Protein Alignment Corin and Prss50

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_666339.2
• Gene: Prss50 / 235631
• MGIID: 2447303
• Length: 439
• Species: Mus musculus
• Alignment Length: 304
• Identity: 77/304 - (25%)
• Similarity: 132/304 - (43%)
• Gaps: 39/304 - (12%)

  Fly  1067 QEFANCKKTEDYPMADLTCSNYE---------CGRVKRGRHKPSRRIIGGTQASPGNWPFLAAIL 1122
            |..|..|......|.|.|.|..:         ||    ..|:|. ..:...:|....||::.::.
Mouse   126 QTMAPLKTVGTLGMMDTTGSVLKTVHSSNLPFCG----SSHEPD-PTLRDPEAMTRRWPWMVSVQ 185

  Fly  1123 GGPEKIFYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHP 1187
            .....|  |||:||:.|||||.:||:....|    ::.::.|....|....:...|.|..||.:.
Mouse   186 ANGSHI--CAGILIASQWVLTVAHCLSQNHV----NYIVRAGSPWINQTAGTSSDVPVHRVIINH 244

  Fly  1188 QYNMA-----IAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPK 1247
            .|...     :...:||.|.:|...:.:.:::.|:|||.... .:...:||||.|||........
Mouse   245 GYQPRRYWSWVGRAHDIGLLKLKWGLKYSKYVWPICLPGLDY-VVEDSSLCTVTGWGYPRANGIW 308

  Fly  1248 STYEYIVNEVQVPIITRNQCDEWLDNLT--------VSEGMVCAGFDDGGKDACQGDSGGPLLCP 1304
            ..::.: .|.:|.|:...:||.:....:        ::..|:||. |:..::.|...:|.||:|.
Mouse   309 PQFQSL-QEKEVSILNSKKCDHFYHKFSRISSLVRIINPQMICAS-DNNREEFCYEITGEPLVCS 371

  Fly  1305 YPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQEQIA 1348
            ..|   .|::.|::|||..|.....|.::..|..|.|||.::::
Mouse   372 SDG---TWYLVGMMSWGPGCKKSEAPPIFLQVSYYRPWIWDRLS 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	66/254 (26%)
Prss50	NP_666339.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..130		1/3 (33%)
		Tryp_SPc	177..407	CDD:238113	63/241 (26%)