Protein Alignment Corin and CG10663

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001097592.1
• Gene: CG10663 / 39421
• FlyBaseID: FBgn0036287
• Length: 748
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 171/688 - (24%)
• Similarity: 255/688 - (37%)
• Gaps: 174/688 - (25%)

  Fly   749 PTIKFVNKTIINTIHVEDTTSFGKNPAPGTCLP----IIVRFC----QGPQIPYNYTVF---PNY 802
            |.||:....|::..|:.:.......|.|....|    ||:...    .||.:.|.||.:   |||
  Fly   129 PAIKWQPPLILDDSHIRERIQPLPQPQPQPPPPPPPSIIINAAAAASSGPTVDYRYTEYKPPPNY 193

  Fly   803 IGHFGQLETQTDLDSYEAL---VDVRCYELVSLFLCTLFVPKCGQSGATVPPCKTLCTETMRRCG 864
            ...:..........:|.|.   .....|.          .|....:....||  |...|.:|.
  Fly   194 ASLYPSTHPPIYTPTYPAAHPPTQPPTYP----------PPTHPPTPPPTPP--TNPDEVVRH-- 244

  Fly   865 FFFDVFGLSLPEYLNCKLFKDF--------PSSEDCVGLDEVRE--VMRAATHPKCDGFQCDQNR 919
                     ||:|....:|.:.        ...||.:..||..:  |::...|.:....:...:|
  Fly   245 ---------LPKYPGKDIFSEEDVEDELEPEPDEDLISSDEQGDFFVLKHHRHRRRQNHRRPSHR 300

  Fly   920 CLPQEYVCDGHLDCMDQADEAKCERCGPDEIYCGDSQCIGTKHICDGIIDCPYGQDERNCLRLSE 984
            ..|:|          :..|::       |.:..|:.:.:..:|:         |:|       |.
  Fly   301 KPPKE----------EDYDDS-------DFVDFGERKSLRHRHL---------GED-------SS 332

  Fly   985 RNGDV---------GTGVLEVYRIGQRQ--------WM-PA----------CVKNWDRAVSPSAV 1021
            ..|||         .|    :|...|..        || ||          ....|.|....|..
  Fly   333 VEGDVFQYEDFDLPDT----MYADSQESEGEFRNITWMQPAKDGIALRRRKVYSKWSRWTKCSPK 393

  Fly  1022 CSILGYSAVN-----ATSVL------------------TQLTHRPLLAT----VNVSTDIWKMYA 1059
            |:...|....     ...||                  ||....|...|    .:.:..:.:|.:
  Fly   394 CTTRRYKKCRIMDQCGREVLREIAYCYTEGSFCQQWLQTQFQKTPAFETRPGSGSPANAMRRMQS 458

  Fly  1060 KRKSTLMQEFANCKKTEDYPMADLTCSNYECGRVKRGRHKPSR----RIIGGTQASPGNWPFLAA 1120
            ::....|.:.......:.|...:.|.....||.|:.|..:.|.    :||||..|..|.||:..|
  Fly   459 EQPEVSMNDLNYIMTGKGYRGPEYTPLKLSCGIVRSGTGRRSMSNMLKIIGGRAARKGEWPWQVA 523

  Fly  1121 ILGGPEKIFYCAGVLISDQWVLTASHCV--------GNYSVIDLEDWT-IQLGVTRRNSFTYSGQ 1176
            ||...::.| |.|.||:.:|||||:|||        |.:: ::.||.| |||.|.:  |:|
  Fly   524 ILNRFKEAF-CGGTLIAPRWVLTAAHCVRKVLFVRIGEHN-LNYEDGTEIQLRVMK--SYT---- 580

  Fly  1177 KVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKR 1241
                     ||.::.... |:|:||.:|...|.....:...|||.| .:.|.....||:||||||
  Fly   581 ---------HPNFDKRTV-DSDVALLRLPKAVNATTWIGYSCLPQP-FQALPKNVDCTIIGWGKR 634

  Fly  1242 EDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYP 1306
            .::|...|  .::::..||||....|.:...:.|:::.|.|||...|..|.|.|||||||||...
  Fly   635 RNRDATGT--SVLHKATVPIIPMQNCRKVYYDYTITKNMFCAGHQKGHIDTCAGDSGGPLLCRDT 697

  Fly  1307 GEKNR-WFVGGIVSWGIMCAHPRLPGVYANVVQYVPWI 1343
            .:.|. |.:.||.|:|..||.....|:||.|..||.|:
  Fly   698 TKPNHPWTIFGITSFGDGCAQRNKFGIYAKVPNYVDWV 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	26/137 (19%)
		LDLa	911..942	CDD:238060	4/30 (13%)
		LDLa	945..979	CDD:238060	5/33 (15%)
		SR	980..>1034	CDD:214555	16/86 (19%)
		Tryp_SPc	1104..1346	CDD:238113	94/250 (38%)
CG10663	NP_001097592.1	Tryp_SPc	506..735	CDD:214473	93/249 (37%)