DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Corin and XB5723326

DIOPT Version :9

Sequence 1:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	NP_001037931.1	Gene:	XB5723326 / 733551	XenbaseID:	XB-GENE-5723327	Length:	349	Species:	Xenopus tropicalis

Alignment Length:	307	Identity:	89/307 - (28%)
Similarity:	147/307 - (47%)	Gaps:	48/307 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1108 TQASP--GNWPFLAAILGGPEKI-----FYCAGVLISDQWVLTASHCVGNYSVIDLEDW------ 1159
            |:.:|  |.||::.:|   .:|:     ..|||.:::::|::||:||        .:||
Frog    18 TELNPVEGKWPWIVSI---QKKVELGYKHICAGTILNNEWIITAAHC--------FKDWKEGDPT 71

  Fly  1160 ---TIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPP 1221
               .:.||....:......|...||.:|.|.||: .|...|||||.||..:|.|.:|:...|.|.
Frog    72 TPLRVLLGTFYLSEIGLRTQSRGVKQLIKHDQYD-PITESNDIALIQLDKQVEFSDHIQQACFPK 135

  Fly  1222 PSVRNLHPGTLCTVIGWGKR-EDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTVSEGMVCAGF 1285
            .|. :|.....|::.|||.: :..|..|.:   :.|.||..|....|::|...: :.|..:|||.
Frog   136 ESA-DLKDLIDCSIAGWGAQGKHLDEPSQF---LQEAQVERIDTKHCNKWYQGI-LGENHLCAGH 195

  Fly  1286 DDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQEQIAKH 1350
            ..|.:..|.||.|.||:| ...:.|.:.|.||::||..|...|.||||:.:..::.||.|:
Frog   196 RKGPEKTCNGDRGSPLMC-RTKKNNVYSVIGILNWGSGCGQTRSPGVYSPIQSHIKWIVEK---- 255

  Fly  1351 SRPIKEDRVNKYDLHPGGPDILSKIATDPMREGAPHHYTHSRTSSKN 1397
               :|.:.| |..:.  |..::.|:....::   |.|...:|.:::|
Frog   256 ---VKNEAV-KATIQ--GKRLVPKLLFPLVK---PDHMNPNRNTAQN 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931
		Tryp_SPc	1103..1343	CDD:214473	77/251 (31%)
		Tryp_SPc	1104..1346	CDD:238113	79/254 (31%)
XB5723326	NP_001037931.1	Tryp_SPc	25..252	CDD:214473	75/244 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010