Protein Alignment Corin and OVCH2

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_047282834.1
• Gene: OVCH2 / 341277
• HGNCID: 29970
• Length: 569
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 89/270 - (32%)
• Similarity: 140/270 - (51%)
• Gaps: 37/270 - (13%)

  Fly  1103 RIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTR 1167
            ||:||:|...|::|:..::....:.|  |.|.::|.|||:||:||:.|.:::.      .|.||.
Human    55 RILGGSQVEKGSYPWQVSLKQRQKHI--CGGSIVSPQWVITAAHCIANRNIVS------TLNVTA 111

  Fly  1168 RN---SFTYSG-QKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPPPSVR-NL 1227
            ..   |.|..| |.:.::.||.||.::.....|.||||.::|....|...:.|:||  |.:| ..
Human   112 GEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICL--PELREQF 174

  Fly  1228 HPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTV-----SEGMVCAGFDD 1287
            ..|.:||..|||:..:   ......::.||.:||:|..:|...|  ||:     .:..:|.||.|
Human   175 EAGFICTTAGWGRLTE---GGVLSQVLQEVNLPILTWEECVAAL--LTLKRPISGKTFLCTGFPD 234

  Fly  1288 GGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMC----------AHPRLPGVYANVVQYVPW 1342
            ||:|||||||||.|:|  ..:|..|.:.|:.|||:.|          :....||::.::.:.:||
Human   235 GGRDACQGDSGGSLMC--RNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPW 297

  Fly  1343 IQEQIAKHSR 1352
            |.|.|...:|
Human   298 IHEHIQTGNR 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	85/261 (33%)
OVCH2	XP_047282834.1	Tryp_SPc	56..301	CDD:238113	85/261 (33%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001