Protein Alignment Corin and Loxl2

DIOPT Version :9

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_038949076.1
• Gene: Loxl2 / 290350
• RGDID: 1308435
• Length: 823
• Species: Rattus norvegicus
• Alignment Length: 586
• Identity: 121/586 - (20%)
• Similarity: 179/586 - (30%)
• Gaps: 240/586 - (40%)

  Fly   870 FGLSLPEYLNCKLFKDFPSS--EDCVGLDEVREVMRAATHPKCDGFQCDQNRCLPQEY------- 925
            :.|..|||     |:..|..  :..|..|.|:..:|.|      |.:...|....:.|
  Rat    44 YQLQYPEY-----FQQPPPEHHQHQVPSDVVKIQVRLA------GQKRKHNEGRVEVYYEGQWGT 97

  Fly   926 VCD-------GHLDCMDQA-DEAK----CERCGP-------DEIYCGDSQCIGTKHICD----GI 967
            |||       .|:.|.:.. .|||    ....||       |.|||...:  .|...|.    |:
  Rat    98 VCDDDFSIHAAHVVCREVGYVEAKSWTASSSYGPGEGPIWLDNIYCTGKE--STLAACSSNGWGV 160

  Fly   968 IDCPYGQDE----------------------------------RNCLRLSERNGDVGTGVLEVYR 998
            .||.:.:|.                                  |..|........|..|.:||..
  Rat   161 TDCKHTEDVGVVCSEKRIPGFKFDNSLINQIESLNIQVEDIRIRPILSAFRHRKPVTEGYVEVKE 225

  Fly   999 IGQRQWMPACVKNWDRAVSPSAVCSILGYSAVNATSVLTQLTHRPLLATVNVSTDIWKMYAKRKS 1063
              .:.|...|.|:| .|.:...||.:.|:.|        :.|:.|         ..:|.:|.|:.
  Rat   226 --GKAWKQICDKHW-TAKNSHVVCGMFGFPA--------EKTYNP---------KAYKTFASRRK 270

  Fly  1064 TLMQEFA-NCKKTEDY-------------PMADLTCSNYECGRVK---------------RGRHK 1099
            ....:|: ||..||.:             |:.:.||.|.:...|.               |..:|
  Rat   271 LRYWKFSMNCTGTEAHISSCKLGPPMFRDPVKNATCENGQPAVVSCVPSQIFSPDGPSRFRKAYK 335

  Fly  1100 PSR----------RIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASHCVGNYSVI 1154
            |.:          |:.||.|...|.    ..:|...|     .|.:..|:|.|.::      ||:
  Rat   336 PEQDHVSLQQPLVRLRGGAQVGEGR----VEVLKNGE-----WGTVCDDKWDLVSA------SVV 385

  Fly  1155 DLEDWTIQLGV-TRRNSFTYS--GQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLP 1216
            ..|     ||. |.:.:.|.|  ||.:..       :|...                   :|.:|
  Rat   386 CRE-----LGFGTAKEAVTGSRLGQGIGW-------EYTEG-------------------KHGIP 419

  Fly  1217 VCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWLD------NLT 1275
            ..|    :.....|:.||.||             ...:||||.....::..|..|:      |..
  Rat   420 ALL----LGKASSGSECTGIG-------------PIHLNEVQCTGTEKSIIDCKLNTESQGCNHE 467

  Fly  1276 VSEGMVC----AGFD-----DGGKDACQGDSGGPLLCPYPG------EKNRWFVGGIV---SWGI 1322
            ...|:.|    .||.     :||::            ||.|      |:|...|.|.|   :|||
  Rat   468 EDAGVRCNIPIMGFQKKVRLNGGRN------------PYEGRVEVLTERNGSLVWGNVCGQNWGI 520

  Fly  1323 M 1323
            :
  Rat   521 V 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	6/25 (24%)
		LDLa	911..942	CDD:238060	11/49 (22%)
		LDLa	945..979	CDD:238060	13/78 (17%)
		SR	980..>1034	CDD:214555	14/53 (26%)
		SRCR	992..1086	CDD:278931	24/107 (22%)
		Tryp_SPc	1103..1343	CDD:214473	54/248 (22%)
		Tryp_SPc	1104..1346	CDD:238113	53/247 (21%)
Loxl2	XP_038949076.1	SR	73..174	CDD:214555	25/108 (23%)
		SR	216..316	CDD:214555	28/119 (24%)
		SR	348..475	CDD:214555	38/189 (20%)
		SR	485..593	CDD:214555	13/49 (27%)
		Lysyl_oxidase	598..797	CDD:395944

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000