Protein Alignment Corin and prss8

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001016980.1
• Gene: prss8 / 549734
• XenbaseID: XB-GENE-5758112
• Length: 329
• Species: Xenopus tropicalis
• Alignment Length: 279
• Identity: 92/279 - (32%)
• Similarity: 136/279 - (48%)
• Gaps: 40/279 - (14%)

  Fly  1083 LTCSNYECGRVKRGRHKPSRRIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASHC 1147
            |..|::|.||.:.|   ...||:||..||.|.:|:.|::......:  |...|||..:::||:||
 Frog    12 LAVSHFELGRSQEG---VQSRIVGGHDASEGMFPWQASLRYDGNHV--CGAALISANFIVTAAHC 71

  Fly  1148 V-GNYSVIDLEDW--TIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHD---NDIALFQLAT 1206
            . .::|::....:  .:||||...||     |.:|:|.|..:|.|    :||   .|:|:..|.:
 Frog    72 FPSDHSLVGYSVYLGVLQLGVPSSNS-----QLLKLKQVTIYPSY----SHDTSSGDLAVAALDS 127

  Fly  1207 RVAFHEHLLPVCLPPPSVRNLHP-GTLCTVIGWGKRED--KDPKSTYEYIVNEVQVPIITRNQCD 1268
            ...|...:.|:.||..:|:  .| |..|.|.|||..:.  ..|.:....:.|   |.:|.|..|:
 Frog   128 PATFSHVVQPISLPAANVQ--FPIGMTCQVTGWGNIQQGVNLPGAKNLQVGN---VKLIGRQTCN 187

  Fly  1269 EWLDNL--------TVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCA 1325
             .|.|:        ::...|:|||...|..|||||||||||.|...|:.   ::..:||||..|.
 Frog   188 -CLYNIKPSADSMGSIQPDMICAGSAAGSVDACQGDSGGPLTCTVNGKA---YLAAVVSWGDECG 248

  Fly  1326 HPRLPGVYANVVQYVPWIQ 1344
            ....||||..:..|..|||
 Frog   249 AQNKPGVYILISAYASWIQ 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	85/258 (33%)
prss8	NP_001016980.1	Tryp_SPc	30..269	CDD:238113	85/258 (33%)