Protein Alignment Corin and TMPRSS11E

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_054777.2
• Gene: TMPRSS11E / 28983
• HGNCID: 24465
• Length: 423
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 92/277 - (33%)
• Similarity: 139/277 - (50%)
• Gaps: 29/277 - (10%)

  Fly  1071 NCKKTEDYPMADLTCSNYECGRVKRGRHKPSRRIIGGTQASPGNWPFLAAI-LGGPEKIFYCAGV 1134
            |..:|:.|       .|:.||..:......|.||:|||:...|.||:.|:: ..|..:   |...
Human   166 NKTETDSY-------LNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHR---CGAT 220

  Fly  1135 LISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVK--VKAVIPHPQYNMAIAHDN 1197
            ||:..|:::|:||...|.  :...||...|||.:.|      |:|  ::.:|.|.:|... :||.
Human   221 LINATWLVSAAHCFTTYK--NPARWTASFGVTIKPS------KMKRGLRRIIVHEKYKHP-SHDY 276

  Fly  1198 DIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPII 1262
            ||:|.:|::.|.:...:..||||..|. ...||.:..|.|:|..::......:   :.:.||.:|
Human   277 DISLAELSSPVPYTNAVHRVCLPDASY-EFQPGDVMFVTGFGALKNDGYSQNH---LRQAQVTLI 337

  Fly  1263 TRNQCDE-WLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAH 1326
            ....|:| ...|..::..|:|||..:|..|||||||||||:.  ...::.|::.||||||..||.
Human   338 DATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVS--SDARDIWYLAGIVSWGDECAK 400

  Fly  1327 PRLPGVYANVVQYVPWI 1343
            |..||||..|.....||
Human   401 PNKPGVYTRVTALRDWI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	84/244 (34%)
TMPRSS11E	NP_054777.2	SEA	51..147	CDD:460188
		Tryp_SPc	192..420	CDD:238113	84/244 (34%)