Protein Alignment Corin and Prss34

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_848459.1
• Gene: Prss34 / 328780
• MGIID: 2681414
• Length: 318
• Species: Mus musculus
• Alignment Length: 286
• Identity: 97/286 - (33%)
• Similarity: 142/286 - (49%)
• Gaps: 47/286 - (16%)

  Fly  1104 IIGGTQASPGNWPFLAAILGGPEKIF---------YCAGVLISDQWVLTASHCVGNYSVIDLEDW 1159
            |:||...|...:|:..::     :::         .|.|.||..||||||:||| ....::....
Mouse    35 IVGGCPVSASRFPWQVSL-----RLYDMEHSRWEHECGGSLIHPQWVLTAAHCV-RPKEVEAYGV 93

  Fly  1160 TIQLGVTRRNSFTYSGQKVKVKAVIPHPQYN--MAIAHDNDIALFQLATRVAFHEHLLPVCLPPP 1222
            .:|:|..|   ...:.|.:||..:|.||:::  ::.....||||.:|.|||...||:.||.||..
Mouse    94 RVQVGQLR---LYENDQLMKVVKIIRHPKFSEKLSARGGADIALLKLDTRVVLSEHVYPVSLPAA 155

  Fly  1223 SVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWL------DNLT--VSEG 1279
            |:| :.....|.|.|||..|:..|... .|.:.||.|||:..|.|::..      |:.|  :.:.
Mouse   156 SLR-ISSKKTCWVAGWGVIENYMPLPP-PYHLREVAVPIVENNDCEQKYQTNSSSDSTTRIIKDD 218

  Fly  1280 MVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQ 1344
            |:|||.:  |:|:|:.||||||:|.:   ...|...|:|||||.|..|..||||..|:.||.||:
Mouse   219 MLCAGKE--GRDSCKADSGGPLVCRW---NCSWVQVGVVSWGIGCGLPDFPGVYTRVMSYVSWIK 278

  Fly  1345 EQIAKHSRPIKEDRVNKYDLHPGGPD 1370
            ..:.....|:|            |||
Mouse   279 CYVPTFLEPLK------------GPD 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	92/260 (35%)
Prss34	NP_848459.1	Tryp_SPc	35..278	CDD:238113	91/258 (35%)