DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpe and F08F8.7

DIOPT Version :9

Sequence 1:	NP_001260780.1	Gene:	Rpe / 35692	FlyBaseID:	FBgn0050499	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_498620.1	Gene:	F08F8.7 / 176043	WormBaseID:	WBGene00017272	Length:	227	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	123/222 - (55%)
Similarity:	163/222 - (73%)	Gaps:	4/222 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPVQAKIGPSILNADLSNLAAESQKLLDNGADYLHLDVMDGTFVPNLTFGHPMVKSLRNKI-KTA 64
            |.::..:.||||||||::||:|.:|||..|||:||||||||.||||||||||:|:|||..: ...
Worm     1 MTLRPFVCPSILNADLASLASECKKLLAAGADWLHLDVMDGHFVPNLTFGHPVVESLRKSLGAEP 65

  Fly    65 FFETHMMVQNPEQWIEPMADAGVNLYTFHVEPVQDVVRVS---RRVQESGMKVGLAIKPGTEVQD 126
            ||:.|:||.||.||:||||.||.:.:|||.|.|...|.||   .::::|||||||::||||.|:.
Worm    66 FFDVHLMVSNPGQWVEPMAKAGASQFTFHYEAVDGDVAVSELIEKIRKSGMKVGLSVKPGTSVEH 130

  Fly   127 LEKYLSIADVVLVMTVEPGFGGQSFMADMMPKVKWLRENYPNLDIEVDGGVGPKTIHCCAEAGAN 191
            :.|:.:..|..|:||||||||||.||.:||.||:.:|..||||.|:|||||.|:.|...|:||||
Worm   131 ILKHANHLDNALIMTVEPGFGGQKFMENMMEKVRTIRSKYPNLTIQVDGGVTPENIEISAQAGAN 195

  Fly   192 MIVSGTAVVGASDQSQVIKELRDVVHS 218
            .|||||.::.|:|||..:..:|:.|.:
Worm   196 AIVSGTGIIKAADQSVAMTTIRNAVEA 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpe	NP_001260780.1	RPE	6..213	CDD:238244	120/210 (57%)
F08F8.7	NP_498620.1	PTZ00170	1..226	CDD:240303	123/222 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157331
Domainoid	1	1.000	233	1.000	Domainoid score	I1357
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12005
Inparanoid	1	1.050	245	1.000	Inparanoid score	I2050
Isobase	1	0.950	-	0	Normalized mean entropy	S332
OMA	1	1.010	-	-		QHG53606
OrthoDB	1	1.010	-	-		D1554029at2759
OrthoFinder	1	1.000	-	-		FOG0002457
OrthoInspector	1	1.000	-	-		oto17576
orthoMCL	1	0.900	-	-		OOG6_100819
Panther	1	1.100	-	-	LDO	PTHR11749
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1196
SonicParanoid	1	1.000	-	-		X1871
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890