DRSC/TRiP Functional Genomics Resources

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Protein Alignment Corin and Fzd6

DIOPT Version :9

Sequence 1:NP_610297.2 Gene:Corin / 35691 FlyBaseID:FBgn0033192 Length:1397 Species:Drosophila melanogaster
Sequence 2:NP_001124008.1 Gene:Fzd6 / 282581 RGDID:628816 Length:710 Species:Rattus norvegicus


Alignment Length:196 Identity:57/196 - (29%)
Similarity:83/196 - (42%) Gaps:30/196 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   778 TCLPIIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLCTLFVPKC 842
            ||.||.|..|.  ::.||.|.|||.:||:.|.....:::.:..|.::.|...:.:|||..|||.|
  Rat    23 TCEPITVPRCM--KMAYNMTFFPNLMGHYDQGIAAVEMEHFLPLANLECSPNIEMFLCQAFVPTC 85

  Fly   843 GQSGATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSEDCVGL--DEVREVM--- 902
            .:....|.||:.||.:.:..|....|.||:..||.|.|   ...|..:..|.:  |...|:.   
  Rat    86 TEQIDVVSPCRKLCEKILSDCQKLMDTFGIRWPEELEC---HRLPYCDGAVPVTSDPHTELFGPQ 147

  Fly   903 -RAATHPKCDGFQC--------DQ-------NRCLPQEYVCDGHLDCMDQADEAKCERCGPDEIY 951
             :....|:..||.|        ||       ::|.|.   |.......|:.|.|| ...|...|:
  Rat   148 KKTDQVPRDIGFWCPKHLRTSGDQGYRFLGIDQCAPP---CPNMYFKSDELDFAK-SFIGIVSIF 208

  Fly   952 C 952
            |
  Rat   209 C 209

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CorinNP_610297.2 CRD_FZ 778..894 CDD:143549 38/115 (33%)
LDLa 911..942 CDD:238060 11/45 (24%)
LDLa 945..979 CDD:238060 3/8 (38%)
SR 980..>1034 CDD:214555
SRCR 992..1086 CDD:278931
Tryp_SPc 1103..1343 CDD:214473
Tryp_SPc 1104..1346 CDD:238113
Fzd6NP_001124008.1 CRD_FZ6 20..146 CDD:143559 41/127 (32%)
7tmF_FZD6 188..508 CDD:320160 7/23 (30%)
TM helix 1 198..222 CDD:320160 5/13 (38%)
TM helix 2 231..252 CDD:320160
TM helix 3 283..305 CDD:320160
TM helix 4 326..342 CDD:320160
TM helix 5 364..387 CDD:320160
TM helix 6 418..440 CDD:320160
TM helix 7 469..494 CDD:320160
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3577
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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