Protein Alignment Corin and PRSS56

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 110/304 - (36%)
• Similarity: 151/304 - (49%)
• Gaps: 51/304 - (16%)

  Fly  1096 GRHKPSR--------RIIGGTQASPGNWPFLAAI-LGGPEKIFYCAGVLISDQWVLTASHC-VGN 1150
            |..:||.        ||:||:.|.||.||:|..: |||..   .|.|||::..|||||:|| ||.
Human    89 GERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQP---LCGGVLVAASWVLTAAHCFVGA 150

  Fly  1151 YSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLL 1215
            .:.:   .||:.|....|..   ..::|.|..::|||:::....| ||:||.||.|.|:......
Human   151 PNEL---LWTVTLAEGSRGE---QAEEVPVNRILPHPKFDPRTFH-NDLALVQLWTPVSPGGSAR 208

  Fly  1216 PVCLP-----PPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLT 1275
            |||||     ||:      ||.|.:.|||...:..|::.   .|.|.:||:::.:.|...|....
Human   209 PVCLPQEPQEPPA------GTACAIAGWGALFEDGPEAE---AVREARVPLLSTDTCRRALGPGL 264

  Fly  1276 VSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYV 1340
            ....|:|||:..||.|:|||||||||.|..||.:.|..:.|:.|||..|..|..||||..|..:.
Human   265 RPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFK 329

  Fly  1341 PWIQEQI--AKHSRPIKEDRVNKYDLHPGGPDILSKIATDPMRE 1382
            .|:|||:  |..||.               |.....:|.||.:|
Human   330 DWLQEQMSAASSSRE---------------PSCRELLAWDPPQE 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	96/248 (39%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	96/248 (39%)
		PksD	<178..600	CDD:442550	75/206 (36%)