Protein Alignment Corin and Np

DIOPT Version :9

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001246213.1
• Gene: Np / 35904
• FlyBaseID: FBgn0265011
• Length: 1041
• Species: Drosophila melanogaster
• Alignment Length: 1054
• Identity: 223/1054 - (21%)
• Similarity: 362/1054 - (34%)
• Gaps: 264/1054 - (25%)

  Fly   405 PPVKGSSNSSNSIGETQSQSSKEPSS----VSASASTSSAASAGSST---------ISSGTMSSM 456
            |.:..:|...|:|.....:|:..|:|    ::..:|.||::|:||||         :.:.|.|.:
  Fly   135 PEINDNSIDQNTISHFSHESTTLPTSALFKLTTESSLSSSSSSGSSTAHHHTTNELLKNVTQSYL 199

  Fly   457 SGPCPAVVPPTD----AITKRPGPPEPPLRQANVFDPVETGSRGHPPPPLTV-------RNKLGR 510
            |...||.|..|.    :.|:|  ||.......|....|.|..:....|..|:       |.:...
  Fly   200 STAKPAPVRTTSNGTLSTTRR--PPLAHTTHKNSHYVVRTTMKPSAAPTTTITPTVKPPRRRTTT 262

  Fly   511 NKPPPITYPRMQQRQDSTLSSDSYSI-----SSSPGYN--SKLMEAPLLGSQQGGRKSNAPGSAQ 568
            .||...|.|.::||.::|.....:..     :::|...  :...|.....:::..|.:.:...|.
  Fly   263 AKPVLTTAPIVEQRIETTSVPTKFVTFQIVETTTPAVTEPTHQQETTTTTTRRHTRPTGSSSVAS 327

  Fly   569 RQTPLMDLAPTRFLGGAGGGTGSGKQGPAMPPPRSKINFRQDSTISSDSFSQTSSPGYNPKLMEA 633
            |.|.......|           :.....|.||          :|.|:.:.:.|..|  .|.|...
  Fly   328 RTTSKTTTTTT-----------TTTTTTAAPP----------TTTSTRAATTTQRP--TPPLRTT 369

  Fly   634 PLLP--SLSAKRLCSAPAPI----VCRQGVQ--HEPIEELEPPQTIS--------PLHKAAGQPS 682
            ...|  :.|::|...|..|:    ....|.|  .:|.:.|....|.:        |..:...|.|
  Fly   370 TSKPHKTHSSRRPAPAKKPVSTTTTTASGTQSTRKPADSLASGSTTANGTTATTLPARRPVTQTS 434

  Fly   683 SLQTIVRFQNGAPHTMSLQHQIINRRKSSNPYITNGRLKFRLFQI----------LINAFALLA- 736
            |..|..........|...:.::...|       |..||..|..|.          ::...||||
  Fly   435 SSSTTTTSTTSTITTTVFKDELPKNR-------TTTRLPERTTQAPRPRPKPTGEIVKVPALLAE 492

  Fly   737 -----IAGGLAAYFNAYP------TIKFVNKTIINTIHVEDTTSFGKNPAPGTCLPIIVRFCQGP 790
                 :..|.::..::.|      |...|.|....|.:...||:........|..|...|..:.|
  Fly   493 PTTTTVTKGSSSSSSSSPKPPASSTTPLVTKKKPTTTNAPTTTTTTTTTTTTTTTPKPTRRTKPP 557

  Fly   791 QIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLCTLFVPKCGQSGATVPPCKTL 855
            ......|.            ..|...:...........|::                |.||....
  Fly   558 TTTTTTTT------------KATTTTTKATTTTTTAKPLIT----------------TEPPTSAP 594

  Fly   856 CTETMRRCGF--FFDVFGLSLPEYLNCKLFKDF----PSSEDCVGLDEVREVMRAATHPKCDGFQ 914
            .|.|.::.|.  :.||   ......|..:..|:    ||:
  Fly   595 LTTTTKKTGLITWTDV---EAEPPTNASISNDWQPAPPSN------------------------- 631

  Fly   915 CDQNRCLPQEYVCDGHLDCMDQADEAKCERCGPDEIYCGDSQCIGTKHICDGIIDCPYGQDERNC 979
                 .||..      .:..:.||:.......|.              ..|.::.
  Fly   632 -----WLPLT------TESSETADKTSASTAPPS--------------ATDKVVI---------- 661

  Fly   980 LRLSERNGDVGTGVLEVYRIGQRQWMPACVKNWDRAVSPSAVCSILGYSAVNATSVLTQLTHRP- 1043
                    .|.|.|.||...|     |...:...:...||:.......:...||::: :.|..|
  Fly   662 --------SVATSVSEVETHG-----PGKPQKTTKPPKPSSTAKPTTTTTAAATTIV-KTTEAPA 712

  Fly  1044 ----LLATVNVSTDIWKMYAKRKS----TLMQEFANCKKTEDY-------------------PMA 1081
                |.::.:..||:....|...|    |.........:|.||                   |..
  Fly   713 SSIELASSTSSYTDLGSDLAASSSSSTTTTTSSPTTAAETTDYSGEEPNTTTIEATGSTTVAPAN 777

  Fly  1082 DLTCSNYE--CGRVKRGRHKPSRRIIGGTQASPGNWPFLAAILGGPEKIFY--CAGVLISDQWVL 1142
            .|...:|:  |||    |..|..||:||..|:.|.||:..::.......:.  |...|:::.|.:
  Fly   778 ALEGVDYKEVCGR----RMFPEPRIVGGANAAFGRWPWQISLRQWRTSTYLHKCGAALLNENWAI 838

  Fly  1143 TASHCVGNYSVIDLEDWTIQLGV--TRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLA 1205
            ||:|||.|....||   .::||.  .......|..|:.:|:.|..|||::.. ..:.|:||.:..
  Fly   839 TAAHCVDNVPPSDL---LLRLGEYDLAEEEEPYGYQERRVQIVASHPQFDPR-TFEYDLALLRFY 899

  Fly  1206 TRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEW 1270
            ..|.|..:::|||:|......:  |....|.|||:..:..|..:   ::.||.||:|....|:..
  Fly   900 EPVIFQPNIIPVCVPDNDENFI--GQTAFVTGWGRLYEDGPLPS---VLQEVAVPVINNTICESM 959

  Fly  1271 LDNLTVSEGM----VCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPG 1331
            ..:....|.:    :|||:..||.|:|:||||||::.....:| |:.:||::||||.||....||
  Fly   960 YRSAGYIEHIPHIFICAGWKKGGYDSCEGDSGGPMVLQRESDK-RFHLGGVISWGIGCAEANQPG 1023

  Fly  1332 VYANVVQYVPWIQE 1345
            ||..:.::..||.:
  Fly  1024 VYTRISEFRDWINQ 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	19/121 (16%)
		LDLa	911..942	CDD:238060	4/30 (13%)
		LDLa	945..979	CDD:238060	2/33 (6%)
		SR	980..>1034	CDD:214555	10/53 (19%)
		SRCR	992..1086	CDD:278931	22/121 (18%)
		Tryp_SPc	1103..1343	CDD:214473	77/247 (31%)
		Tryp_SPc	1104..1346	CDD:238113	78/250 (31%)
Np	NP_001246213.1	Tryp_SPc	797..1035	CDD:214473	77/247 (31%)
		Tryp_SPc	798..1038	CDD:238113	78/250 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010