG--SAADVLN---------SNVSGEIMELILI 2718

  Fly  2301 QYLEKDWSCATEIWDYTDDVITWTFSSYDSEMKVDMDLYVKTENRHGSLMLTLFSPFWMINKTGM 2365
            :|..::|:....|.....:.||..|:. |:...:.:|:.|......|..:|::.||:|:||||..
Zfish  2719 KYQGRNWTGRMRISRDMPEFITICFNC-DTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSR 2782

  Fly  2366 MLTYKSETTSVEVLYHPPEYSGPILFTFRDKLFFDKKKASIRIDNGQWSEKIPLDVAGSVGEVIC 2430
            :|.|::|.|.|:   ||.::...|||:|:.|..|.|.|..:.:....|||...||..||.|.|.|
Zfish  2783 VLQYRAEDTFVK---HPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRC 2844

  Fly  2431 FANNQKYPVGVHNHLTQNSLTKQITFIPFYIVCNKCHFDI---ELQEQSRPADPWLHLEPNEMEP 2492
            ...:..|.|||...::..:||:.:|..|||.:.||..|::   |:|..:..::.|.::...|..|
Zfish  2845 PDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLP 2909

  Fly  2493 LWPRNDTKNNLVVRVDG--KITPAFDFTEVIC-TLLKLEDSKYGGINVDVQTTEGGVYITFTDYK 2554
            .||.:.|: .|.|||.|  ..:.:|.|.:... |||:::  :|||:.|||..::....|:||||.
Zfish  2910 FWPESSTE-KLCVRVVGCESSSKSFFFNKQDSGTLLRMD--QYGGVIVDVNISDHSTVISFTDYY 2971

  Fly  2555 PADAPGLLINHTGKQIV-YHEKGTKNEHILNAKSTIMYAWDDPTGPKMLVFG--TNKEETDLKRD 2616
            ...||.|::|||....| :.::|.:....|.......:|||||.|.:.|.:.  .:..|.||.:|
Zfish  2972 DGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHSGELDLVKD 3036

  Fly  2617 GIGEVIMQDGGKVLWVSFLDGLQRVLLFTENESIANRTESTASLQSITQSIDLRIHGIGLSVINN 2681
            ..|:.......::.|||||||.||||:|||:..|..:......|:...|.:::.:..:|||:|||
Zfish  3037 ECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINN 3101

  Fly  2682 ETGLDILYLGVTSSGIIWESKKVTKNRFKELTINENALLEIEYQKYLVHKSVNDVQTYKLDNKFP 2746
            :...:|.|:|:||||::||.:  .|||:|........|||..||.: ::||  |.....|:....
Zfish  3102 DIRQEIAYVGITSSGVVWEMR--PKNRWKSFNHKNIGLLEKAYQNH-INKS--DPGWTMLETGIE 3161

  Fly  2747 IDFDL--MILKKTVERNLRRSFYPAIWLSRKSSPFQSQLHVKINRIQVDNQFLDPIFPVVLAPIP 2809
            ::|..  |::::.....:||:|.|.|.:..|.||.|..|..::..:|||||....|||.|..|:|
Zfish  3162 VNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVP 3226

  Fly  2810 PPKSVASTTSLKPFIECSMVQRIMPNSTVRQFKYARILIQEFLFKVDLNFLTAIAEMF---AKEV 2871
            .|||:...:..||||:.|::.|...:|.|.||||...|:||...|:|..||.||..:|   ...:
Zfish  3227 LPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSL 3291

  Fly  2872 SDEAAAKQFRQDVESIELPLSAFFEEHSLEEQK--SFYDNLHLGPLKIHVSFSMAGSDTKALPG- 2933
            ..:...|..::|:::::..|.    |.||.:..  ||:::.|:.|:|:|:|.|:..|..::..|
Zfish  3292 DSKKKNKLIQKDLDALQAQLM----ESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGD 3352

  Fly  2934 -----FLGSLVQGVGVTLTDVNDVVFRLAFFEREYQFFSQKQLINEITSHYTGQALKQLYVLVLG 2993
                 .:..|::.:|.|||||:|::|:||:||.:|||:.:.:|:..:..|||.|.|.|:||||||
Zfish  3353 MVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLG 3417

  Fly  2994 LDVLGNPYGLVVGLKKGVEDLFYEPFQGAIQGPGEFAEGLVLGVKSLFGHTVGGAAGAVSKITGA 3058
            |||||||:||:.||.:|||..||||.|||:|||.|||||||:||:||.|||||||||.||:|||:
Zfish  3418 LDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGS 3482

  Fly  3059 MGKGLAALTFDEDYQKKRRQGIQNKPKNFHEGLARSSKGLVMGFVDGVTGVVTKPVTGARDNGVE 3123
            :||||||:|.|::||:|||:.:....|:|.|.||:..||.:.|.|.||||:|||||.||:..|..
Zfish  3483 VGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAA 3547

  Fly  3124 GFFKGLGKGAIGLVARPTAGVVDFASGSFEAVKRA----ADASEDVKRMRPPRFQHYDFVLRPYC 3184
            |||||:|||.:|:|||||.|:||.||.:|:.::|:    |:::|:|.::||.|..|.|.::|||.
Zfish  3548 GFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYD 3612

  Fly  3185 LMEATGNKIMKETDKGKFATTDNFIHCEEII---QKSEYLVVTNYRVMYVQRNEMFGVWTSLWSY 3246
            ...:.|..:.:   :.:....|..|..|..:   .:...:::||.|||.|:..::.|.:...|..
Zfish  3613 HHASEGYDLFQ---RSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWEC 3674

  Fly  3247 LWNEISSVAATARG 3260
            .:........|..|
Zfish  3675 QFESFQRPPCTEGG 3688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps13	NP_001260781.1	Chorein_N	4..113	CDD:315323	60/108 (56%)
		VPS13	140..370	CDD:318996	79/232 (34%)
		VPS13_mid_rpt	574..807	CDD:318998	77/232 (33%)
		SHR-BD	2349..2600	CDD:310922	90/257 (35%)
		VPS13	<2701..3232	CDD:330393	230/550 (42%)
		VPS13_C	2904..3074	CDD:318997	97/177 (55%)
vps13c	XP_021327607.1	Chorein_N	4..113	CDD:315323	60/108 (56%)
		VPS13	186..414	CDD:318996	78/231 (34%)
		VPS13_mid_rpt	614..838	CDD:318998	77/232 (33%)
		VPS13	<1245..>2613	CDD:330393	316/1494 (21%)
		SHR-BD	2766..3018	CDD:310922	90/257 (35%)
		VPS13	<3186..3635	CDD:330393	204/455 (45%)
		VPS13_C	3323..3498	CDD:318997	97/174 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583935
Domainoid	1	1.000	208	1.000	Domainoid score	I2809
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54975
OrthoDB	1	1.010	-	-		D4159at2759
OrthoFinder	1	1.000	-	-		FOG0001282
OrthoInspector	1	1.000	-	-		otm25658
orthoMCL	1	0.900	-	-		OOG6_101020
Panther	1	1.100	-	-	LDO	PTHR16166
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X990
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.860