Protein Alignment Corin and Tmprss11c

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001399454.1
• Gene: Tmprss11c / 408213
• RGDID: 1302967
• Length: 431
• Species: Rattus norvegicus
• Alignment Length: 302
• Identity: 104/302 - (34%)
• Similarity: 156/302 - (51%)
• Gaps: 38/302 - (12%)

  Fly  1057 MYAKRKS--TLMQEFANCKKTE-DYPMA-DL--TCSNYECGR--VKRGRHKPSRRIIGGTQASPG 1113
            :|.|.||  .|:.:.::.|.:: ..|:| ||  ||    |||  :..|.||    :.||..|..|
  Rat   153 LYQKLKSQTRLLIDSSSFKFSDIAMPIAEDLLNTC----CGRRTITPGGHK----VAGGQDAEEG 209

  Fly  1114 NWPFLAAILGGPEKIFYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKV 1178
            .||:.|::  ....:..|...|||:.|::||:||....:  :.:||.:..|      |..|..:.
  Rat   210 EWPWQASL--QQNNVHRCGATLISNSWLITAAHCFVRSA--NPKDWKVSFG------FLLSKPQA 264

  Fly  1179 K--VKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGK- 1240
            :  ||:::.|..|:.. ||:||||:.:|::.|.:..::...|| |.:.:...|.:...|.|||.
  Rat   265 QRAVKSIVIHENYSYP-AHNNDIAVVRLSSPVLYENNIRRACL-PEATQKFPPNSDVVVTGWGTL 327

  Fly  1241 REDKDPKSTYEYIVNEVQVPIITRNQCDEW-LDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCP 1304
            :.|.|..:    |:.:.:|.||....|:.. .....::.||:||||.:|..|||||||||||:.
  Rat   328 KSDGDSPN----ILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGGPLVS- 387

  Fly  1305 YPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQEQ 1346
             ...|..||:.||||||..||.|..||||..|..|..||..:
  Rat   388 -EDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWISSK 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	86/245 (35%)
Tmprss11c	NP_001399454.1	SEA	62..161	CDD:460188	4/7 (57%)
		Tryp_SPc	200..428	CDD:238113	86/245 (35%)