Protein Alignment Corin and Prss21

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_065233.2
• Gene: Prss21 / 57256
• MGIID: 1916698
• Length: 324
• Species: Mus musculus
• Alignment Length: 286
• Identity: 102/286 - (35%)
• Similarity: 144/286 - (50%)
• Gaps: 50/286 - (17%)

  Fly  1090 CGRVKRGRHKPSRRIIGGTQASPGNWPFLAAILGGPEKIF---YCAGVLISDQWVLTASHCVGNY 1151
            ||.    |..|| ||:||..|..|.||:..::     :::   .|...|::.:|||||:||....
Mouse    46 CGH----RTIPS-RIVGGDDAELGRWPWQGSL-----RVWGNHLCGATLLNRRWVLTAAHCFQKD 100

  Fly  1152 SVIDLEDWTIQLG-VTRRNSF----TYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFH 1211
            :  |..|||:|.| :|.|.|.    .|| .:.:::.:...|:|:.  .:.|||||.:|::.|.::
Mouse   101 N--DPFDWTVQFGELTSRPSLWNLQAYS-NRYQIEDIFLSPKYSE--QYPNDIALLKLSSPVTYN 160

  Fly  1212 EHLLPVCLPPPSVRNLHPGTLCTVIGWGK-REDKDPKSTYEYIVNEVQVPIITRNQCDE------ 1269
            ..:.|:|| ..|.......|.|.|.|||. .||:...|  ...:.||||.||..:.|:.
Mouse   161 NFIQPICL-LNSTYKFENRTDCWVTGWGAIGEDESLPS--PNTLQEVQVAIINNSMCNHMYKKPD 222

  Fly  1270 -----WLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRL 1329
                 |.|       |||||..:||||||.|||||||.|   .:...|:..|:|||||.|..|..
Mouse   223 FRTNIWGD-------MVCAGTPEGGKDACFGDSGGPLAC---DQDTVWYQVGVVSWGIGCGRPNR 277

  Fly  1330 PGVYANVVQYVPWIQEQIAKHS--RP 1353
            ||||.|:..:..|||..:.::.  ||
Mouse   278 PGVYTNISHHYNWIQSTMIRNGLLRP 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	94/261 (36%)
Prss21	NP_065233.2	Tryp_SPc	55..294	CDD:238113	94/261 (36%)