Protein Alignment Corin and Tmprss11e

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001406557.1
• Gene: Tmprss11e / 305265
• RGDID: 1561698
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 281
• Identity: 96/281 - (34%)
• Similarity: 138/281 - (49%)
• Gaps: 28/281 - (9%)

  Fly  1068 EFANCKKTE--DYPMADLTCSNYECG-RVKRGRHKPSRRIIGGTQASPGNWPFLAAI-LGGPEKI 1128
            |.....|||  :|       .|:.|| |..:...:.|.||:|||.|..|.||:.::: ..|..:
  Rat   160 EIKKINKTESDNY-------LNHCCGTRRNKSTAQTSVRIVGGTSAEEGEWPWQSSLQWDGSHR- 216

  Fly  1129 FYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAI 1193
              |...|||:.|:::|:||...:.  |...||...|.|.:.....:|    ::.:|.|.:||..
  Rat   217 --CGATLISNTWLVSAAHCFRTHK--DPSRWTASFGATLQPPKLTTG----IRRIIVHEKYNYP- 272

  Fly  1194 AHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQ 1258
            :||.||||.:|:..|.....:..||||..: ....||....|.|:|...:......|   :.:||
  Rat   273 SHDYDIALVELSRPVPCTNAVHKVCLPDAN-HEFQPGQRMFVTGFGALRNDGFAQNY---LRQVQ 333

  Fly  1259 VPIITRNQCDEWLD-NLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGI 1322
            |..|....|:.... |..::..|:||||..|.||||||||||||:.  |..::.|::.|:||||.
  Rat   334 VDYIDTQTCNRPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVT--PDVRDVWYLAGVVSWGD 396

  Fly  1323 MCAHPRLPGVYANVVQYVPWI 1343
            .|..|..||||..|..:..||
  Rat   397 ECGQPNKPGVYTRVTAFRDWI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	85/242 (35%)
Tmprss11e	NP_001406557.1	SEA	50..146	CDD:460188
		Tryp_SPc	192..420	CDD:238113	85/242 (35%)