Protein Alignment Corin and PRSS51

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_047278465.1
• Gene: PRSS51 / 346702
• HGNCID: 37321
• Length: 265
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 78/278 - (28%)
• Similarity: 126/278 - (45%)
• Gaps: 41/278 - (14%)

  Fly  1076 EDYPMADLTCSNYECGRVKRGRHKPS----------RRIIGGTQASPGNWPFLAAILGGPEKIFY 1130
            :|.|      .|.:||      |:|:          .|:    |...|..|:..:|....:.:
Human    17 QDNP------ENVQCG------HRPAFPNSSWLPFHERL----QVQNGECPWQVSIQMSRKHL-- 63

  Fly  1131 CAGVLISDQWVLTASHCVGNYSVIDLE--DWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAI 1193
            |.|.::...|||||:||. ..:::|:.  :.|:.:| ||..|..:|.:| :|:.||.|..|...
Human    64 CGGSILHWWWVLTAAHCF-RRTLLDMAVVNVTVVMG-TRTFSNIHSERK-QVQKVIIHKDYKPP- 124

  Fly  1194 AHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQ 1258
            ..|:|::|..|||.|.|....:||||....    .....|.:..|......|........:.:::
Human   125 QLDSDLSLLLLATPVQFSNFKMPVCLQEEE----RTWDWCWMAQWVTTNGYDQYDDLNMHLEKLR 185

  Fly  1259 VPIITRNQCDEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIM 1323
            |..|:|.:|.:.::.|  |..|:||..:.|.....:||||.||:|...|.: |.|..|:.|.||.
Human   186 VVQISRKECAKRINQL--SRNMICAWNEPGTNGIFKGDSGAPLVCAIYGTQ-RLFQVGVFSGGIR 247

  Fly  1324 CAHPRLPGVYANVVQYVP 1341
            ......||::.:|.|::|
Human   248 SGSRGRPGMFVSVAQFIP 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	70/240 (29%)
PRSS51	XP_047278465.1	Tryp_SPc	45..265	CDD:214473	68/232 (29%)