Protein Alignment Corin and Prss44

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001388157.1
• Gene: Prss44 / 501060
• RGDID: 1560940
• Length: 373
• Species: Rattus norvegicus
• Alignment Length: 268
• Identity: 94/268 - (35%)
• Similarity: 143/268 - (53%)
• Gaps: 30/268 - (11%)

  Fly  1090 CGRVKRGRHKPSRRIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASHCVGNYSVI 1154
            ||      |: :.||:||..|....||:..::....:.|  |.|.|||..||:||:|||..:.
  Rat   106 CG------HR-TARIVGGKPAPIRKWPWQVSLQVHKQHI--CGGSLISKWWVMTAAHCVYGHL-- 159

  Fly  1155 DLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCL 1219
               |:.:.:|  ..:.::....|:.|:.:|.|..|::.....:||||..||..|.:..::.|||:
  Rat   160 ---DYVVSMG--EADLWSSMSVKIPVQDIIVHQDYSVMRTIVHDIALVLLAFPVNYSVNIQPVCI 219

  Fly  1220 PPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLT------VSE 1278
            |..|.. :.|||||.|.||||..::...|.   ::.||.:.||...:|::.|.::|      |.|
  Rat   220 PEKSFL-VQPGTLCWVTGWGKTIERGRSSR---VLREVDLSIIRHERCNQILKDITGRIFTLVQE 280

  Fly  1279 GMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWI 1343
            |.|| |::..|.||||||||||::|.:   ...|...||||||:.|.....||:|..|..|..||
  Rat   281 GGVC-GYNKKGGDACQGDSGGPMVCEF---NKTWVQVGIVSWGLGCGRIGYPGIYTEVSYYRDWI 341

  Fly  1344 QEQIAKHS 1351
            .:::::.|
  Rat   342 IKELSRAS 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	89/247 (36%)
Prss44	NP_001388157.1	Tryp_SPc	113..341	CDD:238113	87/244 (36%)