DRSC/TRiP Functional Genomics Resources

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Protein Alignment Corin and CG1299

DIOPT Version :10

Sequence 1:NP_610297.2 Gene:Corin / 35691 FlyBaseID:FBgn0033192 Length:1397 Species:Drosophila melanogaster
Sequence 2:NP_647862.1 Gene:CG1299 / 38496 FlyBaseID:FBgn0035501 Length:511 Species:Drosophila melanogaster


Alignment Length:409 Identity:115/409 - (28%)
Similarity:179/409 - (43%) Gaps:101/409 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   973 GQDER--NCLRLSERNGDVGTGVLEVYRIGQRQWMPACVKNWDRAVSP------SAVCSILGYSA 1029
            |.|.:  ||:.:.|     ...:|...|...:.   |...|:.||.:.      :.||...|...
  Fly   166 GPDTKPGNCVEIKE-----CASLLNELRSRSQD---ATFANFLRASNAVCQNKGTQVCCPTGQGI 222

  Fly  1030 VNATSVLTQLTHRPLLATVNVSTDIWKMYAKRKSTLMQEFANCKKTEDYPMADLTCSNYE--CGR 1092
            .|.|...:|:..                               |.|::.|...|   |.|  ||.
  Fly   223 TNTTPAPSQIVP-------------------------------KNTDEIPRRLL---NVEEGCGS 253

  Fly  1093 VKRGRHKPSRRIIGGTQASPGNWPFLAAI-----LGGPEKIFYCAGVLISDQWVLTASHCVGNYS 1152
            .. |..|   :|:||..:..|.||::|.:     .|.|   |.|.|.||:.:.||||:||:..  
  Fly   254 TV-GYFK---KIVGGEVSRKGAWPWIALLGYDDPSGSP---FKCGGTLITARHVLTAAHCIRQ-- 309

  Fly  1153 VIDLEDWTIQLGVTRRNSFTYSGQ-KVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLP 1216
              ||:  .::||....::.|.:|. .:.:...:.||.||..... :|:|:..|...|.|...:.|
  Fly   310 --DLQ--FVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGR-SDMAILYLERNVEFTSKIAP 369

  Fly  1217 VCLPPPSVRNL----HPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQC---------- 1267
            :||  |...||    :.|.:..|.||||..:....:   .::||:|:||.....|          
  Fly   370 ICL--PHTANLRQKSYVGYMPFVAGWGKTMEGGESA---QVLNELQIPIYDNKVCVQSYAKEKRY 429

  Fly  1268 ---DEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGE-KNRWFVGGIVSWGIMCAHPR 1328
               |::      .:.::|||...||||.|||||||||:.|.|.: :.|:::.|:||:||.||.|.
  Fly   430 FSADQF------DKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPN 488

  Fly  1329 LPGVYANVVQYVPWIQEQI 1347
            :||||::...::.||.:|:
  Fly   489 VPGVYSSTQYFMDWIIQQV 507

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CorinNP_610297.2 CRD_FZ 778..894 CDD:143549
LDLa 911..942 CDD:238060
LDLa 945..979 CDD:238060 2/7 (29%)
SR 980..>1034 CDD:214555 11/59 (19%)
Tryp_SPc 1104..1346 CDD:238113 87/265 (33%)
CG1299NP_647862.1 CLIP 37..92 CDD:463440
CLIP 164..216 CDD:463440 12/57 (21%)
Tryp_SPc 261..503 CDD:238113 85/262 (32%)
Blue background indicates that the domain is not in the aligned region.

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