Protein Alignment Corin and PRSS27

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 103/292 - (35%)
• Similarity: 141/292 - (48%)
• Gaps: 42/292 - (14%)

  Fly  1079 PMADLTCSNYECGRVKR----GRHKPSRRIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQ 1139
            |:..|.|  :...|.|.    ||.:...|::||.....|.||:..:|.....  .:|.|.||::|
Human     8 PLLLLLC--FGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGS--HFCGGSLIAEQ 68

  Fly  1140 WVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQL 1204
            |||||:||..|.|...|  :.:.||..:...........:|:.|..:|.| ...|...|:||.:|
Human    69 WVLTAAHCFRNTSETSL--YQVLLGARQLVQPGPHAMYARVRQVESNPLY-QGTASSADVALVEL 130

  Fly  1205 ATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKD----PKSTYEYIVNEVQVPIITRN 1265
            ...|.|..::||||||.||| ....|..|.|.|||...::|    |:     |:.::.||||...
Human   131 EAPVPFTNYILPVCLPDPSV-IFETGMNCWVTGWGSPSEEDLLPEPR-----ILQKLAVPIIDTP 189

  Fly  1266 QCDEWLDNL-------------TVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGI 1317
            :|     ||             |:...|:||||::|.||||:|||||||:| ..|:.  |...|:
Human   190 KC-----NLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVC-LVGQS--WLQAGV 246

  Fly  1318 VSWGIMCAHPRLPGVYANVVQYVPWIQEQIAK 1349
            :|||..||....||||..|..:..||...|.|
Human   247 ISWGEGCARQNRPGVYIRVTAHHNWIHRIIPK 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	93/258 (36%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	93/257 (36%)