Protein Alignment Corin and f7i

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_775335.2
• Gene: f7i / 282671
• ZFINID: ZDB-GENE-021206-10
• Length: 443
• Species: Danio rerio
• Alignment Length: 309
• Identity: 87/309 - (28%)
• Similarity: 135/309 - (43%)
• Gaps: 44/309 - (14%)

  Fly  1071 NCKKTEDYPMAD--LTC---SNYECGRVKRGRHKPSRRIIGGTQASPGNWPFLAAILGGPEKIFY 1130
            :|...|.|.:||  .:|   .:|.||::...::....:.:||.....|:.|:...|....|.:
Zfish   148 SCSCAEGYALADDGTSCVSQVDYPCGKIPVQKNTSQNQFLGGIHCPRGHCPWQVLIDYNGESV-- 210

  Fly  1131 CAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTY---SGQKVKVKAVIPHPQYNMA 1192
            |.|.|:...|::||:|||..      :|......||..:....   |.:..:|.||..||.|:..
Zfish   211 CGGALLEGPWLITAAHCVHQ------KDTRFLKAVTGEHDLDVLDGSEEPYEVSAVFIHPNYDPE 269

  Fly  1193 IAHDNDIALFQLATRVAFHEHLLPVCLPPPSV--RNLHPGTLCTVIGWGK-------REDKDPKS 1248
            .. |:|:||.:|...|....:.:|:|||.|.:  ..|......|:.|||.       |.:|..|.
Zfish   270 TL-DSDLALLRLRVPVQRSLYAVPICLPTPQLARSELWAARFHTLSGWGTRTAGHNLRREKGLKG 333

  Fly  1249 TYEYIVNEVQVPIITRNQCDEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWF 1313
            .....:..:.||::...||    .|...:..|.|||:.:|...:|:|..|.||:..| ||.:  |
Zfish   334 PASGTLQRLAVPLLPAAQC----GNANTTANMFCAGYTEGDHASCRGHDGSPLVTRY-GETS--F 391

  Fly  1314 VGGIVSWGIMCAHPRLPGVYANVVQYVPWI-----------QEQIAKHS 1351
            :.|:||||..|..|....:|..|..::.|:           .||||..|
Zfish   392 LTGVVSWGRGCGPPGYYWIYTKVENFLIWMDTVMKTNTEDKSEQIANVS 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	73/264 (28%)
f7i	NP_775335.2	GLA	20..82	CDD:214503
		EGF_CA	<91..120	CDD:238011
		FXa_inhibition	129..164	CDD:464251	5/15 (33%)
		Tryp_SPc	188..420	CDD:238113	72/247 (29%)