Protein Alignment Corin and st14b

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001429317.1
• Gene: st14b / 777629
• ZFINID: ZDB-GENE-061103-613
• Length: 864
• Species: Danio rerio
• Alignment Length: 846
• Identity: 207/846 - (24%)
• Similarity: 326/846 - (38%)
• Gaps: 259/846 - (30%)

  Fly   603 SKINFRQDSTISSDSFSQT--SSPGYNPKLMEAPLLPSL----------------SAKRLCSAPA 649
            ||::..:::..|.|....|  |..|:: ::.::.::..:                |:||...|.|
Zfish   171 SKVSALEEAIASMDDTENTRKSRRGFS-RMTDSLIIDGITSGAVDARLADRNLKRSSKRSNHAHA 234

  Fly   650 ---PIVCRQGVQHEPIEELEPPQTISPLHKAAGQPSSLQTIVRFQNGAPHTMSLQHQIINRRKSS 711
               .|:...|.         |..:.||         :|.|..:.:....|.:.|:..:::..|..
Zfish   235 NQTDIIRSPGF---------PDNSYSP---------NLYTEWQIRADPEHRVRLEFDVLDLEKDC 281

  Fly   712 NPYITNGRLKFRLFQILINAFALLAIAGGLAAYFNAYPTIKFV----------NKTII-----NT 761
            :                 |.|        :..|.:..|:.|.|          |:.:|     |.
Zfish   282 H-----------------NDF--------IKVYDSLAPSEKLVITEKCGYRLPNEKLIFISSGNV 321

  Fly   762 IHVEDTTSFGKNPAPG-----TCLPIIVRFCQGPQIPYNYT------VFPNYIGHF-GQLETQTD 814
            :.|...|:..|| .||     :.:|..::.|.|     ..|      ..|.|..|: .|:|...:
Zfish   322 MLVTMVTNEEKN-YPGFRAIYSQIPAKIQDCGG-----RLTGLRGAFTSPGYPSHYPPQIECVWN 380

  Fly   815 LDSYEALVDVRCYELVSLFLCTLFVPKCGQSGATVPPCKTLCTETMRRCGFFFDVFGLSLPE--Y 877
            ::                                |||.|.:..:        ||.|.:..||  .
Zfish   381 IE--------------------------------VPPGKHIKVK--------FDKFSIHNPEQNI 405

  Fly   878 LNC--------------------------KLFKDFPSSEDCV--GLDEVREVMRAATHPKCDG-F 913
            :||                          :|...|.|....|  |.....|... .|:| |.| |
Zfish   406 INCPTDYLELNYRICGEKPPKTVYTVKSNQLTVKFNSDRSYVSEGFSAEFEAFE-PTNP-CPGRF 468

  Fly   914 QCDQNRCLPQEYVCDGHLDCMDQADEAKCERCGPDEIYCGDSQCIGTKHICDGIIDCPYGQDERN 978
            :||.:.|:..:..|||:.||.|.:||..| .|...:|.|.:..|..:...|||:.||....||.|
Zfish   469 ECDNDLCISSDQHCDGYNDCGDMSDERGC-MCNETQIQCKNGFCKPSFWGCDGVNDCGDNTDEEN 532

  Fly   979 CLRLSERNGDVGTGVLEVYRIGQRQWMPACVKNWDRAVSPSAVCSILGYS--------------- 1028
            |       |:..|            |...|...  |.:|....|:  ||:
Zfish   533 C-------GNCKT------------WEFRCRSG--RCISAQKQCN--GYNDCGDGSDESRCAKSI 574

  Fly  1029 AVNATSVLTQLTHRPLLATVNVSTDIWKMYAKRKSTLMQEFANCKKTEDYPMADLTCSNYECGRV 1093
            ||:.:....:..::..::.:|...|     .:.......:.|.||                ||:
Zfish   575 AVHCSDSTYKCKNKQCISKLNPMCD-----GETDCVDGSDEAECK----------------CGK- 617

  Fly  1094 KRGRHKP--SRRIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASHCVGN-----Y 1151
                 ||  |.||:||..:..|.||:..: |....:...|...:||:.|::||:|||.:     |
Zfish   618 -----KPHKSSRIVGGKDSDEGEWPWQVS-LHMKTQGHVCGASVISNSWLVTAAHCVQDNDQFRY 676

  Fly  1152 SVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLP 1216
            |..|  .|.:.||:..:...:.|.|: .|..:||||||:.: ::||||||.:|.:.|..::::.|
Zfish   677 SQAD--QWEVYLGLHNQGETSKSTQR-SVLRIIPHPQYDHS-SYDNDIALMELDSPVTLNQNIWP 737

  Fly  1217 VCLPPPSVRNLHP-GTLCTVIGWGK-REDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTVSEG 1279
            :|||.|:  :..| |....:.|||| ||..|...:   ::.:.:|.||....|.:.:|: .::..
Zfish   738 ICLPDPT--HYFPAGKSVWITGWGKLREGSDAVPS---VLQKAEVRIINSTVCSKLMDD-GITPH 796

  Fly  1280 MVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQ 1344
            |:|||...||.|||||||||| :....| ..|.|:.|:||||..|.....||||..|..|..||:
Zfish   797 MICAGVLSGGVDACQGDSGGP-MSSIEG-NGRMFLAGVVSWGDGCGRRNRPGVYTRVTDYRSWIR 859

  Fly  1345 E 1345
            |
Zfish   860 E 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	24/152 (16%)
		LDLa	911..942	CDD:238060	13/31 (42%)
		LDLa	945..979	CDD:238060	11/33 (33%)
		SR	980..>1034	CDD:214555	11/68 (16%)
		Tryp_SPc	1104..1346	CDD:238113	92/249 (37%)
st14b	NP_001429317.1	None