Protein Alignment Corin and KLK13

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 88/249 - (35%)
• Similarity: 124/249 - (49%)
• Gaps: 25/249 - (10%)

  Fly  1106 GGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNS 1170
            ||....|.:.|:.||:|  .:....|.|||:..:|||||:||:       .|...:.||......
Human    38 GGYTCFPHSQPWQAALL--VQGRLLCGGVLVHPKWVLTAAHCL-------KEGLKVYLGKHALGR 93

  Fly  1171 FTYSGQKVKVKAVIPHPQYNMA---IAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTL 1232
            .....|..:|...||||:|..:   :.||:||.|.:|.:.|....::  ..||......|.|||.
Human    94 VEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYI--QTLPLSHNNRLTPGTT 156

  Fly  1233 CTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTVSEGMVCAGFDDGGKDACQGDS 1297
            |.|.|||  ....|:..|...:....:.:.:..:|.:.... .:::.|:|||..:||||:|:|||
Human   157 CRVSGWG--TTTSPQVNYPKTLQCANIQLRSDEECRQVYPG-KITDNMLCAGTKEGGKDSCEGDS 218

  Fly  1298 GGPLLCPYPGEKNRWFVGGIVSWG-IMCAHPRLPGVYANVVQYVPWIQEQIAKH 1350
            ||||:|      ||... |||||| ..|..|..||||..|.:||.||:|.|.|:
Human   219 GGPLVC------NRTLY-GIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRKY 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	85/243 (35%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	85/243 (35%)