| Sequence 1: | NP_610297.2 | Gene: | Corin / 35691 | FlyBaseID: | FBgn0033192 | Length: | 1397 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_065256.1 | Gene: | Fzd2 / 57265 | MGIID: | 1888513 | Length: | 570 | Species: | Mus musculus |
| Alignment Length: | 209 | Identity: | 56/209 - (26%) |
|---|---|---|---|
| Similarity: | 81/209 - (38%) | Gaps: | 45/209 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 774 PAPGTCLPIIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLCTLF 838
Fly 839 VPKCGQSGATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSEDCVGLDEVRE--- 900
Fly 901 ---------------------------VMRAAT--HPKCDGFQCDQNRCLPQ--EYVCDGHLDCM 934
Fly 935 DQADEAKCERCGPD 948 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Corin | NP_610297.2 | CRD_FZ | 778..894 | CDD:143549 | 35/115 (30%) |
| LDLa | 911..942 | CDD:238060 | 8/32 (25%) | ||
| LDLa | 945..979 | CDD:238060 | 2/4 (50%) | ||
| SR | 980..>1034 | CDD:214555 | |||
| Tryp_SPc | 1104..1346 | CDD:238113 | |||
| Fzd2 | NP_065256.1 | CRD_FZ2 | 40..166 | CDD:143573 | 38/127 (30%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 166..194 | 0/27 (0%) | |||
| 7tmF_FZD2 | 239..568 | CDD:320373 | |||
| TM helix 1 | 248..273 | CDD:320373 | |||
| TM helix 2 | 282..303 | CDD:320373 | |||
| TM helix 3 | 333..359 | CDD:320373 | |||
| TM helix 4 | 376..392 | CDD:320373 | |||
| TM helix 5 | 414..443 | CDD:320373 | |||
| TM helix 6 | 463..490 | CDD:320373 | |||
| TM helix 7 | 519..544 | CDD:320373 | |||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 548..553 | ||||
| PDZ-binding | 568..570 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||