DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Corin and Loxl3

DIOPT Version :9

Sequence 1:NP_610297.2 Gene:Corin / 35691 FlyBaseID:FBgn0033192 Length:1397 Species:Drosophila melanogaster
Sequence 2:NP_001101336.1 Gene:Loxl3 / 312478 RGDID:1311011 Length:754 Species:Rattus norvegicus


Alignment Length:239 Identity:49/239 - (20%)
Similarity:81/239 - (33%) Gaps:91/239 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   957 CIGTK-HI---------------CDG----IIDCPYG-----------------QDERNCLRLSE 984
            |:||: |:               |.|    ::.|..|                 |.|.: :|| :
  Rat   249 CVGTEAHLSLCSLEFYRANDTTRCAGGSPAVVSC
MLGPLYATSTGQKKQQHSKPQGEAS-VRL-K 311

  Fly   985 RNGDVGTGVLEVYRIGQRQWMPACVKNWDRAVSPSAVCSILGYSAVNATSVLTQLTHRPLLATVN 1049
            .....|.|.:||.:.|  .|...|.:.||...: |.||..||:.  .|...|:.......:..::
  Rat   312 GGAHPGEGRVEVLKAG--TWGTVCDRKWDLQAA-SVVCRELGFG--TAREALSGARMGQGMGAIH 371

  Fly  1050 VS--------TDIWKMYAKRKSTLMQEFANCKKTEDYPMADLTCSNYECG-----RVKRGRHKPS 1101
            :|        ..:||..:|..:.     .:|..::|   |.:.|:....|     |:..||.:..
  Rat   372 LSEVRCSGQEPSLWKCPSKNITA-----EDCSHSQD---AAVRCNLPYTGVETKIRLSGGRSRYE 428

  Fly  1102 RRI---IGGTQASPGN--WPFLAAILGGPEKIFYCAGVLISDQW 1140
            .|:   ||    .||:  |                 |::..|.|
  Rat   429 GRVEVQIG----VPGHLRW-----------------GLICGDDW 451

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CorinNP_610297.2 CRD_FZ 778..894 CDD:143549
LDLa 911..942 CDD:238060
LDLa 945..979 CDD:238060 10/58 (17%)
SR 980..>1034 CDD:214555 17/53 (32%)
SRCR 992..1086 CDD:278931 22/101 (22%)
Tryp_SPc 1103..1343 CDD:214473 9/43 (21%)
Tryp_SPc 1104..1346 CDD:238113 8/42 (19%)
Loxl3NP_001101336.1 SR 46..145 CDD:214555
SRCR 54..146 CDD:278931
SR 170..282 CDD:214555 6/32 (19%)
SRCR 187..282 CDD:278931 6/32 (19%)
SR 308..408 CDD:214555 25/113 (22%)
SRCR 313..408 CDD:278931 23/107 (21%)
SR 418..526 CDD:214555 12/55 (22%)
SRCR 423..526 CDD:278931 11/50 (22%)
Lysyl_oxidase 531..725 CDD:279521
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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