Protein Alignment Corin and CELA2B

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_056933.3
• Gene: CELA2B / 51032
• HGNCID: 29995
• Length: 269
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 82/261 - (31%)
• Similarity: 125/261 - (47%)
• Gaps: 32/261 - (12%)

  Fly  1103 RIIGGTQASPGNWPFLAAILGGPEKIFY--CAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGV 1165
            |::||.:|.|.:||:..::.......:|  |.|.||::.|||||:||:.:..:     :.:.||
Human    28 RMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGI-----YRVMLG- 86

  Fly  1166 TRRNSF-TYSGQ-KVKVKAVIPHPQYNM-AIAHDNDIALFQLATRVAFHEHLLPVCLPPPS--VR 1225
             :.|.: ..||. .|.|..::.|..:|. .::..|||||.:||..|:..:.:...||||..  :.
Human    87 -QHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLPPAGTILP 150

  Fly  1226 NLHPGTLCTVIGWGKREDKD--PKSTYEYIVNEVQVPIITRNQCDE--WLDNLTVSEGMVCAGFD 1286
            |.:|   |.|.|||:.:...  |..     :.:.|:.::....|..  |..: ||...|:||| .
Human   151 NNYP---CYVTGWGRLQTNGALPDD-----LKQGQLLVVDYATCSSSGWWGS-TVKTNMICAG-G 205

  Fly  1287 DGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWG--IMCAHPRLPGVYANVVQYVPWIQEQIAK 1349
            ||....|.|||||||.|  .....||.|.||.|..  :.|.:...|.::..|..|..||...||.
Human   206 DGVICTCNGDSGGPLNC--QASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVIAN 268

  Fly  1350 H 1350
            :
Human   269 N 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	79/254 (31%)
CELA2B	NP_056933.3	Tryp_SPc	31..265	CDD:238113	79/252 (31%)