DRSC/TRiP Functional Genomics Resources

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Protein Alignment Corin and PRSS50

DIOPT Version :9

Sequence 1:NP_610297.2 Gene:Corin / 35691 FlyBaseID:FBgn0033192 Length:1397 Species:Drosophila melanogaster
Sequence 2:NP_037402.1 Gene:PRSS50 / 29122 HGNCID:17910 Length:385 Species:Homo sapiens


Alignment Length:357 Identity:91/357 - (25%)
Similarity:147/357 - (41%) Gaps:66/357 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly  1012 WDRAVSPSAVCSI-LGYSAVNATSVLTQLTHRPLLATVNVSTDIWKMYAKR--KSTLMQEFANCK 1073
            |....:|.|:.:. ....:|......|..:.||.|        :|:....:  .||.|:      
Human    38 WGAGEAPGALSTADPADQSVQCVPKATCPSSRPRL--------LWQTPTTQTLPSTTME------ 88

  Fly  1074 KTEDYPMAD------LTCS-NYECGRVKRGRHKPSRRIIGGTQASPGNWPFLAAILGGPEKIFYC 1131
              ..:|:::      .:|. :||.....|.....:||           ||::.::......|  |
Human    89 --TQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAVARR-----------WPWMVSVRANGTHI--C 138

  Fly  1132 AGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMA---- 1192
            ||.:|:.|||||.:||:....||    :::::|....:..|.:...|.|..||.|.:|...    
Human   139 AGTIIASQWVLTVAHCLIWRDVI----YSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWS 199

  Fly  1193 -IAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWG--KREDKDPKSTYEYIV 1254
             :...|||.|.:|...:.:..::.|:|||.... .|...:.|||.|||  |.:...|:..   .:
Human   200 WVGQANDIGLLKLKQELKYSNYVRPICLPGTDY-VLKDHSRCTVTGWGLSKADGMWPQFR---TI 260

  Fly  1255 NEVQVPIITRNQCDEWLDNLT--------VSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNR 1311
            .|.:|.|:...:||.:..|.|        :...|:||. |...:..|...:|.||:|...|   .
Human   261 QEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAE-DTHREKFCYELTGEPLVCSMEG---T 321

  Fly  1312 WFVGGIVSWGIMCAHPRLPGVYANVVQYVPWI 1343
            |::.|:||||..|.....|.:|..|..|..||
Human   322 WYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CorinNP_610297.2 CRD_FZ 778..894 CDD:143549
LDLa 911..942 CDD:238060
LDLa 945..979 CDD:238060
SR 980..>1034 CDD:214555 4/22 (18%)
SRCR 992..1086 CDD:278931 13/82 (16%)
Tryp_SPc 1103..1343 CDD:214473 71/254 (28%)
Tryp_SPc 1104..1346 CDD:238113 72/255 (28%)
PRSS50NP_037402.1 Tryp_SPc 118..353 CDD:238113 72/259 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24253
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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