Protein Alignment Corin and Sfrp5

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_061250.2
• Gene: Sfrp5 / 54612
• MGIID: 1860298
• Length: 314
• Species: Mus musculus
• Alignment Length: 272
• Identity: 67/272 - (24%)
• Similarity: 100/272 - (36%)
• Gaps: 57/272 - (20%)

  Fly   769 SFGKNPAPGTCL--PIIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVS 831
            |:.|   |..||  |..:..|.  .:.|.....||.:.|....|.:....|:..|:..||:....
Mouse    43 SYSK---PPQCLDIPADLPLCH--TVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQ 102

  Fly   832 LFLCTLFVPKCGQSGATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSED-CVGL 895
            :|||:||.|.|  ....:.||::||......|....:.:|...||.|:|   ..||...| |:.
Mouse   103 VFLCSLFAPVC--LDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHC---HKFPLDNDLCIA- 161

  Fly   896 DEVREVMRAATHPKCDGF--QCDQNRCLPQEYVCDGHLDCMDQADEAKCERCGPDEIYCGDSQCI 958
              |:.....||.|.....  ||:      .|:..||.::.|..:|.....|....:|..||.:.|
Mouse   162 --VQFGHLPATAPPVTKICAQCE------MEHSADGLMEQMCSSDFVVKMRIKEIKIDNGDRKLI 218

  Fly   959 GTK---------------------HICDGIIDCPYGQDERNCLRLSERNGDVGTGVLEVYRIGQR 1002
            |.:                     |:.:| ..||       |.:|....|    ..|.:.|..:.
Mouse   219 GAQKKKKLLKAGPLKRKDTKKLVLHMKNG-ASCP-------CPQLDNLTG----SFLVMGRKVEG 271

  Fly  1003 QWMPACVKNWDR 1014
            |.:...|..||:
Mouse   272 QLLLTAVYRWDK 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	34/118 (29%)
		LDLa	911..942	CDD:238060	7/32 (22%)
		LDLa	945..979	CDD:238060	9/54 (17%)
		SR	980..>1034	CDD:214555	8/35 (23%)
		Tryp_SPc	1104..1346	CDD:238113
Sfrp5	NP_061250.2	CRD_SFRP5	44..170	CDD:143553	37/138 (27%)
		NTR_Sfrp1_like	175..300	CDD:239635	26/127 (20%)