DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Corin and Tmprss12

DIOPT Version :9

Sequence 1:NP_610297.2 Gene:Corin / 35691 FlyBaseID:FBgn0033192 Length:1397 Species:Drosophila melanogaster
Sequence 2:NP_898932.2 Gene:Tmprss12 / 75002 MGIID:1922252 Length:336 Species:Mus musculus


Alignment Length:346 Identity:102/346 - (29%)
Similarity:163/346 - (47%) Gaps:48/346 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly  1011 NWDRAVSPSAVC--SILGYSAVNATSVLTQLTHRPLLATVNVSTDIWKMYAKRKSTLMQEFANCK 1073
            :|  |:|.:.:|  ....||.:::.|:                        :..|.|.|......
Mouse     3 SW--ALSAALLCLGGAFAYSELHSLSL------------------------REGSALGQATVPGP 41

  Fly  1074 KTEDYPMADLTCSNYECGRVK-RGRHKPSRRIIGGTQASPGNWPFLAA--ILGGPEKIFYCAGVL 1135
            ..|:.|:..      :||... ||..:.| |||||:||..|.||:..:  :..|...:..|.|.|
Mouse    42 PEEEQPVTK------DCGIAPLRGAVEGS-RIIGGSQADTGAWPWQVSLQVQDGDILMHVCGGAL 99

  Fly  1136 ISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIA 1200
            :.|:|||||:||  .....|...|...:|........|..:.:::..:|..|.:.|. ...||||
Mouse   100 VRDRWVLTAAHC--TKEARDPLKWRAVMGTNDLTRSPYHSRNIRITDIIIPPDFIME-TFVNDIA 161

  Fly  1201 LFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRN 1265
            ||:|...|.:::::.|:|||....:.|...|.|.:.|||:..::...:|   |:.|.:|..|:|.
Mouse   162 LFRLKRAVRYNDYIQPICLPFGVFQKLDQNTACFISGWGRTREEGNGTT---ILQEAKVHFISRE 223

  Fly  1266 QC--DEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPR 1328
            .|  |:....: :.....|||.::|..|:|:|||||||:|..| |.:|:||.||.|:|..|....
Mouse   224 VCSSDQGYSGM-IPNTSFCAGHENGTFDSCRGDSGGPLMCYLP-EHSRYFVMGITSYGHGCGRRH 286

  Fly  1329 LPGVYANVVQYVPWIQEQIAK 1349
            .||||:|...:..|:...:::
Mouse   287 FPGVYSNPSFFQEWMTHYLSQ 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CorinNP_610297.2 CRD_FZ 778..894 CDD:143549
LDLa 911..942 CDD:238060
LDLa 945..979 CDD:238060
SR 980..>1034 CDD:214555 6/24 (25%)
SRCR 992..1086 CDD:278931 12/76 (16%)
Tryp_SPc 1103..1343 CDD:214473 84/243 (35%)
Tryp_SPc 1104..1346 CDD:238113 84/245 (34%)
Tmprss12NP_898932.2 Tryp_SPc 65..300 CDD:214473 84/242 (35%)
Tryp_SPc 66..300 CDD:238113 83/241 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24253
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.