Protein Alignment Corin and PRSS8

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 101/265 - (38%)
• Similarity: 141/265 - (53%)
• Gaps: 33/265 - (12%)

  Fly  1100 PSRRIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLG 1164
            |..||.||:.|..|.||:..:|.  .|.:..|.|.|:|:||||:|:||..  |....|.:.::||
Human    41 PQARITGGSSAVAGQWPWQVSIT--YEGVHVCGGSLVSEQWVLSAAHCFP--SEHHKEAYEVKLG 101

  Fly  1165 VTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPPPSV---RN 1226
            ..:.:|::...:...:|.:||||.| :......||||.||:..:.|..::.|:|||..:.   ..
Human   102 AHQLDSYSEDAKVSTLKDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNG 165

  Fly  1227 LHPGTLCTVIGWGKREDK----DPKSTYEYIVNEVQVPIITRNQCDEWLDNLT--------VSEG 1279
            ||    |||.|||.....    .||.     :.:::||:|:|..|: .|.|:.        |.|.
Human   166 LH----CTVTGWGHVAPSVSLLTPKP-----LQQLEVPLISRETCN-CLYNIDAKPEEPHFVQED 220

  Fly  1280 MVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQ 1344
            |||||:.:||||||||||||||.||..|   .|::.||||||..|.....||||.....|..|||
Human   221 MVCAGYVEGGKDACQGDSGGPLSCPVEG---LWYLTGIVSWGDACGARNRPGVYTLASSYASWIQ 282

  Fly  1345 EQIAK 1349
            .::.:
Human   283 SKVTE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	99/256 (39%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	99/256 (39%)