Protein Alignment Vps13 and vps13b

DIOPT Version :9

• Sequence 1: NP_001260781.1
• Gene: Vps13 / 35693
• FlyBaseID: FBgn0033194
• Length: 3321
• Species: Drosophila melanogaster
• Sequence 2: XP_002934455.3
• Gene: vps13b / 100490880
• XenbaseID: XB-GENE-853604
• Length: 4027
• Species: Xenopus tropicalis
• Alignment Length: 4304
• Identity: 770/4304 - (17%)
• Similarity: 1371/4304 - (31%)
• Gaps: 1550/4304 - (36%)

  Fly     2 VFEAVVADVLNKVLGDYIENLDRNQLKIGIWGGDVVLQNLKIRENALD-ELDLPVQLIYGYLGKL 65
            :.|:.|..:|...:..||:||..:.|::.:|||||||..|:::.:.|: ||.||...:.|::.:|
 Frog     1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHEL 65

  Fly    66 VLKIPWKNLYSQPVIVNIEDLYVLVSPNNNVQYNAEK--EAKYEMDLKKAALDALEAARKKELEM 128
            .:.:||..|.|:.|::.|..:..::...:..|.:.|.  .:.......::|...::..:.::...
 Frog    66 RIHVPWTKLGSESVVITINTMECILKLKDGAQDDIESCGSSSTNRSTTESAKSPVKPRKVQQAAP 130

  Fly   129 DQPKADAGFAEKLTAQIVNNLQVQITNVHLRY-EDTTTTGSPFSFGISLHELELYTTDCDWEKCY 192
            ..|....|:.:.|..::|||:.:.:.|:.|:| ||...      ..:::...|.||.|..|::.:
 Frog   131 TDPDLPPGYVQSLIRRVVNNVNIVVNNLILKYVEDDIV------LSVNITCAECYTVDEFWDRAF 189

  Fly   193 MAQQASQVF--KIANLSCLSAYLNCGGQLYANNKSDLSQQFKTNIACK---ETKPNYNYVLGPIS 252
            |...|:::.  |:.|.|      :|...|...|.|...:.::..:..|   .|:.::.|    .|
 Frog   190 MDISATELVLRKVINFS------DCTVCLDKRNASGKIEFYQDPLLYKCSFRTRLHFTY----DS 244

  Fly   253 CNAKLKLNMNPELDDPPFEKPKIDLTLEMEKLNVGLTNTQ---FDNLMKLGDAM----------- 303
            .|:|:     |.:         |.:...::.|.:.||:.|   |..:|:||.|:
 Frog   245 LNSKM-----PSV---------IKIHTMVDSLKLSLTDQQLPMFIRIMQLGIALYYGEIGNTKDG 295

  Fly   304 ----------------NRQQL--GIPYRKYRPYNIPYKGHARDW----WHF--AITSILEEEVRK 344
                            ..::|  ||.|.....|.:......:.|    |.|  ||.|...||.
 Frog   296 EPDNPLNPTKDTIVSGGEEELGVGIQYPSQELYPMQDDDEQQGWVSWAWSFVPAIVSYGNEEE-- 358

  Fly   345 PRESWTWGHIKTHRERCNTYAQKYKEQCLSKKP---------SAVLTETCRLLETELDVFNLLLI 400
                   |.........||..|..|.. |||.|         .|.:|.....::||...::...:
 Frog   359 -------GEFGNAGLEDNTMLQGPKSH-LSKDPVISMGFYCTKATITLKLTEMQTESSYYSPQKV 415

  Fly   401 RQR---------VNIEIAKQRE-------------AV---------------------------- 415
            :.|         ..:|:....|             ||
 Frog   416 KSREVIRWEQEGTTVEVLMNGEPFFDCQVGFVGSRAVCLKGIMGIKDFEDISNRSDEEACFFTCG 480

  Fly   416 --------------------PE-------------------------QKSGWF-----------S 424
                                ||                         |:.|.|           |
 Frog   481 ENLSNKGNTYLTNSLFDYRSPENNGIRAEFILDSTLHKETYTEIAGMQRFGAFYMDYLYTMESTS 545

  Fly   425 GWG------WGGGAKKD----DQTTSQKLV-------------------------EKFEA----- 449
            |.|      :..|..::    .:.::::||                         .::||
 Frog   546 GKGPLNQQDFTSGKPEEQGFVQEMSTKRLVIGPIDLRLDSSSVHRIMKMVACSLDHEYEAYCSPP 610

  Fly   450 AMTSEEKEKM---------------------------------YRAIGY-------QENAKPTDL 474
            :.|.||.:.:                                 :..:|:       |::|.|..|
 Frog   611 SATVEENKSLPSPEDVASLEEYIPTRLSCVTILKCTITITMAEFNLLGHLIPVIMGQKHASPATL 675

  Fly   475 PESYEAIR-----------MNF-----------------------------------KLIALEVG 493
            ..|::.||           :||                                   |:...:.|
 Frog   676 NTSFQPIRPLPAIKILADKINFEHSVPMYAEQLVQTVSSLSQPSDNLLHHCYAHCYLKVFGFQAG 740

  Fly   494 L--------------------------------YKDERNSSAATKDFHELPSLVLLNFSMATALI 526
            |                                |...|......:...|||:|.:|.....|.|:
 Frog   741 LISIDSKGLCSSHVPVIPSFSTALYGKLLRLPQYWTSRAQVPVAEYIFELPNLTILATRAQTLLL 805

  Fly   527 TQRPAAEAI--SIIAGMREIKVTGLTRNDYTPLLVESKITDEFNLLEVFFET------NPLD--- 580
                  :||  |.|..         |:|..:.:|.|:       ||...|.|      |||.
 Frog   806 ------QAIYDSWIYS---------TKNSGSSVLNEA-------LLNEIFPTAGVKSKNPLPTLE 848

  Fly   581 --------KLCD-QRVKVVA---RPLQITYDAPTILA---LINAFQTPGDV----------TLSK 620
                    |.|. ..||.|:   ..::|...||..:.   ||...|.|.|.          ...|
 Frog   849 GSIQNIELKFCSTSLVKCVSGTVGSIKICAKAPGEVGKEKLIPLIQGPSDTRDLHRSMWLRESRK 913

  Fly   621 FEDAASTKISNFKERSATGMQYMIDKKAVL---------DVDILLMPNILVVPHK-----GVYDA 671
            .|......:..|..:....|.|.....|.|         :||.:|...:...|.|     .....
 Frog   914 PESLLGPDLIAFTIQVPEQMDYCHSSGAALLASIQGLAVNVDPVLYTWLTYHPQKRSSRQAQQPL 978

  Fly   672 GNVSLLV---------VSMGQVHLSSQPRRESNKLQHLFSAGEDKDEILKTVMENAYDRFTVAVD 727
            |:..|.|         ||:|...|:.||..:.:.    :::...|   .|||.|:.    .::|.
 Frog   979 GSAPLAVPLSRKKEDEVSIGSAPLAKQPSNQPSD----YASSPVK---TKTVTESR----PLSVP 1032

  Fly   728 DVQMLVVRAG-EPWQNALAEANSTEMHVLRPVSLKVTAALCVV----DNDPRLPNIKVDIDLPAI 787
            ...:|..|.| :..:..:.|...|..:.::.::|:|....|.|    |:.|. |:..|..|:|..
 Frog  1033 VKALLASREGSKSSEERMKEVIGTVWNAVKRLTLQVEIQTCCVFFPSDSLPS-PSTIVSSDIPGT 1096

  Fly   788 LVNVSEDR---------IFLAIKVATS--------------IPLPEQKEPASRLTQTNSRSSMSI 829
            :.:....:         .|..||:.::              :|.|..:|..: ...|.:..:.|:
 Frog  1097 VRSWYHGQACMPGTLVACFPQIKIMSAGHKYMEPIQEIPFIVPRPIVEEGVA-FPWTINLHNFSV 1160

  Fly   830 SNFINKE-----VKKIGPSA-----------SGSSASKDPLLDEIIQYTSLDVNFSLGEINF--- 875
            ...:..:     |:.:|.::           ||:.|....::...:....|::..|..::..
 Frog  1161 YTLLEHQLILNLVEPMGCTSTLAVTSHSLAGSGADAGHSFVVCLHVDLEPLEIKCSNPQVELLYQ 1225

  Fly   876 ----------------VLFQSSRKCETS-----------------PDVSIEFLTPDGDVLPSQLT 907
                            :|.|||..|::|                 ||.|.  .:|..||..:...
 Frog  1226 LTDTMSKVWEKIQRRGILHQSSIYCDSSTGPAPGSPVRSSVGTAPPDTST--CSPSADVGTTTEG 1288

  Fly   908 ENIQEPIEELP----PTPPQQILSIDIRRLEAHFVSKTYESVATVKLGDIN----------LRQY 958
            :::| ..|:.|    .|..|...:|.:.........:......||||..::          :.:.
 Frog  1289 DSLQ-AAEDSPFSDSVTLEQTTSNIGVSSGRVSLWMQWMLPKITVKLFSLDPGIKGGKICVVSEL 1352

  Fly   959 DCQDSDMDVLDVIYTP-----KQENSSNYLFT---------------VSCT-----------IAD 992
            :..::.:||.|| ||.     :..|..:|..:               :|||           ...
 Frog  1353 EDLNASVDVQDV-YTKVKCKIESFNIDHYRSSFSEDCWCLGQYGGVFLSCTDKLNRRTTLVRPVS 1416

  Fly   993 KSSP--EFSTKYNSTEQLVVANFEVLQIVLHQE----CLQRIMEVVNNFQRNLDLVLSSTRPRD- 1050
            |..|  .||..:.||...::.:       .||:    .|.....|..|.:..| ...|...||.
 Frog  1417 KQDPFSNFSGFFPSTTAKLLES-------SHQQHGFLSLTYTKAVTRNVRHKL-TSRSERSPRSF 1473

  Fly  1051 RMGSIGGGDGIKRTLNVILEDTE------------------EIMTTDQMKRRKKT----RRTHVV 1093
            :..|.|..|.....|:.||..::                  ::....:.|.::||    .|:|
 Frog  1474 QKFSEGPADASPHFLHEILISSQAFDIVVFFPLLNAVSRIFDVRCPPKQKEKRKTPRQPMRSH-- 1536

  Fly  1094 ETVKVRVIANLDQVGLVLTGRKRPIAEMNVKKFVSSLIIKSSYTE-------------------- 1138
                            .||.|..|:.      ::|:.:|:..:.:
 Frog  1537 ----------------ALTSRNLPLI------YISTSVIRVFFPKAEERQLASGGNQIINEDTLV 1579

  Fly  1139 VNIGLKDIQVLDLNPYTIHKNILSIVGKD----AFNCQIVIYNKEETQDYNS--DDMKITVDIGC 1197
            |.||...:.....||.:     .|::.||    |.|..|:       :|..|  :|.:..||:..
 Frog  1580 VKIGSVSMAPQADNPLS-----RSVLRKDIYQRALNLGIL-------RDPGSEVEDRQYQVDLQS 1632

  Fly  1198 MKIIFLNWFVAGVMNFLNNFTAAQATISQAGAAAAESARQKAMDAYETATRMKLNIRIKAPIIIV 1262
            :.|....|.........||           |...:|..|.....|.|  ..|..|||
 Frog  1633 INIGTAQWDQLKPEKESNN-----------GGLLSEGDRGTQNPALE--WNMASNIR-------- 1676

  Fly  1263 PIGSQDRNALLLDLGLLELTNNTVEVAVAE----------------------------------- 1292
              ..|:|.|||..:    ||:.||.:..|.
 Frog  1677 --RHQERRALLSPI----LTDCTVRITAAPAIIFTKMVSPENMQTEDILVCGHSLEVNVTTSLDF 1735

  Fly  1293 --------------EERLAVIDE--IKLQICDVKISKIVLLDGNESTVD---------------- 1325
                          :|.|...:|  :::::...:..|:..|||.  |||
 Frog  1736 FLSVAQVQLLQQLVQENLLGFEETGLEVEVSKQEHQKLDSLDGR--TVDTSSRYSGAQDSGIGSD 1798

  Fly  1326 -------EVDAEVGFLSKFNMMNPMSCTLSITRNLSYTWYRDVP-ELNLSG---RLKSIELTLFA 1379
                   :|:.:.| .|.:.::.| |...||.:||::     :| ::.::.   .|.|...|..|
 Frog  1799 SVKIRIVQVEQQSG-ASHYRIVRP-SKQSSIVKNLNF-----IPFDIFITASRISLMSYSCTALA 1856

  Fly  1380 ---------DDYALVMLVLNRNLNEGLEEFP--------PSEE--APQEAQVRP-----ER---- 1416
                     :......|.|..:..:|:.|.|        .:|:  ||.....||     ||
 Frog  1857 KQKSCPNDGEKIGKSSLNLTNSEADGVLEKPGDTCISTLTAEDLLAPHSVTTRPGLASLERLHAT 1921

  Fly  1417 -RNSRAGRLSRTV------------QVSPIREKI-----------HESIKFNFQFDGVVINLMEG 1457
             |:|....|..||            |::|....:           |...|........::..::.
 Frog  1922 TRSSARQALGITVVRQPGRRGTGDIQLNPFLHLVLSQPSLLISCHHRKQKLEISMFDALLKGVDP 1986

  Fly  1458 EGAGLARFGIYFLSVKGTKLDNGTLSTSVVLCNIQMDDMRSNSKSQIRQYLSRKDWVQPKLDTDE 1522
            |         |..|..|..|......|.:.|..:..:   .|.|:.|          .|...|.:
 Frog  1987 E---------YKCSDAGKTLPEVLDYTRIWLQTVAGE---RNCKTGI----------PPPFITLQ 2029

  Fly  1523 IIDACYNERNFMVDVTAIIKEDDTFAEVRVRGFDLIVCIDFLLKLTTFLT--------------- 1572
            |.|......:..:|::..:|.:.:|.:     ||.:..  |:.|:  ||:
 Frog  2030 IRDFLNGPADVNIDISRPLKVNLSFVK-----FDQVNL--FMKKI--FLSHHGGSSAEAHVIANQ 2085

  Fly  1573 -------LPPEENPRESVYIKPAPVSETA--RDT--------KHSIRSSAILAAQELVPVESS-- 1618
                   |.|.........:....:.:|:  .||        |.|.|::.::...|.:|...|
 Frog  2086 TATREEPLKPTSRKESGTAVSKESLKKTSLQEDTWSSVSCLQKVSFRTTQVVVNLETIPHAQSPC 2150

  Fly  1619 ----------------SHEVPNRKMNLILHIDEPDIILVENLEDLNTSCIIFNAQVHLNYRSIND 1667
                            .|:......:.:.|:|..|.|:..:|.|.|.:.|
 Frog  2151 ILTSFSDLQGSLSVQAGHKTAETVTSALFHLDINDFIIQTSLNDRNRNFI--------------- 2200

  Fly  1668 KQIVNGQIDALKMYMCAFLPERREMTRHYILHPCVISLQGSTPEEEGMHISLKLSDIIINVSPAT 1732
                 |.:..                        .::::.:..:..|              :|.:
 Frog  2201 -----GPVSG------------------------SVNVEANWCKHSG--------------NPGS 2222

  Fly  1733 IELLNKAMLSVSSGTMTKCAIAEESRNYSNLWHQ--HHFHSRTYWFT------------------ 1777
            ...:.|.::.|..|.| :....:|:.|...|.::  |.:..:....|
 Frog  2223 PHTIPKILVDVRGGVM-QVFWGQENLNCLTLLNELFHEYLKKDSRCTAMSNNPPLPSVSPAVGRP 2286

  Fly  1778 ---KVEQGVDALEAEQRSVSTDNEKQKTEKCVIEIPSITLVI-----ESGVGY----YTKPLISL 1830
               |.|...|.|.........|.:.|:       :|:...|:     |...|.    |.:|.:..
 Frog  2287 QTSKTEHSTDDLRTGFFQYIQDTDAQR-------VPNAYEVVFYNETEDNPGMMLWRYPEPRVLT 2344

  Fly  1831 DTRITAV-FNNWSRSLTAHGSL------TLNMNYYNQALAEWEPIIELNEVIGRNGV--REYTPW 1886
            ..|||.| ||.......:...|      ..::.|:::              :.|:.|  ||::..
 Frog  2345 LVRITPVPFNTTEDPDISTADLGDVLQVPCSLEYWDE--------------LQRSFVAFREFSLS 2395

  Fly  1887 ELK-FEMGMEKVQSELEDDAEQQAMHMNIHSAETLEITLSKTCLGLLSELAEAFSQAIDQNGLTK 1950
            |.| .|:.:..: |.:.|..|       :.:::...|.|:.:..|:..:.:|  |::..|:  :.
 Frog  2396 ESKACELQLPSI-SAVSDQKE-------LVTSDLWRIVLNSSANGIDDQSSE--SESGSQS--SS 2448

  Fly  1951 PDIVAPYVLENDTGFD-----------------VNLNLRKGIFTLHEVHRGGTPVGANSTLLMVA 1998
            ..:|.|..|...|..|                 |||.|.   ...|..|.|..|    ...|...
 Frog  2449 DQLVTPTALAACTRVDSCFTSWLVPSLGVSIQFVNLELH---LCHHLDHLGSVP----PKCLHPF 2506

  Fly  1999 QSEEVDPSVIKTCTIS-TGGRAYL-QTKDLSTLSEEDSEDYTLYVTIGDINKEIALPVSKSDTRF 2061
            .|::..|:.::..:|| ...:.|| |..|:|                  :.|||... ::::::|
 Frog  2507 VSDKTTPTELEYMSISFKEPQVYLRQWSDVS------------------VCKEIQFS-TEAESKF 2552

  Fly  2062 F---NLMRSTSHEPWGIISEVKQEYGTTK-------------VNIHGVVSVHNHFTTGLNIYRRN 2110
            .   ||...:..:|:.:..::.......:             ||. |..|||: ..|.:..:::|
 Frog  2553 LECRNLTMKSLVKPFHMQGQMAITDSALEKVLDFTVLVDPIFVNF-GQHSVHS-INTAILAWQQN 2615

  Fly  2111 PAPTAQ---------C---FEDIFVGRVRPGEVFHVPLHAIYAESKDLFFSMRGYRR------SV 2157
            ..|.|:         |   .|.:..|:|...|      :.:.|...:..:..|.::.      .:
 Frog  2616 QCPEAEELIYSHFVVCNDTQETLRFGQVDTDE------NIVLASLHNHQYCWRSHKSPQLLHICI 2674

  Fly  2158 QGISWASNPSDLNYSHQLHCDPTNTFEPLIMNARRSKSEVYFENTNKYTLLSAFYTIHLRPPLYL 2222
            :|  |    .:..:|.....|...||...|....|:.|.:.     |...|:.|..
 Frog  2675 EG--W----GNWRWSEPFSVDNAGTFVRTIQYKGRTASLII-----KIQQLNGFQK--------- 2719

  Fly  2223 RNSLPINIQVSVAG----CSVRKED----------GLDAQSSQR-FVDRGYRKEDFLDYGEKPVN 2272
                    ||::.|    ||...|.          |.|.|:..| .||....|:....|..:  |
 Frog  2720 --------QVTICGRQIICSYMSESIELKAVQHYIGQDGQAVVREHVDCLTAKQKLPSYVLE--N 2774

  Fly  2273 SGDVLHLPTVRLASKGKESKSFLVVRLVQYLEKDWSCATEIWDYTDDVITWTFSSYDSEMKVDMD 2337
            |    .|..:.:.:||.|:.|           :|...::|:.:::  :|....||.:|.:.|...
 Frog  2775 S----ELTELCVKAKGDEAWS-----------QDVCLSSELTEHS--MIIQVPSSNNSIIYVWCT 2822

  Fly  2338 LYVKTENRHGSLMLTLFSPFWM-------------------INKT----GMMLTYKSETTSVEVL 2379
            :............:.:|||.::                   :|:|    |..|....:....::.
 Frog  2823 IISLEPGSQVQQRMIMFSPLFIMRSHLPDSIIIHLEKRNLGLNETQLIPGKGLEKPLQNAEPDLT 2887

  Fly  2380 YH----------PPEYSGPILFTFRDKLFFDKKKASIRIDNGQWSEKIPLDVAGSVGEVICFANN 2434
            :|          |.|.:.||..:.       .|:.:.:..||..:.:|..:..|  ||      :
 Frog  2888 HHVTFQAREEDEPSECAVPISTSL-------IKQIATKAQNGYSANRILSEFYG--GE------S 2937

  Fly  2435 QKYPVGVHN--------HLTQ--------------NSLTKQITFIPFYIVCNKCHFDIELQEQSR 2477
            ...||..:|        ||.|              :..|..:..:|:.::.|:..:|:.|.|...
 Frog  2938 CPQPVWPYNKKDTDSGEHLAQWDSPMRVKLSLWKPHLKTLLVELLPWALLINQSRWDLWLFEGEN 3002

  Fly  2478 -----PADPWLHLEPNEMEPL-----WPRNDT--KNNLVVRVDGKITPAF---DFTEVICTLLKL 2527
                 ||...: :.||..|..     |...:|  |:..|..|....:|.:   |..||:    .|
 Frog  3003 IVLQIPAGQTI-IPPNFQEAFQIGIYWANTNTVHKSVAVRLVHDMTSPKWKDADNGEVV----TL 3062

  Fly  2528 EDSKYGGINVDV---------------QTTEGGVYITFTDYKPADAPGLLINHTGKQIVYH---- 2573
            ::..:...|:.:               ...:.|:.|...:.|..     :||:|..::.|.
 Frog  3063 DEEGFVDANIKLGAFPGHQKLCQFCISSMVQNGIQILQIEDKTT-----IINNTSLKVFYSPQIS 3122

  Fly  2574 --EKGTKNEHI---------LN-------AKSTIMYAWD---------DPTGPKML--------- 2602
              ::.::.|::         :|       ||...:..||         ..|.|..|
 Frog  3123 AIQQSSEEEYVPVPDSAVFSINPVGENQIAKPNPIPCWDVVSDVSQSSAETSPSPLQKYILLSLC 3187

  Fly  2603 --VFGTNKE--------ETDLKRDGIGEVIMQDGG-------------KVLWVSFL----DGLQR 2640
              |.|.|.:        ..:..|..:...:...||             :.|.:::|    |...|
 Frog  3188 PSVGGGNTQCWSLPAVIRQEYPRQSVAVPVGDCGGSGLCTKAIVLTYQEHLGLTYLTLTEDPCPR 3252

  Fly  2641 V---------LLFTEN-------ESIANRTESTASL----------------QSITQSIDLRI-- 2671
            :         ||..||       |....|..:..||                :.:..||.|::
 Frog  3253 IIIRNRCTVALLLKENIKEMPKFEVYCRRIPAECSLHHELYHQVSSFPDCKTKDLLPSIYLKVLS 3317

  Fly  2672 ------HGIGLSVINNETGLDILYLGVTSSGIIWESKKVTKNRFKELTINENA-----LLEIEYQ 2725
                  ....|..|||: |..:::|  |..|.::            :.|.::.     .|..|.:
 Frog  3318 HEDTATEWSDLIDINNQ-GTQVVFL--TGYGYVY------------VDIVQHCGTVIITLAPEGR 3367

  Fly  2726 KYLVHKSVNDVQTYKLDNKFPID------FDLMILKKTVERNLRRS----FY-----------PA 2769
            ...|..|:|..|:..:..||.|.      ||.:...||....||.:    |:           |.
 Frog  3368 AGPVLTSLNRSQSQSVMVKFFITQLSLGIFDDVTNAKTSSELLRLTLDNVFFSVTPVSSYLRQPC 3432

  Fly  2770 IWLSRK----SSPFQSQLHVKINRIQVDNQFLDPI---FPVVLAPIPPPKSV---------ASTT 2818
            :.|...    |:.|.| |.:....:|||||..:..   |||::.......|.         .||.
 Frog  3433 LELQADITCGSTLFYS-LEMYCGDLQVDNQLYNKSNFHFPVLVCQEERSDSARWAKSNGFQMSTK 3496

  Fly  2819 SLKPFIECSMVQRIMP----------NSTVRQFKYARILIQEFLFKVDLNFLTAIAEMFAKEVSD 2873
            .|:.|.|.|.|:..:.          |....:.|.:|:.:::       .|:..:..:|...:.|
 Frog  3497 ELEAFKESSFVKFFVSLSVEHEAYDLNELSFEMKPSRLYLED-------TFVYYVKTLFDTYLPD 3554

  Fly  2874 EAAAKQFRQDVESIELPLSAF-FE----EHSLEEQKSFYDNLHLGPLKIHVSFSMAGSDTKALPG 2933
            .             ::|.||. |.    .|.|.||...|....:.|:|:.   .:.......|..
 Frog  3555 S-------------KIPHSAVKFPGPKVNHLLPEQVRLYALALVNPVKLR---KLTVQPVNLLVS 3603

  Fly  2934 FLGSLVQGVGVTLTDVNDVVFRLAFFEREYQFFSQKQLINEITSHYTGQALKQLYVLVLGLDVLG 2998
            ...||...:....|.::     .:.|||...|.:.:||::.:..||...||.:...:|..|::||
 Frog  3604 IHASLKLYIASDHTPLS-----FSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLEILG 3663

  Fly  2999 NPYGLVVGLKKGVEDLFYEPFQGAIQGPGEFAEGLVLGVKSLFGHTVGGAAGAVSKITGAMGKGL 3063
            :|..||..:..|:.|.|..|::|..:|||.|..|:..|..|...|...|...:::.:..::.:.:
 Frog  3664 SPASLVRSIGNGIADFFRLPYEGLTRGPGAFVSGVSRGTSSFVKHISKGTLTSLTNLATSLARNM 3728

  Fly  3064 AALTFDEDYQKKRRQGIQNKPKNFHEGLARSSKGLVMGFVDGVTGVVTKPV---------TGARD 3119
            ..|:.||::..::.:..:..|.|..|||.:....|.:..:..:.|:|.:|:         .|:..
 Frog  3729 DRLSLDEEHYNRQEEWRRQLPDNLGEGLKQGLSRLGLSLLGAIAGIVDQPMQNFQRTSEAQGSAG 3793

  Fly  3120 NGVEGFFKGLGKGAIGLVARPTAGVVDFASGSFEAVKRAADASEDVK-RMRP---PRFQ----HY 3176
            :..:|...|:|||.:|:..:|..|..:..|.:...:...|..|:..| |:.|   |..|    |.
 Frog  3794 HKAKGVISGVGKGIVGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRLLPTDLPTHQLPNSHV 3858

  Fly  3177 DFVLRPYCLMEATG 3190
            .:|.:   ::::.|
 Frog  3859 KYVWK---MLQSLG 3869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps13	NP_001260781.1	Chorein_N	4..113	CDD:315323	31/111 (28%)
		VPS13	140..370	CDD:318996	57/273 (21%)
		VPS13_mid_rpt	574..807	CDD:318998	63/317 (20%)
		SHR-BD	2349..2600	CDD:310922	61/366 (17%)
		VPS13	<2701..3232	CDD:330393	123/564 (22%)
		VPS13_C	2904..3074	CDD:318997	41/169 (24%)
vps13b	XP_002934455.3	Chorein_N	6..>94	CDD:403729	28/87 (32%)
		SHR-BD	<2624..>2708	CDD:399561	16/95 (17%)
		MRS6	<3443..3862	CDD:227376	102/447 (23%)
		VPS13_C	<3615..3736	CDD:407143	34/125 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1642
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030