Protein Alignment Corin and c1s.2

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001107921.2
• Gene: c1s.2 / 793504
• ZFINID: ZDB-GENE-030131-4645
• Length: 458
• Species: Danio rerio
• Alignment Length: 302
• Identity: 92/302 - (30%)
• Similarity: 134/302 - (44%)
• Gaps: 60/302 - (19%)

  Fly  1073 KKTEDYPMADLTCS-NYECGRVKRGRHKPSRRIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLI 1136
            |.|:.:|..:..|. |.|        ...:.|:.||..|..|..|:.......|..    :..||
Zfish   194 KLTKIFPKCEPVCGINME--------DLSAGRVFGGKPARSGEIPWQLLHKSSPRG----SATLI 246

  Fly  1137 SDQWVLTASHCV-GNYS--------VIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMA 1192
            ||.|.|||:..| ||.:        :::.:|         .|:.....:|     :|.||.|...
Zfish   247 SDYWALTAASLVDGNENRNMSWLGGIVNAQD---------TNAVFMETEK-----IIIHPNYKKV 297

  Fly  1193 ------IAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYE 1251
                  ...:|||||.:::..|....::.|||||..:...:..|.:.||.|:|         .|.
Zfish   298 DKDGRQSDFNNDIALIKMSAMVPLGPNIRPVCLPKKTDEAVKEGMMGTVSGFG---------VYG 353

  Fly  1252 YIVNEV----QVPIITRNQCDEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPG---EK 1309
            ..|:::    .|.:.:...|..  .:|.||:.|.|||.|..|.|:|.|||||||..|..|   |:
Zfish   354 RTVSKLLRYGHVHVYSLKSCVS--GDLPVSDNMFCAGDDVHGIDSCSGDSGGPLFFPMLGDGTEE 416

  Fly  1310 NRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQEQIAKHS 1351
            :|:.|.||||||.:||.....|.|..|..|:.||:|.:||:|
Zfish   417 HRYVVKGIVSWGPICAKTITKGYYTKVQNYLDWIEETMAKNS 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	81/263 (31%)
c1s.2	NP_001107921.2	CUB	25..133	CDD:238001
		Tryp_SPc	217..450	CDD:214473	80/261 (31%)